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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Northwest Natural Holding Co (NWN). Click either name above to swap in a different company.

Northwest Natural Holding Co is the larger business by last-quarter revenue ($394.2M vs $199.9M, roughly 2.0× Apellis Pharmaceuticals, Inc.). On growth, Northwest Natural Holding Co posted the faster year-over-year revenue change (6.3% vs -5.9%). Apellis Pharmaceuticals, Inc. produced more free cash flow last quarter ($-14.3M vs $-131.0M). Over the past eight quarters, Apellis Pharmaceuticals, Inc.'s revenue compounded faster (7.7% CAGR vs -4.6%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

NW Natural, formerly Northwest Natural Gas Company, is an American publicly traded utility headquartered in Portland, Oregon, United States. Primarily a natural gas distributor, the company services residential, commercial, and industrial customers in Western Oregon and Southwest Washington in the Pacific Northwest. NW Natural also owns water utilities. Founded in 1859, the company has approximately 800,000 customers and revenues of over $1 billion annually.

APLS vs NWN — Head-to-Head

Bigger by revenue
NWN
NWN
2.0× larger
NWN
$394.2M
$199.9M
APLS
Growing faster (revenue YoY)
NWN
NWN
+12.2% gap
NWN
6.3%
-5.9%
APLS
More free cash flow
APLS
APLS
$116.7M more FCF
APLS
$-14.3M
$-131.0M
NWN
Faster 2-yr revenue CAGR
APLS
APLS
Annualised
APLS
7.7%
-4.6%
NWN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
NWN
NWN
Revenue
$199.9M
$394.2M
Net Profit
$-59.0M
Gross Margin
Operating Margin
-25.6%
28.4%
Net Margin
-29.5%
Revenue YoY
-5.9%
6.3%
Net Profit YoY
-62.2%
EPS (diluted)
$-0.40
$1.38

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
NWN
NWN
Q4 25
$199.9M
$394.2M
Q3 25
$458.6M
$164.7M
Q2 25
$178.5M
$236.2M
Q1 25
$166.8M
$494.3M
Q4 24
$212.5M
$370.9M
Q3 24
$196.8M
$136.9M
Q2 24
$199.7M
$211.7M
Q1 24
$172.3M
$433.5M
Net Profit
APLS
APLS
NWN
NWN
Q4 25
$-59.0M
Q3 25
$215.7M
$-29.9M
Q2 25
$-42.2M
$-2.5M
Q1 25
$-92.2M
$87.9M
Q4 24
$-36.4M
Q3 24
$-57.4M
$-27.2M
Q2 24
$-37.7M
$-2.8M
Q1 24
$-66.4M
$63.8M
Operating Margin
APLS
APLS
NWN
NWN
Q4 25
-25.6%
28.4%
Q3 25
48.7%
-7.5%
Q2 25
-18.6%
11.5%
Q1 25
-50.0%
31.2%
Q4 24
-12.3%
22.9%
Q3 24
-24.0%
-14.1%
Q2 24
-14.7%
7.4%
Q1 24
-36.0%
25.3%
Net Margin
APLS
APLS
NWN
NWN
Q4 25
-29.5%
Q3 25
47.0%
-18.1%
Q2 25
-23.6%
-1.1%
Q1 25
-55.3%
17.8%
Q4 24
-17.1%
Q3 24
-29.2%
-19.8%
Q2 24
-18.9%
-1.3%
Q1 24
-38.5%
14.7%
EPS (diluted)
APLS
APLS
NWN
NWN
Q4 25
$-0.40
$1.38
Q3 25
$1.67
$-0.73
Q2 25
$-0.33
$-0.06
Q1 25
$-0.74
$2.18
Q4 24
$-0.30
$1.12
Q3 24
$-0.46
$-0.71
Q2 24
$-0.30
$-0.07
Q1 24
$-0.54
$1.69

