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Side-by-side financial comparison of American Express (AXP) and TriSalus Life Sciences, Inc. (TLSI). Click either name above to swap in a different company.

American Express is the larger business by last-quarter revenue ($18.9M vs $13.2M, roughly 1.4× TriSalus Life Sciences, Inc.). American Express runs the higher net margin — 15.7% vs -73.9%, a 89.6% gap on every dollar of revenue. On growth, TriSalus Life Sciences, Inc. posted the faster year-over-year revenue change (59.8% vs 11.4%). Over the past eight quarters, TriSalus Life Sciences, Inc.'s revenue compounded faster (43.0% CAGR vs -95.6%).

American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...

TriSalus Life Sciences, Inc. is a clinical-stage biotechnology company focused on advancing immuno-oncology and interventional oncology solutions. It develops proprietary targeted drug delivery technologies designed to improve treatment efficacy for patients with liver, pancreatic and other hard-to-treat solid tumors, primarily operating in North American markets via partnerships with clinical care and research institutions.

AXP vs TLSI — Head-to-Head

Bigger by revenue
AXP
AXP
1.4× larger
AXP
$18.9M
$13.2M
TLSI
Growing faster (revenue YoY)
TLSI
TLSI
+48.4% gap
TLSI
59.8%
11.4%
AXP
Higher net margin
AXP
AXP
89.6% more per $
AXP
15.7%
-73.9%
TLSI
Faster 2-yr revenue CAGR
TLSI
TLSI
Annualised
TLSI
43.0%
-95.6%
AXP

