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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and Grand Canyon Education, Inc. (LOPE). Click either name above to swap in a different company.

Grand Canyon Education, Inc. is the larger business by last-quarter revenue ($308.1M vs $196.0M, roughly 1.6× Axsome Therapeutics, Inc.). Grand Canyon Education, Inc. runs the higher net margin — 28.1% vs -14.6%, a 42.7% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs 5.3%). Grand Canyon Education, Inc. produced more free cash flow last quarter ($122.9M vs $-18.7M). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 5.9%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Grand Canyon Education, Inc. (GCE) is an American for-profit corporation that provides services to universities, specializing in program development, online education, and operational support. Formerly affiliated with Grand Canyon University (GCU), a Christian university in Arizona, GCE became a separate publicly traded company in 2008.

AXSM vs LOPE — Head-to-Head

Bigger by revenue
LOPE
LOPE
1.6× larger
LOPE
$308.1M
$196.0M
AXSM
Growing faster (revenue YoY)
AXSM
AXSM
+59.7% gap
AXSM
65.0%
5.3%
LOPE
Higher net margin
LOPE
LOPE
42.7% more per $
LOPE
28.1%
-14.6%
AXSM
More free cash flow
LOPE
LOPE
$141.6M more FCF
LOPE
$122.9M
$-18.7M
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
61.7%
5.9%
LOPE

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AXSM
AXSM
LOPE
LOPE
Revenue
$196.0M
$308.1M
Net Profit
$-28.6M
$86.7M
Gross Margin
Operating Margin
-13.8%
35.1%
Net Margin
-14.6%
28.1%
Revenue YoY
65.0%
5.3%
Net Profit YoY
61.9%
5.9%
EPS (diluted)
$-0.55
$3.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
LOPE
LOPE
Q4 25
$196.0M
$308.1M
Q3 25
$171.0M
$261.1M
Q2 25
$150.0M
$247.5M
Q1 25
$121.5M
$289.3M
Q4 24
$118.8M
$292.6M
Q3 24
$104.8M
$238.3M
Q2 24
$87.2M
$227.5M
Q1 24
$75.0M
$274.7M
Net Profit
AXSM
AXSM
LOPE
LOPE
Q4 25
$-28.6M
$86.7M
Q3 25
$-47.2M
$16.3M
Q2 25
$-48.0M
$41.5M
Q1 25
$-59.4M
$71.6M
Q4 24
$-74.9M
$81.9M
Q3 24
$-64.6M
$41.5M
Q2 24
$-79.3M
$34.9M
Q1 24
$-68.4M
$68.0M
Operating Margin
AXSM
AXSM
LOPE
LOPE
Q4 25
-13.8%
35.1%
Q3 25
-27.0%
6.9%
Q2 25
-24.5%
20.9%
Q1 25
-46.9%
30.4%
Q4 24
-61.1%
34.2%
Q3 24
-59.8%
20.2%
Q2 24
-89.5%
18.8%
Q1 24
-89.7%
30.8%
Net Margin
AXSM
AXSM
LOPE
LOPE
Q4 25
-14.6%
28.1%
Q3 25
-27.6%
6.2%
Q2 25
-32.0%
16.8%
Q1 25
-48.9%
24.8%
Q4 24
-63.1%
28.0%
Q3 24
-61.7%
17.4%
Q2 24
-91.0%
15.3%
Q1 24
-91.1%
24.8%
EPS (diluted)
AXSM
AXSM
LOPE
LOPE
Q4 25
$-0.55
$3.13
Q3 25
$-0.94
$0.58
Q2 25
$-0.97
$1.48
Q1 25
$-1.22
$2.52
Q4 24
$-1.54
$2.83
Q3 24
$-1.34
$1.42
Q2 24
$-1.67
$1.19
Q1 24
$-1.44
$2.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
LOPE
LOPE
Cash + ST InvestmentsLiquidity on hand
$322.9M
$111.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$88.3M
$746.9M
Total Assets
$689.8M
$992.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
LOPE
LOPE
Q4 25
$322.9M
$111.8M
Q3 25
$325.3M
$97.3M
Q2 25
$303.0M
$192.3M
Q1 25
$300.9M
$144.5M
Q4 24
$315.4M
$324.6M
Q3 24
$327.3M
$263.6M
Q2 24
$315.7M
$241.3M
Q1 24
$331.4M
$196.2M
Stockholders' Equity
AXSM
AXSM
LOPE
LOPE
Q4 25
$88.3M
$746.9M
Q3 25
$73.7M
$758.0M
Q2 25
$73.1M
$778.0M
Q1 25
$53.2M
$780.7M
Q4 24
$57.0M
$783.9M
Q3 24
$92.9M
$764.1M
Q2 24
$102.9M
$759.2M
Q1 24
$144.0M
$759.4M
Total Assets
AXSM
AXSM
LOPE
LOPE
Q4 25
$689.8M
$992.3M
Q3 25
$669.3M
$1.0B
Q2 25
$639.8M
$1.0B
Q1 25
$596.7M
$1.0B
Q4 24
$568.5M
$1.0B
Q3 24
$561.5M
$992.9M
Q2 24
$548.2M
$992.7M
Q1 24
$545.7M
$1.0B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
LOPE
LOPE
Operating Cash FlowLast quarter
$-18.7M
$130.5M
Free Cash FlowOCF − Capex
$-18.7M
$122.9M
FCF MarginFCF / Revenue
-9.6%
39.9%
Capex IntensityCapex / Revenue
0.0%
2.5%
Cash ConversionOCF / Net Profit
1.50×
TTM Free Cash FlowTrailing 4 quarters
$-93.9M
$238.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
LOPE
LOPE
Q4 25
$-18.7M
$130.5M
Q3 25
$1.0M
$-48.6M
Q2 25
$-32.4M
$124.0M
Q1 25
$-43.4M
$67.6M
Q4 24
$-26.2M
$135.8M
Q3 24
$-18.6M
$-29.4M
Q2 24
$-30.1M
$98.6M
Q1 24
$-53.5M
$85.0M
Free Cash Flow
AXSM
AXSM
LOPE
LOPE
Q4 25
$-18.7M
$122.9M
Q3 25
$988.0K
$-58.3M
Q2 25
$-32.4M
$115.4M
Q1 25
$-43.7M
$58.7M
Q4 24
$-26.2M
$126.1M
Q3 24
$-18.7M
$-39.0M
Q2 24
$-30.2M
$89.6M
Q1 24
$-53.6M
$76.0M
FCF Margin
AXSM
AXSM
LOPE
LOPE
Q4 25
-9.6%
39.9%
Q3 25
0.6%
-22.3%
Q2 25
-21.6%
46.6%
Q1 25
-36.0%
20.3%
Q4 24
-22.1%
43.1%
Q3 24
-17.9%
-16.3%
Q2 24
-34.6%
39.4%
Q1 24
-71.4%
27.7%
Capex Intensity
AXSM
AXSM
LOPE
LOPE
Q4 25
0.0%
2.5%
Q3 25
0.0%
3.7%
Q2 25
0.0%
3.5%
Q1 25
0.3%
3.1%
Q4 24
0.0%
3.3%
Q3 24
0.1%
4.0%
Q2 24
0.1%
3.9%
Q1 24
0.1%
3.3%
Cash Conversion
AXSM
AXSM
LOPE
LOPE
Q4 25
1.50×
Q3 25
-2.99×
Q2 25
2.98×
Q1 25
0.94×
Q4 24
1.66×
Q3 24
-0.71×
Q2 24
2.83×
Q1 24
1.25×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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