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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Cohen & Co Inc. (COHN). Click either name above to swap in a different company.

Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $102.7M, roughly 1.9× Cohen & Co Inc.). On growth, Cohen & Co Inc. posted the faster year-over-year revenue change (454.1% vs -5.9%). Cohen & Co Inc. produced more free cash flow last quarter ($-2.5M vs $-14.3M). Over the past eight quarters, Cohen & Co Inc.'s revenue compounded faster (135.3% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

George Cohen, Sons and Company was a scrap metal merchant with offices in Commercial Road, London. The company was founded by George Henry Cohen (d.1890) as Messrs. George Cohen & Co. in 1834 and changed its name to George Cohen, Sons and Co. in 1883 on the appointment of Michael Cohen, son of the founder. After the First World War the company won a number of large contracts to dispose of surplus munitions including "400,000 tons of high explosives and other shells". The company also engaged ...

APLS vs COHN — Head-to-Head

Bigger by revenue
APLS
APLS
1.9× larger
APLS
$199.9M
$102.7M
COHN
Growing faster (revenue YoY)
COHN
COHN
+460.1% gap
COHN
454.1%
-5.9%
APLS
More free cash flow
COHN
COHN
$11.8M more FCF
COHN
$-2.5M
$-14.3M
APLS
Faster 2-yr revenue CAGR
COHN
COHN
Annualised
COHN
135.3%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
COHN
COHN
Revenue
$199.9M
$102.7M
Net Profit
$-59.0M
Gross Margin
Operating Margin
-25.6%
29.2%
Net Margin
-29.5%
Revenue YoY
-5.9%
454.1%
Net Profit YoY
-62.2%
EPS (diluted)
$-0.40
$0.77

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
COHN
COHN
Q4 25
$199.9M
$102.7M
Q3 25
$458.6M
$84.2M
Q2 25
$178.5M
$59.9M
Q1 25
$166.8M
$28.7M
Q4 24
$212.5M
$18.5M
Q3 24
$196.8M
$31.7M
Q2 24
$199.7M
$10.8M
Q1 24
$172.3M
$18.6M
Net Profit
APLS
APLS
COHN
COHN
Q4 25
$-59.0M
Q3 25
$215.7M
$4.6M
Q2 25
$-42.2M
$1.4M
Q1 25
$-92.2M
$329.0K
Q4 24
$-36.4M
Q3 24
$-57.4M
$2.1M
Q2 24
$-37.7M
$-2.3M
Q1 24
$-66.4M
$2.0M
Operating Margin
APLS
APLS
COHN
COHN
Q4 25
-25.6%
29.2%
Q3 25
48.7%
25.8%
Q2 25
-18.6%
12.5%
Q1 25
-50.0%
0.4%
Q4 24
-12.3%
-29.7%
Q3 24
-24.0%
22.8%
Q2 24
-14.7%
-59.0%
Q1 24
-36.0%
-18.2%
Net Margin
APLS
APLS
COHN
COHN
Q4 25
-29.5%
Q3 25
47.0%
5.5%
Q2 25
-23.6%
2.4%
Q1 25
-55.3%
1.1%
Q4 24
-17.1%
Q3 24
-29.2%
6.8%
Q2 24
-18.9%
-21.8%
Q1 24
-38.5%
10.9%
EPS (diluted)
APLS
APLS
COHN
COHN
Q4 25
$-0.40
$0.77
Q3 25
$1.67
$2.58
Q2 25
$-0.33
$0.81
Q1 25
$-0.74
$0.19
Q4 24
$-0.30
$-1.20
Q3 24
$-0.46
$1.31
Q2 24
$-0.30
$-1.47
Q1 24
$-0.54
$1.28

