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Side-by-side financial comparison of Amphastar Pharmaceuticals, Inc. (AMPH) and TG THERAPEUTICS, INC. (TGTX). Click either name above to swap in a different company.

TG THERAPEUTICS, INC. is the larger business by last-quarter revenue ($192.6M vs $183.1M, roughly 1.1× Amphastar Pharmaceuticals, Inc.). Amphastar Pharmaceuticals, Inc. runs the higher net margin — 13.3% vs 12.0%, a 1.4% gap on every dollar of revenue. On growth, TG THERAPEUTICS, INC. posted the faster year-over-year revenue change (78.0% vs -1.8%). Amphastar Pharmaceuticals, Inc. produced more free cash flow last quarter ($24.6M vs $19.6M). Over the past eight quarters, TG THERAPEUTICS, INC.'s revenue compounded faster (74.2% CAGR vs 3.2%).

Amphastar Pharmaceuticals is a publicly traded American speciality pharmaceutical company. It was incorporated in May 2004 and primarily develops, manufactures, and sells inhalation and intranasal products.

TG Therapeutics is a commercial-stage biopharmaceutical company focused on developing and commercializing innovative therapies for patients with B-cell malignancies, autoimmune diseases and neurodegenerative disorders. Its core operating markets are North America and Europe, with key product segments including targeted monoclonal antibodies and oral small molecule treatments.

AMPH vs TGTX — Head-to-Head

Bigger by revenue
TGTX
TGTX
1.1× larger
TGTX
$192.6M
$183.1M
AMPH
Growing faster (revenue YoY)
TGTX
TGTX
+79.8% gap
TGTX
78.0%
-1.8%
AMPH
Higher net margin
AMPH
AMPH
1.4% more per $
AMPH
13.3%
12.0%
TGTX
More free cash flow
AMPH
AMPH
$5.0M more FCF
AMPH
$24.6M
$19.6M
TGTX
Faster 2-yr revenue CAGR
TGTX
TGTX
Annualised
TGTX
74.2%
3.2%
AMPH

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AMPH
AMPH
TGTX
TGTX
Revenue
$183.1M
$192.6M
Net Profit
$24.4M
$23.0M
Gross Margin
46.8%
80.2%
Operating Margin
19.4%
26.2%
Net Margin
13.3%
12.0%
Revenue YoY
-1.8%
78.0%
Net Profit YoY
-35.7%
-1.3%
EPS (diluted)
$0.51
$0.14