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
AXP
AXP
TLSI
TLSI
Revenue
$18.9M
$13.2M
Net Profit
$3.0M
$-9.8M
Gross Margin
86.7%
Operating Margin
-24.8%
Net Margin
15.7%
-73.9%
Revenue YoY
11.4%
59.8%
Net Profit YoY
15.0%
3.5%
EPS (diluted)
$-0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXP
AXP
TLSI
TLSI
Q1 26
$18.9M
Q4 25
$10.9B
$13.2M
Q3 25
$10.4B
$11.6M
Q2 25
$10.3B
$11.2M
Q1 25
$9.6B
$9.2M
Q4 24
$10.0B
$8.3M
Q3 24
$9.7B
$7.3M
Q2 24
$9.8B
$7.4M
Net Profit
AXP
AXP
TLSI
TLSI
Q1 26
$3.0M
Q4 25
$2.5B
$-9.8M
Q3 25
$2.9B
$-10.8M
Q2 25
$2.9B
$-8.3M
Q1 25
$2.6B
$-10.4M
Q4 24
$2.2B
$-10.1M
Q3 24
$2.5B
$-2.4M
Q2 24
$3.0B
$-4.3M
Gross Margin
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
86.7%
Q3 25
83.5%
Q2 25
83.9%
Q1 25
83.7%
Q4 24
85.3%
Q3 24
86.3%
Q2 24
87.6%
Operating Margin
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
28.2%
-24.8%
Q3 25
36.7%
-77.9%
Q2 25
34.4%
-65.4%
Q1 25
34.6%
-79.9%
Q4 24
27.7%
-91.8%
Q3 24
33.0%
-118.9%
Q2 24
38.6%
-111.0%
Net Margin
AXP
AXP
TLSI
TLSI
Q1 26
15.7%
Q4 25
22.5%
-73.9%
Q3 25
27.9%
-93.5%
Q2 25
28.0%
-73.9%
Q1 25
26.8%
-113.2%
Q4 24
21.8%
-122.4%
Q3 24
25.8%
-32.6%
Q2 24
30.7%
-58.8%
EPS (diluted)
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
$3.52
$-0.22
Q3 25
$4.14
$-0.96
Q2 25
$4.08
$-0.27
Q1 25
$3.64
$-0.39
Q4 24
$3.04
$-0.38
Q3 24
$3.49
$-0.12
Q2 24
$4.15
$-0.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXP
AXP
TLSI
TLSI
Cash + ST InvestmentsLiquidity on hand
$20.4M
Total DebtLower is stronger
$60.4M
Stockholders' EquityBook value
$34.0M
$-33.9M
Total Assets
$308.9M
$35.3M
Debt / EquityLower = less leverage
1.78×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
$742.0M
$20.4M
Q3 25
$1.3B
$22.7M
Q2 25
$197.0M
$26.5M
Q1 25
$261.0M
$13.0M
Q4 24
$221.0M
$8.5M
Q3 24
$120.0M
$11.3M
Q2 24
$188.0M
$16.5M
Total Debt
AXP
AXP
TLSI
TLSI
Q1 26
$60.4M
Q4 25
$56.4B
Q3 25
$57.8B
Q2 25
$58.2B
Q1 25
$51.2B
Q4 24
$49.7B
Q3 24
$53.5B
Q2 24
$51.5B
Stockholders' Equity
AXP
AXP
TLSI
TLSI
Q1 26
$34.0M
Q4 25
$33.5B
$-33.9M
Q3 25
$32.4B
$-26.7M
Q2 25
$32.3B
$-19.4M
Q1 25
$31.2B
$-34.4M
Q4 24
$30.3B
$-25.9M
Q3 24
$29.7B
$-20.4M
Q2 24
$29.5B
$-25.3M
Total Assets
AXP
AXP
TLSI
TLSI
Q1 26
$308.9M
Q4 25
$300.1B
$35.3M
Q3 25
$297.6B
$36.5M
Q2 25
$295.6B
$41.3M
Q1 25
$282.2B
$28.6M
Q4 24
$271.5B
$24.0M
Q3 24
$271.0B
$27.5M
Q2 24
$272.2B
$32.4M
Debt / Equity
AXP
AXP
TLSI
TLSI
Q1 26
1.78×
Q4 25
1.68×
Q3 25
1.78×
Q2 25
1.80×
Q1 25
1.64×
Q4 24
1.64×
Q3 24
1.80×
Q2 24
1.74×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXP
AXP
TLSI
TLSI
Operating Cash FlowLast quarter
$-2.5M
Free Cash FlowOCF − Capex
$-2.5M
FCF MarginFCF / Revenue
-19.1%
Capex IntensityCapex / Revenue
0.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-19.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
$3.1B
$-2.5M
Q3 25
$6.2B
$-3.7M
Q2 25
$4.4B
$-7.3M
Q1 25
$4.8B
$-4.5M
Q4 24
$5.8B
$-5.7M
Q3 24
$-1.8B
$-10.8M
Q2 24
$4.5B
$-13.4M
Free Cash Flow
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
$2.3B
$-2.5M
Q3 25
$5.6B
$-3.9M
Q2 25
$3.7B
$-7.4M
Q1 25
$4.3B
$-5.3M
Q4 24
$5.3B
$-5.8M
Q3 24
$-2.3B
$-11.0M
Q2 24
$4.0B
$-13.5M
FCF Margin
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
21.4%
-19.1%
Q3 25
53.6%
-33.9%
Q2 25
36.3%
-66.1%
Q1 25
45.0%
-57.3%
Q4 24
53.1%
-69.7%
Q3 24
-23.3%
-149.9%
Q2 24
40.4%
-183.1%
Capex Intensity
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
6.6%
0.3%
Q3 25
6.3%
1.9%
Q2 25
6.0%
0.8%
Q1 25
4.5%
8.2%
Q4 24
5.0%
0.6%
Q3 24
4.7%
2.3%
Q2 24
5.8%
0.8%
Cash Conversion
AXP
AXP
TLSI
TLSI
Q1 26
Q4 25
1.25×
Q3 25
2.15×
Q2 25
1.51×
Q1 25
1.84×
Q4 24
2.66×
Q3 24
-0.72×
Q2 24
1.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXP
AXP

Discount revenue$9.5M50%
Other$8.9M47%
Deposits with banks and other$512.0K3%

TLSI
TLSI

Segment breakdown not available.

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