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Side-by-side financial comparison of Assertio Holdings, Inc. (ASRT) and Avidity Biosciences, Inc. (RNA). Click either name above to swap in a different company.

Assertio Holdings, Inc. is the larger business by last-quarter revenue ($13.5M vs $12.5M, roughly 1.1× Avidity Biosciences, Inc.). On growth, Avidity Biosciences, Inc. posted the faster year-over-year revenue change (434.0% vs -57.9%). Over the past eight quarters, Avidity Biosciences, Inc.'s revenue compounded faster (138.5% CAGR vs -35.4%).

Assertio Therapeutics, Inc. is an American specialty pharmaceutical company. It mainly markets products for treatment in neurology, pain and diseases of the central nervous system. Depomed was founded in 1995 and is headquartered in Newark, California. It is a publicly traded company on NASDAQ, with several products approved by the United States Food and Drug Administration (FDA). On August 15, 2018, the company announced its name change from Depomed, Inc., to Assertio Therapeutics, Inc. As o...

Eli Lilly and Company, doing business as Lilly, is an American multinational pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by Eli Lilly, a pharmaceutical chemist and Union army veteran during the American Civil War for whom the company was later named.

ASRT vs RNA — Head-to-Head

Bigger by revenue
ASRT
ASRT
1.1× larger
ASRT
$13.5M
$12.5M
RNA
Growing faster (revenue YoY)
RNA
RNA
+491.9% gap
RNA
434.0%
-57.9%
ASRT
Faster 2-yr revenue CAGR
RNA
RNA
Annualised
RNA
138.5%
-35.4%
ASRT

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
ASRT
ASRT
RNA
RNA
Revenue
$13.5M
$12.5M
Net Profit
$-174.4M
Gross Margin
Operating Margin
-86.7%
-1513.5%
Net Margin
-1398.3%
Revenue YoY
-57.9%
434.0%
Net Profit YoY
-117.0%
EPS (diluted)
$-4.54
$-1.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASRT
ASRT
RNA
RNA
Q4 25
$13.5M
Q3 25
$49.5M
$12.5M
Q2 25
$29.2M
$3.8M
Q1 25
$26.5M
$1.6M
Q4 24
$32.2M
$3.0M
Q3 24
$29.2M
$2.3M
Q2 24
$31.1M
$2.0M
Q1 24
$32.4M
$3.5M
Net Profit
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
$11.4M
$-174.4M
Q2 25
$-16.4M
$-157.3M
Q1 25
$-13.5M
$-115.8M
Q4 24
$-102.3M
Q3 24
$-2.9M
$-80.4M
Q2 24
$-3.7M
$-70.8M
Q1 24
$-4.5M
$-68.9M
Operating Margin
ASRT
ASRT
RNA
RNA
Q4 25
-86.7%
Q3 25
23.2%
-1513.5%
Q2 25
-27.5%
-4448.7%
Q1 25
-50.0%
-8360.9%
Q4 24
-41.9%
-4069.6%
Q3 24
-10.4%
-4200.9%
Q2 24
-11.6%
-4040.4%
Q1 24
-13.4%
-2178.6%
Net Margin
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
23.1%
-1398.3%
Q2 25
-56.0%
-4089.3%
Q1 25
-51.1%
-7360.0%
Q4 24
-3439.5%
Q3 24
-10.0%
-3441.7%
Q2 24
-11.8%
-3461.8%
Q1 24
-13.9%
-1943.4%
EPS (diluted)
ASRT
ASRT
RNA
RNA
Q4 25
$-4.54
Q3 25
$0.11
$-1.27
Q2 25
$-0.17
$-1.21
Q1 25
$-0.14
$-0.90
Q4 24
$-3.28
$-0.80
Q3 24
$-0.03
$-0.65
Q2 24
$-0.04
$-0.65
Q1 24
$-0.05
$-0.79

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASRT
ASRT
RNA
RNA
Cash + ST InvestmentsLiquidity on hand
$63.4M
$350.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$94.0M
$1.9B
Total Assets
$267.0M
$2.1B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASRT
ASRT
RNA
RNA
Q4 25
$63.4M
Q3 25
$93.4M
$350.2M
Q2 25
$98.2M
$243.9M
Q1 25
$87.3M
$254.2M
Q4 24
$100.1M
$219.9M
Q3 24
$88.6M
$370.2M
Q2 24
$88.4M
$575.8M
Q1 24
$80.7M
$471.4M
Total Debt
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
$38.6M
Stockholders' Equity
ASRT
ASRT
RNA
RNA
Q4 25
$94.0M
Q3 25
$105.8M
$1.9B
Q2 25
$93.3M
$1.2B
Q1 25
$108.5M
$1.3B
Q4 24
$121.1M
$1.4B
Q3 24
$130.5M
$1.5B
Q2 24
$132.2M
$1.2B
Q1 24
$134.5M
$830.9M
Total Assets
ASRT
ASRT
RNA
RNA
Q4 25
$267.0M
Q3 25
$319.8M
$2.1B
Q2 25
$273.8M
$1.4B
Q1 25
$286.4M
$1.5B
Q4 24
$284.7M
$1.6B
Q3 24
$276.0M
$1.6B
Q2 24
$279.4M
$1.3B
Q1 24
$282.0M
$951.5M
Debt / Equity
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
0.29×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASRT
ASRT
RNA
RNA
Operating Cash FlowLast quarter
$-30.0M
$-156.2M
Free Cash FlowOCF − Capex
$-156.9M
FCF MarginFCF / Revenue
-1257.6%
Capex IntensityCapex / Revenue
5.7%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-592.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASRT
ASRT
RNA
RNA
Q4 25
$-30.0M
Q3 25
$-4.8M
$-156.2M
Q2 25
$19.1M
$-199.7M
Q1 25
$-12.5M
$-124.8M
Q4 24
$11.5M
$-99.9M
Q3 24
$-35.0K
$-65.6M
Q2 24
$7.4M
$-65.0M
Q1 24
$7.5M
$-70.4M
Free Cash Flow
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
$-156.9M
Q2 25
$-203.0M
Q1 25
$-128.6M
Q4 24
$-103.8M
Q3 24
$-67.3M
Q2 24
$-65.5M
Q1 24
$-71.3M
FCF Margin
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
-1257.6%
Q2 25
-5277.1%
Q1 25
-8174.3%
Q4 24
-3491.0%
Q3 24
-2881.8%
Q2 24
-3204.6%
Q1 24
-2012.3%
Capex Intensity
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
5.7%
Q2 25
86.9%
Q1 25
238.6%
Q4 24
131.7%
Q3 24
0.0%
72.9%
Q2 24
26.0%
Q1 24
25.8%
Cash Conversion
ASRT
ASRT
RNA
RNA
Q4 25
Q3 25
-0.42×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ASRT
ASRT

Products$12.8M95%
Other$719.0K5%

RNA
RNA

Segment breakdown not available.

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