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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Northwest Bancshares, Inc. (NWBI). Click either name above to swap in a different company.
Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $175.1M, roughly 1.1× Northwest Bancshares, Inc.). Northwest Bancshares, Inc. runs the higher net margin — 28.9% vs -29.5%, a 58.4% gap on every dollar of revenue. Over the past eight quarters, Northwest Bancshares, Inc.'s revenue compounded faster (33.7% CAGR vs 7.7%).
Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.
Northwest Bank is a bank headquartered in Warren, Pennsylvania. It is the leading subsidiary of Northwest Bancshares, Inc., a bank holding company, and operates 151 branches in Pennsylvania, Western New York, Northeast Ohio, Appalachian Ohio, and Indiana.
APLS vs NWBI — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $199.9M | $175.1M |
| Net Profit | $-59.0M | $50.5M |
| Gross Margin | — | — |
| Operating Margin | -25.6% | — |
| Net Margin | -29.5% | 28.9% |
| Revenue YoY | -5.9% | — |
| Net Profit YoY | -62.2% | — |
| EPS (diluted) | $-0.40 | $0.34 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $175.1M | ||
| Q4 25 | $199.9M | $179.9M | ||
| Q3 25 | $458.6M | $168.2M | ||
| Q2 25 | $178.5M | $150.4M | ||
| Q1 25 | $166.8M | $156.2M | ||
| Q4 24 | $212.5M | $154.3M | ||
| Q3 24 | $196.8M | $139.1M | ||
| Q2 24 | $199.7M | $98.0M |
| Q1 26 | — | $50.5M | ||
| Q4 25 | $-59.0M | — | ||
| Q3 25 | $215.7M | $3.2M | ||
| Q2 25 | $-42.2M | $33.7M | ||
| Q1 25 | $-92.2M | $43.5M | ||
| Q4 24 | $-36.4M | — | ||
| Q3 24 | $-57.4M | $33.6M | ||
| Q2 24 | $-37.7M | $4.7M |
| Q1 26 | — | — | ||
| Q4 25 | -25.6% | 32.6% | ||
| Q3 25 | 48.7% | 2.1% | ||
| Q2 25 | -18.6% | 29.3% | ||
| Q1 25 | -50.0% | 36.2% | ||
| Q4 24 | -12.3% | 27.5% | ||
| Q3 24 | -24.0% | 31.3% | ||
| Q2 24 | -14.7% | 6.1% |
| Q1 26 | — | 28.9% | ||
| Q4 25 | -29.5% | — | ||
| Q3 25 | 47.0% | 1.9% | ||
| Q2 25 | -23.6% | 22.4% | ||
| Q1 25 | -55.3% | 27.8% | ||
| Q4 24 | -17.1% | — | ||
| Q3 24 | -29.2% | 24.2% | ||
| Q2 24 | -18.9% | 4.8% |
| Q1 26 | — | $0.34 | ||
| Q4 25 | $-0.40 | $0.30 | ||
| Q3 25 | $1.67 | $0.02 | ||
| Q2 25 | $-0.33 | $0.26 | ||
| Q1 25 | $-0.74 | $0.34 | ||
| Q4 24 | $-0.30 | $0.26 | ||
| Q3 24 | $-0.46 | $0.26 | ||
| Q2 24 | $-0.30 | $0.04 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $466.2M | $286.7M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $370.1M | $1.9B |
| Total Assets | $1.1B | $16.9B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $286.7M | ||
| Q4 25 | $466.2M | — | ||
| Q3 25 | $479.2M | — | ||
| Q2 25 | $370.0M | — | ||
| Q1 25 | $358.4M | — | ||
| Q4 24 | $411.3M | — | ||
| Q3 24 | $396.9M | — | ||
| Q2 24 | $360.1M | — |
| Q1 26 | — | $1.9B | ||
| Q4 25 | $370.1M | $1.9B | ||
| Q3 25 | $401.2M | $1.9B | ||
| Q2 25 | $156.3M | $1.6B | ||
| Q1 25 | $164.2M | $1.6B | ||
| Q4 24 | $228.5M | $1.6B | ||
| Q3 24 | $237.1M | $1.6B | ||
| Q2 24 | $264.3M | $1.6B |
| Q1 26 | — | $16.9B | ||
| Q4 25 | $1.1B | $16.8B | ||
| Q3 25 | $1.1B | $16.4B | ||
| Q2 25 | $821.4M | $14.5B | ||
| Q1 25 | $807.3M | $14.5B | ||
| Q4 24 | $885.1M | $14.4B | ||
| Q3 24 | $901.9M | $14.4B | ||
| Q2 24 | $904.5M | $14.4B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-14.2M | — |
| Free Cash FlowOCF − Capex | $-14.3M | — |
| FCF MarginFCF / Revenue | -7.1% | — |
| Capex IntensityCapex / Revenue | 0.1% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $45.0M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $-14.2M | $153.4M | ||
| Q3 25 | $108.5M | $41.9M | ||
| Q2 25 | $4.4M | $-2.3M | ||
| Q1 25 | $-53.4M | $107.6M | ||
| Q4 24 | $19.4M | $127.7M | ||
| Q3 24 | $34.1M | $93.3M | ||
| Q2 24 | $-8.3M | $40.7M |
| Q1 26 | — | — | ||
| Q4 25 | $-14.3M | $141.8M | ||
| Q3 25 | $108.3M | $38.3M | ||
| Q2 25 | $4.4M | $-6.0M | ||
| Q1 25 | $-53.4M | $105.8M | ||
| Q4 24 | $19.3M | $125.4M | ||
| Q3 24 | — | $93.2M | ||
| Q2 24 | $-8.4M | $37.2M |
| Q1 26 | — | — | ||
| Q4 25 | -7.1% | 78.8% | ||
| Q3 25 | 23.6% | 22.8% | ||
| Q2 25 | 2.5% | -4.0% | ||
| Q1 25 | -32.0% | 67.7% | ||
| Q4 24 | 9.1% | 81.3% | ||
| Q3 24 | — | 67.0% | ||
| Q2 24 | -4.2% | 37.9% |
| Q1 26 | — | — | ||
| Q4 25 | 0.1% | 6.5% | ||
| Q3 25 | 0.0% | 2.2% | ||
| Q2 25 | 0.0% | 2.4% | ||
| Q1 25 | 0.0% | 1.2% | ||
| Q4 24 | 0.0% | 1.5% | ||
| Q3 24 | 0.0% | 0.1% | ||
| Q2 24 | 0.0% | 3.6% |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | 0.50× | 13.24× | ||
| Q2 25 | — | -0.07× | ||
| Q1 25 | — | 2.48× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 2.77× | ||
| Q2 24 | — | 8.56× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
APLS
| Syfovre | $155.2M | 78% |
| Empaveli Pegcetacoplan | $35.1M | 18% |
| Licensing And Other Revenue | $9.6M | 5% |
NWBI
| Net Interest Income | $142.5M | 81% |
| Noninterest Income | $32.6M | 19% |
