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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and TRUPANION, INC. (TRUP). Click either name above to swap in a different company.

TRUPANION, INC. is the larger business by last-quarter revenue ($376.9M vs $199.9M, roughly 1.9× Apellis Pharmaceuticals, Inc.). On growth, TRUPANION, INC. posted the faster year-over-year revenue change (11.7% vs -5.9%). TRUPANION, INC. produced more free cash flow last quarter ($25.3M vs $-14.3M). Over the past eight quarters, TRUPANION, INC.'s revenue compounded faster (11.0% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

Trupanion, Inc. is a pet insurance provider headquartered in Seattle, Washington. Established in 1998, Trupanion operates across the United States, Canada, Australia, and Puerto Rico. The company offers coverage for pets and is self-underwritten by the American Pet Insurance Company (APIC).

APLS vs TRUP — Head-to-Head

Bigger by revenue
TRUP
TRUP
1.9× larger
TRUP
$376.9M
$199.9M
APLS
Growing faster (revenue YoY)
TRUP
TRUP
+17.7% gap
TRUP
11.7%
-5.9%
APLS
More free cash flow
TRUP
TRUP
$39.6M more FCF
TRUP
$25.3M
$-14.3M
APLS
Faster 2-yr revenue CAGR
TRUP
TRUP
Annualised
TRUP
11.0%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
TRUP
TRUP
Revenue
$199.9M
$376.9M
Net Profit
$-59.0M
Gross Margin
17.3%
Operating Margin
-25.6%
1.9%
Net Margin
-29.5%
Revenue YoY
-5.9%
11.7%
Net Profit YoY
-62.2%
EPS (diluted)
$-0.40
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
TRUP
TRUP
Q4 25
$199.9M
$376.9M
Q3 25
$458.6M
$366.9M
Q2 25
$178.5M
$353.6M
Q1 25
$166.8M
$342.0M
Q4 24
$212.5M
$337.3M
Q3 24
$196.8M
$327.5M
Q2 24
$199.7M
$314.8M
Q1 24
$172.3M
$306.1M
Net Profit
APLS
APLS
TRUP
TRUP
Q4 25
$-59.0M
Q3 25
$215.7M
Q2 25
$-42.2M
Q1 25
$-92.2M
Q4 24
$-36.4M
Q3 24
$-57.4M
Q2 24
$-37.7M
Q1 24
$-66.4M
Gross Margin
APLS
APLS
TRUP
TRUP
Q4 25
17.3%
Q3 25
16.4%
Q2 25
15.5%
Q1 25
14.9%
Q4 24
15.7%
Q3 24
15.1%
Q2 24
12.8%
Q1 24
11.8%
Operating Margin
APLS
APLS
TRUP
TRUP
Q4 25
-25.6%
1.9%
Q3 25
48.7%
1.6%
Q2 25
-18.6%
0.7%
Q1 25
-50.0%
-0.4%
Q4 24
-12.3%
0.1%
Q3 24
-24.0%
0.5%
Q2 24
-14.7%
-1.7%
Q1 24
-36.0%
-2.0%
Net Margin
APLS
APLS
TRUP
TRUP
Q4 25
-29.5%
Q3 25
47.0%
Q2 25
-23.6%
Q1 25
-55.3%
Q4 24
-17.1%
Q3 24
-29.2%
Q2 24
-18.9%
Q1 24
-38.5%
EPS (diluted)
APLS
APLS
TRUP
TRUP
Q4 25
$-0.40
$0.13
Q3 25
$1.67
$0.13
Q2 25
$-0.33
$0.22
Q1 25
$-0.74
$-0.03
Q4 24
$-0.30
$0.04
Q3 24
$-0.46
$0.03
Q2 24
$-0.30
$-0.14
Q1 24
$-0.54
$-0.16