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMPH
AMPH
TGTX
TGTX
Q4 25
$183.1M
$192.6M
Q3 25
$191.8M
$161.7M
Q2 25
$174.4M
$141.1M
Q1 25
$170.5M
$120.9M
Q4 24
$186.5M
$108.2M
Q3 24
$191.2M
$83.9M
Q2 24
$182.4M
$73.5M
Q1 24
$171.8M
$63.5M
Net Profit
AMPH
AMPH
TGTX
TGTX
Q4 25
$24.4M
$23.0M
Q3 25
$17.4M
$390.9M
Q2 25
$31.0M
$28.2M
Q1 25
$25.3M
$5.1M
Q4 24
$38.0M
$23.3M
Q3 24
$40.4M
$3.9M
Q2 24
$37.9M
$6.9M
Q1 24
$43.2M
$-10.7M
Gross Margin
AMPH
AMPH
TGTX
TGTX
Q4 25
46.8%
80.2%
Q3 25
51.4%
82.6%
Q2 25
49.6%
86.6%
Q1 25
50.0%
87.1%
Q4 24
46.5%
85.8%
Q3 24
53.3%
88.9%
Q2 24
52.2%
88.7%
Q1 24
52.4%
91.4%
Operating Margin
AMPH
AMPH
TGTX
TGTX
Q4 25
19.4%
26.2%
Q3 25
13.2%
18.2%
Q2 25
24.2%
24.7%
Q1 25
21.9%
7.1%
Q4 24
24.2%
27.7%
Q3 24
29.8%
14.8%
Q2 24
30.3%
12.0%
Q1 24
27.9%
-14.6%
Net Margin
AMPH
AMPH
TGTX
TGTX
Q4 25
13.3%
12.0%
Q3 25
9.0%
241.7%
Q2 25
17.8%
20.0%
Q1 25
14.8%
4.2%
Q4 24
20.4%
21.6%
Q3 24
21.1%
4.6%
Q2 24
20.8%
9.4%
Q1 24
25.1%
-16.9%
EPS (diluted)
AMPH
AMPH
TGTX
TGTX
Q4 25
$0.51
$0.14
Q3 25
$0.37
$2.43
Q2 25
$0.64
$0.17
Q1 25
$0.51
$0.03
Q4 24
$0.74
$0.16
Q3 24
$0.78
$0.02
Q2 24
$0.73
$0.04
Q1 24
$0.81
$-0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMPH
AMPH
TGTX
TGTX
Cash + ST InvestmentsLiquidity on hand
$282.8M
$142.0M
Total DebtLower is stronger
$608.7M
Stockholders' EquityBook value
$788.8M
$648.0M
Total Assets
$1.6B
$1.1B
Debt / EquityLower = less leverage
0.77×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMPH
AMPH
TGTX
TGTX
Q4 25
$282.8M
$142.0M
Q3 25
$276.2M
$131.6M
Q2 25
$231.8M
$251.9M
Q1 25
$236.9M
$276.2M
Q4 24
$221.6M
$311.0M
Q3 24
$250.5M
$341.0M
Q2 24
$217.8M
$217.3M
Q1 24
$289.6M
$209.8M
Total Debt
AMPH
AMPH
TGTX
TGTX
Q4 25
$608.7M
Q3 25
$608.6M
Q2 25
$607.7M
Q1 25
$603.9M
Q4 24
$601.6M
Q3 24
$596.4M
Q2 24
$586.9M
Q1 24
$594.0M
Stockholders' Equity
AMPH
AMPH
TGTX
TGTX
Q4 25
$788.8M
$648.0M
Q3 25
$776.7M
$607.2M
Q2 25
$757.5M
$276.4M
Q1 25
$751.3M
$237.3M
Q4 24
$732.3M
$222.4M
Q3 24
$727.7M
$192.2M
Q2 24
$713.3M
$177.6M
Q1 24
$672.4M
$160.1M
Total Assets
AMPH
AMPH
TGTX
TGTX
Q4 25
$1.6B
$1.1B
Q3 25
$1.7B
$1.0B
Q2 25
$1.6B
$702.6M
Q1 25
$1.6B
$656.7M
Q4 24
$1.6B
$577.7M
Q3 24
$1.5B
$586.0M
Q2 24
$1.5B
$401.2M
Q1 24
$1.6B
$373.3M
Debt / Equity
AMPH
AMPH
TGTX
TGTX
Q4 25
0.77×
Q3 25
0.78×
Q2 25
0.80×
Q1 25
0.80×
Q4 24
0.82×
Q3 24
0.82×
Q2 24
0.82×
Q1 24
0.88×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMPH
AMPH
TGTX
TGTX
Operating Cash FlowLast quarter
$32.9M
$19.7M
Free Cash FlowOCF − Capex
$24.6M
$19.6M
FCF MarginFCF / Revenue
13.4%
10.2%
Capex IntensityCapex / Revenue
4.5%
0.0%
Cash ConversionOCF / Net Profit
1.35×
0.85×
TTM Free Cash FlowTrailing 4 quarters
$121.2M
$-25.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMPH
AMPH
TGTX
TGTX
Q4 25
$32.9M
$19.7M
Q3 25
$52.6M
$-23.2M
Q2 25
$35.6M
$7.4M
Q1 25
$35.1M
$-28.7M
Q4 24
$29.0M
$-25.6M
Q3 24
$60.0M
$-12.2M
Q2 24
$69.1M
$5.5M
Q1 24
$55.3M
$-8.2M
Free Cash Flow
AMPH
AMPH
TGTX
TGTX
Q4 25
$24.6M
$19.6M
Q3 25
$47.2M
$-23.2M
Q2 25
$25.0M
$7.4M
Q1 25
$24.4M
$-28.7M
Q4 24
$16.6M
$-25.7M
Q3 24
$46.2M
$-12.2M
Q2 24
$63.1M
Q1 24
$46.5M
FCF Margin
AMPH
AMPH
TGTX
TGTX
Q4 25
13.4%
10.2%
Q3 25
24.6%
-14.4%
Q2 25
14.3%
5.2%
Q1 25
14.3%
-23.8%
Q4 24
8.9%
-23.7%
Q3 24
24.1%
-14.6%
Q2 24
34.6%
Q1 24
27.1%
Capex Intensity
AMPH
AMPH
TGTX
TGTX
Q4 25
4.5%
0.0%
Q3 25
2.8%
0.0%
Q2 25
6.1%
0.0%
Q1 25
6.3%
0.0%
Q4 24
6.7%
0.0%
Q3 24
7.2%
0.0%
Q2 24
3.3%
0.0%
Q1 24
5.1%
0.0%
Cash Conversion
AMPH
AMPH
TGTX
TGTX
Q4 25
1.35×
0.85×
Q3 25
3.03×
-0.06×
Q2 25
1.15×
0.26×
Q1 25
1.39×
-5.67×
Q4 24
0.76×
-1.10×
Q3 24
1.48×
-3.15×
Q2 24
1.82×
0.80×
Q1 24
1.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMPH
AMPH

Other Products$62.4M34%
Baqsimi$46.7M26%
Primatenemist$27.9M15%
Epinephrine$17.1M9%
Lidocaine$14.9M8%
Glucagon$14.1M8%

TGTX
TGTX

Products$189.1M98%
License$3.5M2%

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