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Side-by-side financial comparison of Amphastar Pharmaceuticals, Inc. (AMPH) and Pacira BioSciences, Inc. (PCRX). Click either name above to swap in a different company.

Pacira BioSciences, Inc. is the larger business by last-quarter revenue ($196.9M vs $183.1M, roughly 1.1× Amphastar Pharmaceuticals, Inc.). On growth, Pacira BioSciences, Inc. posted the faster year-over-year revenue change (5.1% vs -1.8%). Pacira BioSciences, Inc. produced more free cash flow last quarter ($43.5M vs $24.6M). Over the past eight quarters, Pacira BioSciences, Inc.'s revenue compounded faster (8.5% CAGR vs 3.2%).

Amphastar Pharmaceuticals is a publicly traded American speciality pharmaceutical company. It was incorporated in May 2004 and primarily develops, manufactures, and sells inhalation and intranasal products.

Pacira BioSciences, Inc. is a specialty pharmaceutical company focused on developing and commercializing non-opioid pain management solutions. Its core product line targets post-surgical pain relief for patients, serving hospitals, ambulatory surgery centers and other healthcare providers primarily in the U.S., with ongoing expansion efforts in select international markets.

AMPH vs PCRX — Head-to-Head

Bigger by revenue
PCRX
PCRX
1.1× larger
PCRX
$196.9M
$183.1M
AMPH
Growing faster (revenue YoY)
PCRX
PCRX
+7.0% gap
PCRX
5.1%
-1.8%
AMPH
More free cash flow
PCRX
PCRX
$18.9M more FCF
PCRX
$43.5M
$24.6M
AMPH
Faster 2-yr revenue CAGR
PCRX
PCRX
Annualised
PCRX
8.5%
3.2%
AMPH

