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Side-by-side financial comparison of ARDELYX, INC. (ARDX) and ENTERPRISE FINANCIAL SERVICES CORP (EFSC). Click either name above to swap in a different company.

ENTERPRISE FINANCIAL SERVICES CORP is the larger business by last-quarter revenue ($185.2M vs $94.5M, roughly 2.0× ARDELYX, INC.). ENTERPRISE FINANCIAL SERVICES CORP runs the higher net margin — 26.6% vs -39.8%, a 66.5% gap on every dollar of revenue. Over the past eight quarters, ARDELYX, INC.'s revenue compounded faster (13.6% CAGR vs 9.0%).

Ardelyx, Inc. is a commercial-stage biopharmaceutical firm developing and commercializing innovative therapies for gastrointestinal, cardiorenal and metabolic diseases with high unmet medical needs. Its lead product is approved in the US for irritable bowel syndrome with constipation, and it holds a robust pipeline of early and late-stage drug candidates.

The Hewlett Packard Enterprise Company (HPE) is an American multinational information technology company based in Spring, Texas. It is a business-focused organization which works in servers, storage, networking, containerization software and consulting and support. HPE was ranked No. 107 in the 2018 Fortune 500 list of the largest United States corporations by total revenue.

ARDX vs EFSC — Head-to-Head

Bigger by revenue
EFSC
EFSC
2.0× larger
EFSC
$185.2M
$94.5M
ARDX
Higher net margin
EFSC
EFSC
66.5% more per $
EFSC
26.6%
-39.8%
ARDX
Faster 2-yr revenue CAGR
ARDX
ARDX
Annualised
ARDX
13.6%
9.0%
EFSC

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
ARDX
ARDX
EFSC
EFSC
Revenue
$94.5M
$185.2M
Net Profit
$-37.6M
$49.4M
Gross Margin
Operating Margin
Net Margin
-39.8%
26.6%
Revenue YoY
27.5%
Net Profit YoY
-1.2%
EPS (diluted)
$-0.15
$1.30

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARDX
ARDX
EFSC
EFSC
Q1 26
$94.5M
$185.2M
Q4 25
$125.2M
$193.6M
Q3 25
$110.3M
$206.9M
Q2 25
$97.7M
$173.4M
Q1 25
$74.1M
$166.0M
Q4 24
$116.1M
$167.0M
Q3 24
$98.2M
$164.9M
Q2 24
$73.2M
$156.0M
Net Profit
ARDX
ARDX
EFSC
EFSC
Q1 26
$-37.6M
$49.4M
Q4 25
$-407.0K
$54.8M
Q3 25
$-969.0K
$45.2M
Q2 25
$-19.1M
$51.4M
Q1 25
$-41.1M
$50.0M
Q4 24
$4.6M
$48.8M
Q3 24
$-809.0K
$50.6M
Q2 24
$-16.5M
$45.4M
Gross Margin
ARDX
ARDX
EFSC
EFSC
Q1 26
Q4 25
91.3%
Q3 25
96.4%
Q2 25
87.3%
Q1 25
83.4%
Q4 24
84.3%
Q3 24
84.0%
Q2 24
87.1%
Operating Margin
ARDX
ARDX
EFSC
EFSC
Q1 26
Q4 25
4.1%
Q3 25
4.2%
42.9%
Q2 25
-14.7%
37.0%
Q1 25
-49.0%
36.8%
Q4 24
7.0%
Q3 24
2.3%
38.1%
Q2 24
-18.6%
36.7%
Net Margin
ARDX
ARDX
EFSC
EFSC
Q1 26
-39.8%
26.6%
Q4 25
-0.3%
28.3%
Q3 25
-0.9%
21.9%
Q2 25
-19.5%
29.6%
Q1 25
-55.5%
30.1%
Q4 24
4.0%
29.2%
Q3 24
-0.8%
30.7%
Q2 24
-22.5%
29.1%
EPS (diluted)
ARDX
ARDX
EFSC
EFSC
Q1 26
$-0.15
$1.30
Q4 25
$-0.01
$1.45
Q3 25
$0.00
$1.19
Q2 25
$-0.08
$1.36
Q1 25
$-0.17
$1.31
Q4 24
$0.01
$1.27
Q3 24
$0.00
$1.32
Q2 24
$-0.07
$1.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARDX
ARDX
EFSC
EFSC
Cash + ST InvestmentsLiquidity on hand
$238.1M
Total DebtLower is stronger
$203.5M
Stockholders' EquityBook value
$148.6M
$2.1B
Total Assets
$504.5M
$17.3B
Debt / EquityLower = less leverage
1.37×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARDX
ARDX
EFSC
EFSC
Q1 26
$238.1M
Q4 25
$68.0M
Q3 25
$42.7M
Q2 25
$90.0M
Q1 25
$30.8M
Q4 24
$64.9M
Q3 24
$47.4M
Q2 24
$41.9M
Total Debt
ARDX
ARDX
EFSC
EFSC
Q1 26
$203.5M
Q4 25
$202.8M
Q3 25
$202.1M
Q2 25
$201.4M
Q1 25
$151.3M
Q4 24
$150.9M
Q3 24
$100.7M
Q2 24
$100.2M
Stockholders' Equity
ARDX
ARDX
EFSC
EFSC
Q1 26
$148.6M
$2.1B
Q4 25
$166.9M
$2.0B
Q3 25
$154.3M
$2.0B
Q2 25
$139.5M
$1.9B
Q1 25
$145.7M
$1.9B
Q4 24
$173.3M
$1.8B
Q3 24
$158.3M
$1.8B
Q2 24
$147.0M
$1.8B
Total Assets
ARDX
ARDX
EFSC
EFSC
Q1 26
$504.5M
$17.3B
Q4 25
$501.6M
$17.3B
Q3 25
$486.2M
$16.4B
Q2 25
$466.8M
$16.1B
Q1 25
$410.2M
$15.7B
Q4 24
$435.8M
$15.6B
Q3 24
$367.9M
$15.0B
Q2 24
$343.5M
$14.6B
Debt / Equity
ARDX
ARDX
EFSC
EFSC
Q1 26
1.37×
Q4 25
1.21×
Q3 25
1.31×
Q2 25
1.44×
Q1 25
1.04×
Q4 24
0.87×
Q3 24
0.64×
Q2 24
0.68×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ARDX
ARDX

IBSRELA$70.1M74%
XPHOZAH$23.3M25%
Non-cash royalty revenue related to the sale of future royalties$695.0K1%
Product supply revenue$354.0K0%

EFSC
EFSC

Net Interest Income$166.1M90%
Noninterest Income$19.1M10%

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