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Side-by-side financial comparison of ARROWHEAD PHARMACEUTICALS, INC. (ARWR) and MEDICAL PROPERTIES TRUST INC (MPW). Click either name above to swap in a different company.

MEDICAL PROPERTIES TRUST INC is the larger business by last-quarter revenue ($270.3M vs $264.0M, roughly 1.0× ARROWHEAD PHARMACEUTICALS, INC.). ARROWHEAD PHARMACEUTICALS, INC. runs the higher net margin — 11.7% vs 6.5%, a 5.2% gap on every dollar of revenue. On growth, ARROWHEAD PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (10461.3% vs 16.6%).

Arrowhead Pharmaceuticals, Inc. is a publicly traded biopharmaceutical company based in Pasadena, California. Arrowhead's products in development act through RNA interference (RNAi) mechanisms of action. The company focuses on treatments for hepatitis B, liver disease associated with alpha 1-antitrypsin deficiency and cardiovascular disease.

Medical Properties Trust, Inc. (MPT) is an international real estate investment trust (REIT) based in Birmingham, Alabama that purchases and invests in healthcare facilities and for-profit healthcare holding companies, primarily in the United States and Europe. Their property acquisitions often come in the form of sale-leaseback agreements, in which the original property owner sells the property to MPT and becomes their tenant. MPT's tenants are generally subject to long-term triple net lease...

ARWR vs MPW — Head-to-Head

Bigger by revenue
MPW
MPW
1.0× larger
MPW
$270.3M
$264.0M
ARWR
Growing faster (revenue YoY)
ARWR
ARWR
+10444.7% gap
ARWR
10461.3%
16.6%
MPW
Higher net margin
ARWR
ARWR
5.2% more per $
ARWR
11.7%
6.5%
MPW

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ARWR
ARWR
MPW
MPW
Revenue
$264.0M
$270.3M
Net Profit
$30.8M
$17.6M
Gross Margin
95.8%
Operating Margin
15.5%
9.7%
Net Margin
11.7%
6.5%
Revenue YoY
10461.3%
16.6%
Net Profit YoY
117.8%
104.3%
EPS (diluted)
$0.22
$0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARWR
ARWR
MPW
MPW
Q4 25
$264.0M
$270.3M
Q3 25
$237.5M
Q2 25
$240.4M
Q1 25
$223.8M
Q4 24
$231.8M
Q3 24
$225.8M
Q2 24
$266.6M
Q1 24
$271.3M
Net Profit
ARWR
ARWR
MPW
MPW
Q4 25
$30.8M
$17.6M
Q3 25
$-77.7M
Q2 25
$-98.4M
Q1 25
$-118.3M
Q4 24
$-412.3M
Q3 24
$-801.2M
Q2 24
$-320.6M
Q1 24
$-875.6M
Gross Margin
ARWR
ARWR
MPW
MPW
Q4 25
95.8%
Q3 25
Q2 25
91.8%
Q1 25
63.6%
Q4 24
90.9%
Q3 24
96.5%
Q2 24
98.4%
Q1 24
84.9%
Operating Margin
ARWR
ARWR
MPW
MPW
Q4 25
15.5%
9.7%
Q3 25
-28.0%
Q2 25
-36.7%
Q1 25
-48.5%
Q4 24
-173.7%
Q3 24
-350.7%
Q2 24
-114.5%
Q1 24
-318.6%
Net Margin
ARWR
ARWR
MPW
MPW
Q4 25
11.7%
6.5%
Q3 25
-32.7%
Q2 25
-40.9%
Q1 25
-52.8%
Q4 24
-177.8%
Q3 24
-354.8%
Q2 24
-120.3%
Q1 24
-322.7%
EPS (diluted)
ARWR
ARWR
MPW
MPW
Q4 25
$0.22
$0.03
Q3 25
$-0.13
Q2 25
$-0.16
Q1 25
$-0.20
Q4 24
$-0.68
Q3 24
$-1.34
Q2 24
$-0.54
Q1 24
$-1.46

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARWR
ARWR
MPW
MPW
Cash + ST InvestmentsLiquidity on hand
$715.0M
$540.9M
Total DebtLower is stronger
$9.7B
Stockholders' EquityBook value
$568.4M
$4.6B
Total Assets
$1.6B
$15.0B
Debt / EquityLower = less leverage
2.11×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARWR
ARWR
MPW
MPW
Q4 25
$715.0M
$540.9M
Q3 25
$396.6M
Q2 25
$509.8M
Q1 25
$673.5M
Q4 24
$332.3M
Q3 24
$275.6M
Q2 24
$606.5M
Q1 24
$224.3M
Total Debt
ARWR
ARWR
MPW
MPW
Q4 25
$9.7B
Q3 25
$9.6B
Q2 25
$9.6B
Q1 25
$9.5B
Q4 24
$8.8B
Q3 24
$9.2B
Q2 24
$9.4B
Q1 24
$10.1B
Stockholders' Equity
ARWR
ARWR
MPW
MPW
Q4 25
$568.4M
$4.6B
Q3 25
$4.7B
Q2 25
$4.8B
Q1 25
$4.8B
Q4 24
$4.8B
Q3 24
$5.4B
Q2 24
$6.2B
Q1 24
$6.7B
Total Assets
ARWR
ARWR
MPW
MPW
Q4 25
$1.6B
$15.0B
Q3 25
$14.9B
Q2 25
$15.2B
Q1 25
$14.9B
Q4 24
$14.3B
Q3 24
$15.2B
Q2 24
$16.2B
Q1 24
$17.3B
Debt / Equity
ARWR
ARWR
MPW
MPW
Q4 25
2.11×
Q3 25
2.06×
Q2 25
2.00×
Q1 25
1.99×
Q4 24
1.83×
Q3 24
1.69×
Q2 24
1.51×
Q1 24
1.51×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ARWR
ARWR
MPW
MPW
Operating Cash FlowLast quarter
$13.5M
$230.8M
Free Cash FlowOCF − Capex
$11.3M
FCF MarginFCF / Revenue
4.3%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
0.44×
13.11×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ARWR
ARWR
MPW
MPW
Q4 25
$13.5M
$230.8M
Q3 25
$18.6M
Q2 25
$51.7M
Q1 25
$384.0K
Q4 24
$245.5M
Q3 24
$59.2M
Q2 24
$35.3M
Q1 24
$74.3M
Free Cash Flow
ARWR
ARWR
MPW
MPW
Q4 25
$11.3M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
ARWR
ARWR
MPW
MPW
Q4 25
4.3%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
ARWR
ARWR
MPW
MPW
Q4 25
0.8%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Cash Conversion
ARWR
ARWR
MPW
MPW
Q4 25
0.44×
13.11×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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