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AMPH
AMPH
PCRX
PCRX
Revenue
$183.1M
$196.9M
Net Profit
$24.4M
Gross Margin
46.8%
79.5%
Operating Margin
19.4%
1.2%
Net Margin
13.3%
Revenue YoY
-1.8%
5.1%
Net Profit YoY
-35.7%
EPS (diluted)
$0.51
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMPH
AMPH
PCRX
PCRX
Q4 25
$183.1M
$196.9M
Q3 25
$191.8M
$179.5M
Q2 25
$174.4M
$181.1M
Q1 25
$170.5M
$168.9M
Q4 24
$186.5M
$187.3M
Q3 24
$191.2M
$168.6M
Q2 24
$182.4M
$178.0M
Q1 24
$171.8M
$167.1M
Net Profit
AMPH
AMPH
PCRX
PCRX
Q4 25
$24.4M
Q3 25
$17.4M
$5.4M
Q2 25
$31.0M
$-4.8M
Q1 25
$25.3M
$4.8M
Q4 24
$38.0M
Q3 24
$40.4M
$-143.5M
Q2 24
$37.9M
$18.9M
Q1 24
$43.2M
$9.0M
Gross Margin
AMPH
AMPH
PCRX
PCRX
Q4 25
46.8%
79.5%
Q3 25
51.4%
80.9%
Q2 25
49.6%
77.4%
Q1 25
50.0%
79.7%
Q4 24
46.5%
78.7%
Q3 24
53.3%
76.9%
Q2 24
52.2%
75.1%
Q1 24
52.4%
71.6%
Operating Margin
AMPH
AMPH
PCRX
PCRX
Q4 25
19.4%
1.2%
Q3 25
13.2%
3.5%
Q2 25
24.2%
4.7%
Q1 25
21.9%
1.2%
Q4 24
24.2%
13.2%
Q3 24
29.8%
-82.8%
Q2 24
30.3%
15.9%
Q1 24
27.9%
7.9%
Net Margin
AMPH
AMPH
PCRX
PCRX
Q4 25
13.3%
Q3 25
9.0%
3.0%
Q2 25
17.8%
-2.7%
Q1 25
14.8%
2.8%
Q4 24
20.4%
Q3 24
21.1%
-85.1%
Q2 24
20.8%
10.6%
Q1 24
25.1%
5.4%
EPS (diluted)
AMPH
AMPH
PCRX
PCRX
Q4 25
$0.51
$0.05
Q3 25
$0.37
$0.12
Q2 25
$0.64
$-0.11
Q1 25
$0.51
$0.10
Q4 24
$0.74
$0.38
Q3 24
$0.78
$-3.11
Q2 24
$0.73
$0.39
Q1 24
$0.81
$0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMPH
AMPH
PCRX
PCRX
Cash + ST InvestmentsLiquidity on hand
$282.8M
$238.4M
Total DebtLower is stronger
$608.7M
$372.2M
Stockholders' EquityBook value
$788.8M
$693.1M
Total Assets
$1.6B
$1.3B
Debt / EquityLower = less leverage
0.77×
0.54×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMPH
AMPH
PCRX
PCRX
Q4 25
$282.8M
$238.4M
Q3 25
$276.2M
$246.3M
Q2 25
$231.8M
$445.9M
Q1 25
$236.9M
$493.6M
Q4 24
$221.6M
$484.6M
Q3 24
$250.5M
$453.8M
Q2 24
$217.8M
$404.2M
Q1 24
$289.6M
$325.9M
Total Debt
AMPH
AMPH
PCRX
PCRX
Q4 25
$608.7M
$372.2M
Q3 25
$608.6M
$376.7M
Q2 25
$607.7M
$580.5M
Q1 25
$603.9M
$583.4M
Q4 24
$601.6M
$585.3M
Q3 24
$596.4M
Q2 24
$586.9M
Q1 24
$594.0M
Stockholders' Equity
AMPH
AMPH
PCRX
PCRX
Q4 25
$788.8M
$693.1M
Q3 25
$776.7M
$727.2M
Q2 25
$757.5M
$757.8M
Q1 25
$751.3M
$798.5M
Q4 24
$732.3M
$778.3M
Q3 24
$727.7M
$749.6M
Q2 24
$713.3M
$879.3M
Q1 24
$672.4M
$892.2M
Total Assets
AMPH
AMPH
PCRX
PCRX
Q4 25
$1.6B
$1.3B
Q3 25
$1.7B
$1.3B
Q2 25
$1.6B
$1.5B
Q1 25
$1.6B
$1.6B
Q4 24
$1.6B
$1.6B
Q3 24
$1.5B
$1.5B
Q2 24
$1.5B
$1.6B
Q1 24
$1.6B
$1.6B
Debt / Equity
AMPH
AMPH
PCRX
PCRX
Q4 25
0.77×
0.54×
Q3 25
0.78×
0.52×
Q2 25
0.80×
0.77×
Q1 25
0.80×
0.73×
Q4 24
0.82×
0.75×
Q3 24
0.82×
Q2 24
0.82×
Q1 24
0.88×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMPH
AMPH
PCRX
PCRX
Operating Cash FlowLast quarter
$32.9M
$43.7M
Free Cash FlowOCF − Capex
$24.6M
$43.5M
FCF MarginFCF / Revenue
13.4%
22.1%
Capex IntensityCapex / Revenue
4.5%
0.1%
Cash ConversionOCF / Net Profit
1.35×
TTM Free Cash FlowTrailing 4 quarters
$121.2M
$136.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMPH
AMPH
PCRX
PCRX
Q4 25
$32.9M
$43.7M
Q3 25
$52.6M
$60.8M
Q2 25
$35.6M
$12.0M
Q1 25
$35.1M
$35.5M
Q4 24
$29.0M
$33.1M
Q3 24
$60.0M
$53.9M
Q2 24
$69.1M
$53.2M
Q1 24
$55.3M
$49.1M
Free Cash Flow
AMPH
AMPH
PCRX
PCRX
Q4 25
$24.6M
$43.5M
Q3 25
$47.2M
$57.0M
Q2 25
$25.0M
$9.3M
Q1 25
$24.4M
$26.9M
Q4 24
$16.6M
$31.0M
Q3 24
$46.2M
$49.8M
Q2 24
$63.1M
$51.6M
Q1 24
$46.5M
$46.3M
FCF Margin
AMPH
AMPH
PCRX
PCRX
Q4 25
13.4%
22.1%
Q3 25
24.6%
31.7%
Q2 25
14.3%
5.1%
Q1 25
14.3%
15.9%
Q4 24
8.9%
16.6%
Q3 24
24.1%
29.6%
Q2 24
34.6%
29.0%
Q1 24
27.1%
27.7%
Capex Intensity
AMPH
AMPH
PCRX
PCRX
Q4 25
4.5%
0.1%
Q3 25
2.8%
2.2%
Q2 25
6.1%
1.5%
Q1 25
6.3%
5.1%
Q4 24
6.7%
1.1%
Q3 24
7.2%
2.4%
Q2 24
3.3%
0.9%
Q1 24
5.1%
1.7%
Cash Conversion
AMPH
AMPH
PCRX
PCRX
Q4 25
1.35×
Q3 25
3.03×
11.20×
Q2 25
1.15×
Q1 25
1.39×
7.37×
Q4 24
0.76×
Q3 24
1.48×
Q2 24
1.82×
2.82×
Q1 24
1.28×
5.47×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMPH
AMPH

Other Products$62.4M34%
Baqsimi$46.7M26%
Primatenemist$27.9M15%
Epinephrine$17.1M9%
Lidocaine$14.9M8%
Glucagon$14.1M8%

PCRX
PCRX

EXPAREL$155.8M79%
ZILRETTA$33.0M17%
Iovera$7.0M4%

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