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Side-by-side financial comparison of ARROWHEAD PHARMACEUTICALS, INC. (ARWR) and Grand Canyon Education, Inc. (LOPE). Click either name above to swap in a different company.

Grand Canyon Education, Inc. is the larger business by last-quarter revenue ($308.1M vs $264.0M, roughly 1.2× ARROWHEAD PHARMACEUTICALS, INC.). Grand Canyon Education, Inc. runs the higher net margin — 28.1% vs 11.7%, a 16.5% gap on every dollar of revenue. On growth, ARROWHEAD PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (10461.3% vs 5.3%). Grand Canyon Education, Inc. produced more free cash flow last quarter ($122.9M vs $11.3M).

Arrowhead Pharmaceuticals, Inc. is a publicly traded biopharmaceutical company based in Pasadena, California. Arrowhead's products in development act through RNA interference (RNAi) mechanisms of action. The company focuses on treatments for hepatitis B, liver disease associated with alpha 1-antitrypsin deficiency and cardiovascular disease.

Grand Canyon Education, Inc. (GCE) is an American for-profit corporation that provides services to universities, specializing in program development, online education, and operational support. Formerly affiliated with Grand Canyon University (GCU), a Christian university in Arizona, GCE became a separate publicly traded company in 2008.

ARWR vs LOPE — Head-to-Head

Bigger by revenue
LOPE
LOPE
1.2× larger
LOPE
$308.1M
$264.0M
ARWR
Growing faster (revenue YoY)
ARWR
ARWR
+10456.0% gap
ARWR
10461.3%
5.3%
LOPE
Higher net margin
LOPE
LOPE
16.5% more per $
LOPE
28.1%
11.7%
ARWR
More free cash flow
LOPE
LOPE
$111.5M more FCF
LOPE
$122.9M
$11.3M
ARWR

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ARWR
ARWR
LOPE
LOPE
Revenue
$264.0M
$308.1M
Net Profit
$30.8M
$86.7M
Gross Margin
Operating Margin
15.5%
35.1%
Net Margin
11.7%
28.1%
Revenue YoY
10461.3%
5.3%
Net Profit YoY
117.8%
5.9%
EPS (diluted)
$0.22
$3.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARWR
ARWR
LOPE
LOPE
Q4 25
$264.0M
$308.1M
Q3 25
$261.1M
Q2 25
$247.5M
Q1 25
$289.3M
Q4 24
$292.6M
Q3 24
$238.3M
Q2 24
$227.5M
Q1 24
$274.7M
Net Profit
ARWR
ARWR
LOPE
LOPE
Q4 25
$30.8M
$86.7M
Q3 25
$16.3M
Q2 25
$41.5M
Q1 25
$71.6M
Q4 24
$81.9M
Q3 24
$41.5M
Q2 24
$34.9M
Q1 24
$68.0M
Operating Margin
ARWR
ARWR
LOPE
LOPE
Q4 25
15.5%
35.1%
Q3 25
6.9%
Q2 25
20.9%
Q1 25
30.4%
Q4 24
34.2%
Q3 24
20.2%
Q2 24
18.8%
Q1 24
30.8%
Net Margin
ARWR
ARWR
LOPE
LOPE
Q4 25
11.7%
28.1%
Q3 25
6.2%
Q2 25
16.8%
Q1 25
24.8%
Q4 24
28.0%
Q3 24
17.4%
Q2 24
15.3%
Q1 24
24.8%
EPS (diluted)
ARWR
ARWR
LOPE
LOPE
Q4 25
$0.22
$3.13
Q3 25
$0.58
Q2 25
$1.48
Q1 25
$2.52
Q4 24
$2.83
Q3 24
$1.42
Q2 24
$1.19
Q1 24
$2.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARWR
ARWR
LOPE
LOPE
Cash + ST InvestmentsLiquidity on hand
$715.0M
$111.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$568.4M
$746.9M
Total Assets
$1.6B
$992.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARWR
ARWR
LOPE
LOPE
Q4 25
$715.0M
$111.8M
Q3 25
$97.3M
Q2 25
$192.3M
Q1 25
$144.5M
Q4 24
$324.6M
Q3 24
$263.6M
Q2 24
$241.3M
Q1 24
$196.2M
Stockholders' Equity
ARWR
ARWR
LOPE
LOPE
Q4 25
$568.4M
$746.9M
Q3 25
$758.0M
Q2 25
$778.0M
Q1 25
$780.7M
Q4 24
$783.9M
Q3 24
$764.1M
Q2 24
$759.2M
Q1 24
$759.4M
Total Assets
ARWR
ARWR
LOPE
LOPE
Q4 25
$1.6B
$992.3M
Q3 25
$1.0B
Q2 25
$1.0B
Q1 25
$1.0B
Q4 24
$1.0B
Q3 24
$992.9M
Q2 24
$992.7M
Q1 24
$1.0B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ARWR
ARWR
LOPE
LOPE
Operating Cash FlowLast quarter
$13.5M
$130.5M
Free Cash FlowOCF − Capex
$11.3M
$122.9M
FCF MarginFCF / Revenue
4.3%
39.9%
Capex IntensityCapex / Revenue
0.8%
2.5%
Cash ConversionOCF / Net Profit
0.44×
1.50×
TTM Free Cash FlowTrailing 4 quarters
$238.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ARWR
ARWR
LOPE
LOPE
Q4 25
$13.5M
$130.5M
Q3 25
$-48.6M
Q2 25
$124.0M
Q1 25
$67.6M
Q4 24
$135.8M
Q3 24
$-29.4M
Q2 24
$98.6M
Q1 24
$85.0M
Free Cash Flow
ARWR
ARWR
LOPE
LOPE
Q4 25
$11.3M
$122.9M
Q3 25
$-58.3M
Q2 25
$115.4M
Q1 25
$58.7M
Q4 24
$126.1M
Q3 24
$-39.0M
Q2 24
$89.6M
Q1 24
$76.0M
FCF Margin
ARWR
ARWR
LOPE
LOPE
Q4 25
4.3%
39.9%
Q3 25
-22.3%
Q2 25
46.6%
Q1 25
20.3%
Q4 24
43.1%
Q3 24
-16.3%
Q2 24
39.4%
Q1 24
27.7%
Capex Intensity
ARWR
ARWR
LOPE
LOPE
Q4 25
0.8%
2.5%
Q3 25
3.7%
Q2 25
3.5%
Q1 25
3.1%
Q4 24
3.3%
Q3 24
4.0%
Q2 24
3.9%
Q1 24
3.3%
Cash Conversion
ARWR
ARWR
LOPE
LOPE
Q4 25
0.44×
1.50×
Q3 25
-2.99×
Q2 25
2.98×
Q1 25
0.94×
Q4 24
1.66×
Q3 24
-0.71×
Q2 24
2.83×
Q1 24
1.25×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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