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
TRUP
TRUP
Cash + ST InvestmentsLiquidity on hand
$466.2M
$370.7M
Total DebtLower is stronger
$101.8M
Stockholders' EquityBook value
$370.1M
$383.9M
Total Assets
$1.1B
$915.0M
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
TRUP
TRUP
Q4 25
$466.2M
$370.7M
Q3 25
$479.2M
$348.5M
Q2 25
$370.0M
$319.6M
Q1 25
$358.4M
$321.8M
Q4 24
$411.3M
$307.4M
Q3 24
$396.9M
$293.1M
Q2 24
$360.1M
$277.2M
Q1 24
$325.9M
$275.2M
Total Debt
APLS
APLS
TRUP
TRUP
Q4 25
$101.8M
Q3 25
Q2 25
Q1 25
Q4 24
$127.5M
Q3 24
Q2 24
Q1 24
$93.1M
Stockholders' Equity
APLS
APLS
TRUP
TRUP
Q4 25
$370.1M
$383.9M
Q3 25
$401.2M
$368.6M
Q2 25
$156.3M
$355.5M
Q1 25
$164.2M
$333.7M
Q4 24
$228.5M
$323.3M
Q3 24
$237.1M
$320.2M
Q2 24
$264.3M
$305.8M
Q1 24
$266.7M
$303.4M
Total Assets
APLS
APLS
TRUP
TRUP
Q4 25
$1.1B
$915.0M
Q3 25
$1.1B
$880.2M
Q2 25
$821.4M
$847.8M
Q1 25
$807.3M
$837.2M
Q4 24
$885.1M
$806.9M
Q3 24
$901.9M
$816.1M
Q2 24
$904.5M
$795.9M
Q1 24
$831.9M
$789.5M
Debt / Equity
APLS
APLS
TRUP
TRUP
Q4 25
0.27×
Q3 25
Q2 25
Q1 25
Q4 24
0.39×
Q3 24
Q2 24
Q1 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
TRUP
TRUP
Operating Cash FlowLast quarter
$-14.2M
$29.3M
Free Cash FlowOCF − Capex
$-14.3M
$25.3M
FCF MarginFCF / Revenue
-7.1%
6.7%
Capex IntensityCapex / Revenue
0.1%
1.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$75.4M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
TRUP
TRUP
Q4 25
$-14.2M
$29.3M
Q3 25
$108.5M
$29.2M
Q2 25
$4.4M
$15.0M
Q1 25
$-53.4M
$16.0M
Q4 24
$19.4M
$23.7M
Q3 24
$34.1M
$15.3M
Q2 24
$-8.3M
$6.9M
Q1 24
$-133.0M
$2.4M
Free Cash Flow
APLS
APLS
TRUP
TRUP
Q4 25
$-14.3M
$25.3M
Q3 25
$108.3M
$23.9M
Q2 25
$4.4M
$12.0M
Q1 25
$-53.4M
$14.0M
Q4 24
$19.3M
$21.8M
Q3 24
$13.4M
Q2 24
$-8.4M
$4.0M
Q1 24
$-133.3M
$-631.0K
FCF Margin
APLS
APLS
TRUP
TRUP
Q4 25
-7.1%
6.7%
Q3 25
23.6%
6.5%
Q2 25
2.5%
3.4%
Q1 25
-32.0%
4.1%
Q4 24
9.1%
6.5%
Q3 24
4.1%
Q2 24
-4.2%
1.3%
Q1 24
-77.3%
-0.2%
Capex Intensity
APLS
APLS
TRUP
TRUP
Q4 25
0.1%
1.0%
Q3 25
0.0%
1.4%
Q2 25
0.0%
0.8%
Q1 25
0.0%
0.6%
Q4 24
0.0%
0.6%
Q3 24
0.0%
0.6%
Q2 24
0.0%
0.9%
Q1 24
0.2%
1.0%
Cash Conversion
APLS
APLS
TRUP
TRUP
Q4 25
Q3 25
0.50×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

TRUP
TRUP

Subscriptionbusiness$261.4M69%
Other$115.4M31%

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