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Side-by-side financial comparison of Altimmune, Inc. (ALT) and Shuttle Pharmaceuticals Holdings, Inc. (SHPH). Click either name above to swap in a different company.

Altimmune, Inc. is the larger business by last-quarter revenue ($26.0K vs $22.0K, roughly 1.2× Shuttle Pharmaceuticals Holdings, Inc.). On growth, Altimmune, Inc. posted the faster year-over-year revenue change (420.0% vs 14.0%).

Altimmune, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies, vaccines, and peptide-based therapies. Its pipeline covers infectious disease prevention, liver disease treatments, and metabolic disorder therapies, serving global biopharmaceutical and healthcare markets while advancing candidates through clinical trials.

Shuttle Pharmaceuticals Holdings, Inc. is a US-based clinical-stage biopharmaceutical company focused on developing novel radioprotective therapies and cancer supportive care products. It primarily operates in the oncology care segment, targeting unmet medical needs to reduce side effects of radiation therapy for cancer patients, and collaborates with clinical research partners to advance its late-stage product pipeline.

ALT vs SHPH — Head-to-Head

Bigger by revenue
ALT
ALT
1.2× larger
ALT
$26.0K
$22.0K
SHPH
Growing faster (revenue YoY)
ALT
ALT
+406.0% gap
ALT
420.0%
14.0%
SHPH

Income Statement — Q4 FY2025 vs Q2 FY2024

Metric
ALT
ALT
SHPH
SHPH
Revenue
$26.0K
$22.0K
Net Profit
$-2.0M
Gross Margin
Operating Margin
-6751.5%
Net Margin
-9249.6%
Revenue YoY
420.0%
14.0%
Net Profit YoY
-18.0%
7.0%
EPS (diluted)
$-24.12

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALT
ALT
SHPH
SHPH
Q4 25
$26.0K
Q3 25
$5.0K
Q2 25
$5.0K
Q1 25
$5.0K
Q4 24
$5.0K
Q3 24
$5.0K
Q2 24
$5.0K
$22.0K
Q1 24
$5.0K
$13.7K
Net Profit
ALT
ALT
SHPH
SHPH
Q4 25
Q3 25
$-19.0M
Q2 25
$-22.1M
Q1 25
$-19.6M
Q4 24
Q3 24
$-22.8M
Q2 24
$-24.6M
$-2.0M
Q1 24
$-24.4M
$-1.7M
Operating Margin
ALT
ALT
SHPH
SHPH
Q4 25
Q3 25
-417180.0%
Q2 25
-458440.0%
Q1 25
-436300.0%
Q4 24
Q3 24
-495340.0%
Q2 24
-534900.0%
-6751.5%
Q1 24
-535880.0%
-10144.7%
Net Margin
ALT
ALT
SHPH
SHPH
Q4 25
Q3 25
-380280.0%
Q2 25
-442920.0%
Q1 25
-391500.0%
Q4 24
Q3 24
-456900.0%
Q2 24
-492800.0%
-9249.6%
Q1 24
-487880.0%
-12680.6%
EPS (diluted)
ALT
ALT
SHPH
SHPH
Q4 25
Q3 25
$-0.21
Q2 25
$-0.27
Q1 25
$-0.26
Q4 24
Q3 24
$-0.32
Q2 24
$-0.35
$-24.12
Q1 24
$-0.34
$-0.83

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALT
ALT
SHPH
SHPH
Cash + ST InvestmentsLiquidity on hand
$273.5M
$2.3M
Total DebtLower is stronger
$34.3M
Stockholders' EquityBook value
$224.9M
$801.4K
Total Assets
$279.9M
$2.8M
Debt / EquityLower = less leverage
0.15×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALT
ALT
SHPH
SHPH
Q4 25
$273.5M
Q3 25
$210.8M
Q2 25
$183.1M
Q1 25
$149.8M
Q4 24
$131.9M
Q3 24
$139.4M
Q2 24
$164.9M
$2.3M
Q1 24
$182.0M
$4.2M
Total Debt
ALT
ALT
SHPH
SHPH
Q4 25
$34.3M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ALT
ALT
SHPH
SHPH
Q4 25
$224.9M
Q3 25
$185.6M
Q2 25
$161.4M
Q1 25
$142.2M
Q4 24
$123.5M
Q3 24
$133.4M
Q2 24
$152.5M
$801.4K
Q1 24
$172.9M
$2.8M
Total Assets
ALT
ALT
SHPH
SHPH
Q4 25
$279.9M
Q3 25
$218.4M
Q2 25
$190.3M
Q1 25
$157.3M
Q4 24
$139.3M
Q3 24
$147.9M
Q2 24
$173.3M
$2.8M
Q1 24
$188.4M
$4.8M
Debt / Equity
ALT
ALT
SHPH
SHPH
Q4 25
0.15×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALT
ALT
SHPH
SHPH
Operating Cash FlowLast quarter
$-67.5M
$-1.4M
Free Cash FlowOCF − Capex
$-67.5M
FCF MarginFCF / Revenue
-259792.3%
Capex IntensityCapex / Revenue
42.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALT
ALT
SHPH
SHPH
Q4 25
$-67.5M
Q3 25
$-11.9M
Q2 25
$-19.4M
Q1 25
$-16.8M
Q4 24
$-79.8M
Q3 24
$-27.1M
Q2 24
$-18.1M
$-1.4M
Q1 24
$-16.4M
$-1.2M
Free Cash Flow
ALT
ALT
SHPH
SHPH
Q4 25
$-67.5M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
ALT
ALT
SHPH
SHPH
Q4 25
-259792.3%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
ALT
ALT
SHPH
SHPH
Q4 25
42.3%
Q3 25
0.0%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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