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
COHN
COHN
Cash + ST InvestmentsLiquidity on hand
$466.2M
$56.8M
Total DebtLower is stronger
$32.9M
Stockholders' EquityBook value
$370.1M
$51.1M
Total Assets
$1.1B
$700.6M
Debt / EquityLower = less leverage
0.64×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
COHN
COHN
Q4 25
$466.2M
$56.8M
Q3 25
$479.2M
$54.7M
Q2 25
$370.0M
$26.0M
Q1 25
$358.4M
$14.0M
Q4 24
$411.3M
$19.6M
Q3 24
$396.9M
$14.3M
Q2 24
$360.1M
$9.6M
Q1 24
$325.9M
$11.8M
Total Debt
APLS
APLS
COHN
COHN
Q4 25
$32.9M
Q3 25
$32.7M
Q2 25
$32.6M
Q1 25
$35.0M
Q4 24
$34.9M
Q3 24
$34.9M
Q2 24
$29.7M
Q1 24
$93.1M
$29.7M
Stockholders' Equity
APLS
APLS
COHN
COHN
Q4 25
$370.1M
$51.1M
Q3 25
$401.2M
$47.8M
Q2 25
$156.3M
$43.4M
Q1 25
$164.2M
$42.0M
Q4 24
$228.5M
$41.7M
Q3 24
$237.1M
$43.8M
Q2 24
$264.3M
$41.7M
Q1 24
$266.7M
$43.8M
Total Assets
APLS
APLS
COHN
COHN
Q4 25
$1.1B
$700.6M
Q3 25
$1.1B
$773.9M
Q2 25
$821.4M
$1.1B
Q1 25
$807.3M
$978.0M
Q4 24
$885.1M
$971.1M
Q3 24
$901.9M
$818.0M
Q2 24
$904.5M
$826.0M
Q1 24
$831.9M
$1.1B
Debt / Equity
APLS
APLS
COHN
COHN
Q4 25
0.64×
Q3 25
0.68×
Q2 25
0.75×
Q1 25
0.83×
Q4 24
0.84×
Q3 24
0.80×
Q2 24
0.71×
Q1 24
0.35×
0.68×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
COHN
COHN
Operating Cash FlowLast quarter
$-14.2M
$-2.1M
Free Cash FlowOCF − Capex
$-14.3M
$-2.5M
FCF MarginFCF / Revenue
-7.1%
-2.4%
Capex IntensityCapex / Revenue
0.1%
0.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$26.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
COHN
COHN
Q4 25
$-14.2M
$-2.1M
Q3 25
$108.5M
$22.4M
Q2 25
$4.4M
$13.3M
Q1 25
$-53.4M
$-6.4M
Q4 24
$19.4M
$4.4M
Q3 24
$34.1M
$4.1M
Q2 24
$-8.3M
$-4.2M
Q1 24
$-133.0M
$5.1M
Free Cash Flow
APLS
APLS
COHN
COHN
Q4 25
$-14.3M
$-2.5M
Q3 25
$108.3M
$22.2M
Q2 25
$4.4M
$12.9M
Q1 25
$-53.4M
$-6.5M
Q4 24
$19.3M
$4.0M
Q3 24
$3.8M
Q2 24
$-8.4M
$-4.6M
Q1 24
$-133.3M
$5.0M
FCF Margin
APLS
APLS
COHN
COHN
Q4 25
-7.1%
-2.4%
Q3 25
23.6%
26.3%
Q2 25
2.5%
21.6%
Q1 25
-32.0%
-22.7%
Q4 24
9.1%
21.4%
Q3 24
12.0%
Q2 24
-4.2%
-42.4%
Q1 24
-77.3%
27.1%
Capex Intensity
APLS
APLS
COHN
COHN
Q4 25
0.1%
0.4%
Q3 25
0.0%
0.3%
Q2 25
0.0%
0.7%
Q1 25
0.0%
0.5%
Q4 24
0.0%
2.5%
Q3 24
0.0%
1.0%
Q2 24
0.0%
3.5%
Q1 24
0.2%
0.5%
Cash Conversion
APLS
APLS
COHN
COHN
Q4 25
Q3 25
0.50×
4.88×
Q2 25
9.48×
Q1 25
-19.37×
Q4 24
Q3 24
1.91×
Q2 24
Q1 24
2.54×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

COHN
COHN

Capital Markets$68.5M67%
Other$25.7M25%
Gestational Repo Business$5.6M5%
Asset Management Segment$2.9M3%

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