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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and FIRST INTERSTATE BANCSYSTEM INC (FIBK). Click either name above to swap in a different company.
FIRST INTERSTATE BANCSYSTEM INC is the larger business by last-quarter revenue ($313.0M vs $196.0M, roughly 1.6× Axsome Therapeutics, Inc.). FIRST INTERSTATE BANCSYSTEM INC runs the higher net margin — 34.8% vs -14.6%, a 49.3% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs 19.8%). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 13.7%).
Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.
First Interstate BancSystem, Inc. is a financial holding company headquartered in Billings, Montana. It is the parent company of First Interstate Bank, a community bank with locations throughout 14 states within the Western and Midwestern United States. It is the largest bank based in Montana, as measured by total assets.
AXSM vs FIBK — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $196.0M | $313.0M |
| Net Profit | $-28.6M | $108.8M |
| Gross Margin | — | — |
| Operating Margin | -13.8% | 44.5% |
| Net Margin | -14.6% | 34.8% |
| Revenue YoY | 65.0% | 19.8% |
| Net Profit YoY | 61.9% | 108.8% |
| EPS (diluted) | $-0.55 | $1.07 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $196.0M | $313.0M | ||
| Q3 25 | $171.0M | $250.5M | ||
| Q2 25 | $150.0M | $248.3M | ||
| Q1 25 | $121.5M | $247.0M | ||
| Q4 24 | $118.8M | $261.3M | ||
| Q3 24 | $104.8M | $251.9M | ||
| Q2 24 | $87.2M | $244.3M | ||
| Q1 24 | $75.0M | $242.2M |
| Q4 25 | $-28.6M | $108.8M | ||
| Q3 25 | $-47.2M | $71.4M | ||
| Q2 25 | $-48.0M | $71.7M | ||
| Q1 25 | $-59.4M | $50.2M | ||
| Q4 24 | $-74.9M | $52.1M | ||
| Q3 24 | $-64.6M | $55.5M | ||
| Q2 24 | $-79.3M | $60.0M | ||
| Q1 24 | $-68.4M | $58.4M |
| Q4 25 | -13.8% | 44.5% | ||
| Q3 25 | -27.0% | 37.0% | ||
| Q2 25 | -24.5% | 37.7% | ||
| Q1 25 | -46.9% | 26.9% | ||
| Q4 24 | -61.1% | 25.5% | ||
| Q3 24 | -59.8% | 28.9% | ||
| Q2 24 | -89.5% | 32.1% | ||
| Q1 24 | -89.7% | 31.7% |
| Q4 25 | -14.6% | 34.8% | ||
| Q3 25 | -27.6% | 28.5% | ||
| Q2 25 | -32.0% | 28.9% | ||
| Q1 25 | -48.9% | 20.3% | ||
| Q4 24 | -63.1% | 19.9% | ||
| Q3 24 | -61.7% | 22.0% | ||
| Q2 24 | -91.0% | 24.6% | ||
| Q1 24 | -91.1% | 24.1% |
| Q4 25 | $-0.55 | $1.07 | ||
| Q3 25 | $-0.94 | $0.69 | ||
| Q2 25 | $-0.97 | $0.69 | ||
| Q1 25 | $-1.22 | $0.49 | ||
| Q4 24 | $-1.54 | $0.50 | ||
| Q3 24 | $-1.34 | $0.54 | ||
| Q2 24 | $-1.67 | $0.58 | ||
| Q1 24 | $-1.44 | $0.57 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $322.9M | — |
| Total DebtLower is stronger | — | $146.3M |
| Stockholders' EquityBook value | $88.3M | $3.4B |
| Total Assets | $689.8M | $26.6B |
| Debt / EquityLower = less leverage | — | 0.04× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $322.9M | — | ||
| Q3 25 | $325.3M | — | ||
| Q2 25 | $303.0M | — | ||
| Q1 25 | $300.9M | — | ||
| Q4 24 | $315.4M | — | ||
| Q3 24 | $327.3M | — | ||
| Q2 24 | $315.7M | — | ||
| Q1 24 | $331.4M | — |
| Q4 25 | — | $146.3M | ||
| Q3 25 | — | $146.2M | ||
| Q2 25 | — | $252.0M | ||
| Q1 25 | — | — | ||
| Q4 24 | — | $132.2M | ||
| Q3 24 | — | $137.3M | ||
| Q2 24 | — | $383.4M | ||
| Q1 24 | — | $370.8M |
| Q4 25 | $88.3M | $3.4B | ||
| Q3 25 | $73.7M | $3.4B | ||
| Q2 25 | $73.1M | $3.4B | ||
| Q1 25 | $53.2M | $3.4B | ||
| Q4 24 | $57.0M | $3.3B | ||
| Q3 24 | $92.9M | $3.4B | ||
| Q2 24 | $102.9M | $3.2B | ||
| Q1 24 | $144.0M | $3.2B |
| Q4 25 | $689.8M | $26.6B | ||
| Q3 25 | $669.3M | $27.3B | ||
| Q2 25 | $639.8M | $27.6B | ||
| Q1 25 | $596.7M | $28.3B | ||
| Q4 24 | $568.5M | $29.1B | ||
| Q3 24 | $561.5M | $29.6B | ||
| Q2 24 | $548.2M | $30.3B | ||
| Q1 24 | $545.7M | $30.1B |
| Q4 25 | — | 0.04× | ||
| Q3 25 | — | 0.04× | ||
| Q2 25 | — | 0.07× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.04× | ||
| Q3 24 | — | 0.04× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 0.12× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-18.7M | $305.6M |
| Free Cash FlowOCF − Capex | $-18.7M | — |
| FCF MarginFCF / Revenue | -9.6% | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | — | 2.81× |
| TTM Free Cash FlowTrailing 4 quarters | $-93.9M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-18.7M | $305.6M | ||
| Q3 25 | $1.0M | $91.7M | ||
| Q2 25 | $-32.4M | $68.1M | ||
| Q1 25 | $-43.4M | $78.5M | ||
| Q4 24 | $-26.2M | $355.0M | ||
| Q3 24 | $-18.6M | $89.9M | ||
| Q2 24 | $-30.1M | $82.3M | ||
| Q1 24 | $-53.5M | $87.6M |
| Q4 25 | $-18.7M | — | ||
| Q3 25 | $988.0K | — | ||
| Q2 25 | $-32.4M | — | ||
| Q1 25 | $-43.7M | — | ||
| Q4 24 | $-26.2M | — | ||
| Q3 24 | $-18.7M | — | ||
| Q2 24 | $-30.2M | — | ||
| Q1 24 | $-53.6M | — |
| Q4 25 | -9.6% | — | ||
| Q3 25 | 0.6% | — | ||
| Q2 25 | -21.6% | — | ||
| Q1 25 | -36.0% | — | ||
| Q4 24 | -22.1% | — | ||
| Q3 24 | -17.9% | — | ||
| Q2 24 | -34.6% | — | ||
| Q1 24 | -71.4% | — |
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.0% | — | ||
| Q1 25 | 0.3% | — | ||
| Q4 24 | 0.0% | — | ||
| Q3 24 | 0.1% | — | ||
| Q2 24 | 0.1% | — | ||
| Q1 24 | 0.1% | — |
| Q4 25 | — | 2.81× | ||
| Q3 25 | — | 1.28× | ||
| Q2 25 | — | 0.95× | ||
| Q1 25 | — | 1.56× | ||
| Q4 24 | — | 6.81× | ||
| Q3 24 | — | 1.62× | ||
| Q2 24 | — | 1.37× | ||
| Q1 24 | — | 1.50× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