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
NWN
NWN
Cash + ST InvestmentsLiquidity on hand
$466.2M
$36.7M
Total DebtLower is stronger
$2.4B
Stockholders' EquityBook value
$370.1M
$1.5B
Total Assets
$1.1B
$6.2B
Debt / EquityLower = less leverage
1.65×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
NWN
NWN
Q4 25
$466.2M
$36.7M
Q3 25
$479.2M
$32.2M
Q2 25
$370.0M
$102.6M
Q1 25
$358.4M
$100.0M
Q4 24
$411.3M
$38.5M
Q3 24
$396.9M
$35.0M
Q2 24
$360.1M
$65.2M
Q1 24
$325.9M
$72.4M
Total Debt
APLS
APLS
NWN
NWN
Q4 25
$2.4B
Q3 25
$2.2B
Q2 25
$2.2B
Q1 25
$2.2B
Q4 24
$1.7B
Q3 24
$1.6B
Q2 24
$1.6B
Q1 24
$93.1M
$1.6B
Stockholders' Equity
APLS
APLS
NWN
NWN
Q4 25
$370.1M
$1.5B
Q3 25
$401.2M
$1.4B
Q2 25
$156.3M
$1.5B
Q1 25
$164.2M
$1.5B
Q4 24
$228.5M
$1.4B
Q3 24
$237.1M
$1.4B
Q2 24
$264.3M
$1.3B
Q1 24
$266.7M
$1.3B
Total Assets
APLS
APLS
NWN
NWN
Q4 25
$1.1B
$6.2B
Q3 25
$1.1B
$5.9B
Q2 25
$821.4M
$5.8B
Q1 25
$807.3M
$5.7B
Q4 24
$885.1M
$5.2B
Q3 24
$901.9M
$4.9B
Q2 24
$904.5M
$4.8B
Q1 24
$831.9M
$4.8B
Debt / Equity
APLS
APLS
NWN
NWN
Q4 25
1.65×
Q3 25
1.56×
Q2 25
1.53×
Q1 25
1.53×
Q4 24
1.23×
Q3 24
1.16×
Q2 24
1.17×
Q1 24
0.35×
1.17×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
NWN
NWN
Operating Cash FlowLast quarter
$-14.2M
$3.3M
Free Cash FlowOCF − Capex
$-14.3M
$-131.0M
FCF MarginFCF / Revenue
-7.1%
-33.2%
Capex IntensityCapex / Revenue
0.1%
34.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$-197.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
NWN
NWN
Q4 25
$-14.2M
$3.3M
Q3 25
$108.5M
$-15.9M
Q2 25
$4.4M
$102.2M
Q1 25
$-53.4M
$179.6M
Q4 24
$19.4M
$-19.4M
Q3 24
$34.1M
$-26.4M
Q2 24
$-8.3M
$121.0M
Q1 24
$-133.0M
$125.0M
Free Cash Flow
APLS
APLS
NWN
NWN
Q4 25
$-14.3M
$-131.0M
Q3 25
$108.3M
$-125.9M
Q2 25
$4.4M
$-18.3M
Q1 25
$-53.4M
$77.4M
Q4 24
$19.3M
$-119.6M
Q3 24
$-121.7M
Q2 24
$-8.4M
$4.3M
Q1 24
$-133.3M
$42.8M
FCF Margin
APLS
APLS
NWN
NWN
Q4 25
-7.1%
-33.2%
Q3 25
23.6%
-76.4%
Q2 25
2.5%
-7.8%
Q1 25
-32.0%
15.7%
Q4 24
9.1%
-32.2%
Q3 24
-88.9%
Q2 24
-4.2%
2.0%
Q1 24
-77.3%
9.9%
Capex Intensity
APLS
APLS
NWN
NWN
Q4 25
0.1%
34.1%
Q3 25
0.0%
66.8%
Q2 25
0.0%
51.0%
Q1 25
0.0%
20.7%
Q4 24
0.0%
27.0%
Q3 24
0.0%
69.6%
Q2 24
0.0%
55.1%
Q1 24
0.2%
19.0%
Cash Conversion
APLS
APLS
NWN
NWN
Q4 25
Q3 25
0.50×
Q2 25
Q1 25
2.04×
Q4 24
Q3 24
Q2 24
Q1 24
1.96×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

NWN
NWN

NWN Gas Utility$341.4M87%
Alternativerevenue$27.2M7%
Si Energy Gas Utility$20.0M5%
NW Natural Other$6.9M2%

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