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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and National Bank Holdings Corp (NBHC). Click either name above to swap in a different company.

Axsome Therapeutics, Inc. is the larger business by last-quarter revenue ($191.2M vs $126.8M, roughly 1.5× National Bank Holdings Corp). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (48.1% CAGR vs 14.0%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Old National Bank is an American regional bank with nearly 200 retail branches operated by Old National Bancorp and based in Chicago and Evansville, Indiana. With assets at $48.5 billion and 250 banking centers, Old National Bancorp is the largest financial services bank holding company headquartered in Indiana and one of the top 30 banking companies in the U.S. Old National Bank has locations in Illinois, Indiana, Iowa, Kentucky, Michigan, Minnesota, Tennessee, and Wisconsin.

AXSM vs NBHC — Head-to-Head

Bigger by revenue
AXSM
AXSM
1.5× larger
AXSM
$191.2M
$126.8M
NBHC
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
48.1%
14.0%
NBHC

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
AXSM
AXSM
NBHC
NBHC
Revenue
$191.2M
$126.8M
Net Profit
$20.8M
Gross Margin
Operating Margin
-33.1%
Net Margin
16.4%
Revenue YoY
57.4%
Net Profit YoY
-14.2%
EPS (diluted)
$0.46

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
NBHC
NBHC
Q1 26
$191.2M
$126.8M
Q4 25
$196.0M
$100.6M
Q3 25
$171.0M
$108.9M
Q2 25
$150.0M
$104.5M
Q1 25
$121.5M
$102.1M
Q4 24
$118.8M
$101.3M
Q3 24
$104.8M
$106.0M
Q2 24
$87.2M
$97.6M
Net Profit
AXSM
AXSM
NBHC
NBHC
Q1 26
$20.8M
Q4 25
$-28.6M
$16.0M
Q3 25
$-47.2M
$35.3M
Q2 25
$-48.0M
$34.0M
Q1 25
$-59.4M
$24.2M
Q4 24
$-74.9M
$28.2M
Q3 24
$-64.6M
$33.1M
Q2 24
$-79.3M
$26.1M
Operating Margin
AXSM
AXSM
NBHC
NBHC
Q1 26
-33.1%
Q4 25
-13.8%
19.0%
Q3 25
-27.0%
39.6%
Q2 25
-24.5%
39.8%
Q1 25
-46.9%
29.2%
Q4 24
-61.1%
34.3%
Q3 24
-59.8%
37.6%
Q2 24
-89.5%
32.5%
Net Margin
AXSM
AXSM
NBHC
NBHC
Q1 26
16.4%
Q4 25
-14.6%
15.9%
Q3 25
-27.6%
32.4%
Q2 25
-32.0%
32.6%
Q1 25
-48.9%
23.7%
Q4 24
-63.1%
27.8%
Q3 24
-61.7%
31.2%
Q2 24
-91.0%
26.8%
EPS (diluted)
AXSM
AXSM
NBHC
NBHC
Q1 26
$0.46
Q4 25
$-0.55
$0.42
Q3 25
$-0.94
$0.92
Q2 25
$-0.97
$0.88
Q1 25
$-1.22
$0.63
Q4 24
$-1.54
$0.72
Q3 24
$-1.34
$0.86
Q2 24
$-1.67
$0.68

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
NBHC
NBHC
Cash + ST InvestmentsLiquidity on hand
$305.1M
$472.8M
Total DebtLower is stronger
$70.0M
$202.1M
Stockholders' EquityBook value
$1.7B
Total Assets
$713.6M
$12.6B
Debt / EquityLower = less leverage
0.12×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
NBHC
NBHC
Q1 26
$305.1M
$472.8M
Q4 25
$322.9M
$417.1M
Q3 25
$325.3M
$555.6M
Q2 25
$303.0M
$296.5M
Q1 25
$300.9M
$246.3M
Q4 24
$315.4M
$127.8M
Q3 24
$327.3M
$180.8M
Q2 24
$315.7M
$145.0M
Total Debt
AXSM
AXSM
NBHC
NBHC
Q1 26
$70.0M
$202.1M
Q4 25
$54.5M
Q3 25
$54.7M
Q2 25
$54.4M
Q1 25
$54.6M
Q4 24
$54.5M
Q3 24
$54.4M
Q2 24
$54.4M
Stockholders' Equity
AXSM
AXSM
NBHC
NBHC
Q1 26
$1.7B
Q4 25
$88.3M
$1.4B
Q3 25
$73.7M
$1.4B
Q2 25
$73.1M
$1.4B
Q1 25
$53.2M
$1.3B
Q4 24
$57.0M
$1.3B
Q3 24
$92.9M
$1.3B
Q2 24
$102.9M
$1.2B
Total Assets
AXSM
AXSM
NBHC
NBHC
Q1 26
$713.6M
$12.6B
Q4 25
$689.8M
$9.9B
Q3 25
$669.3M
$10.2B
Q2 25
$639.8M
$10.0B
Q1 25
$596.7M
$10.1B
Q4 24
$568.5M
$9.8B
Q3 24
$561.5M
$10.0B
Q2 24
$548.2M
$10.0B
Debt / Equity
AXSM
AXSM
NBHC
NBHC
Q1 26
0.12×
Q4 25
0.04×
Q3 25
0.04×
Q2 25
0.04×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.04×
Q2 24
0.04×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Product sales, net$189.4M99%
Royalty revenue and milestone revenue$1.8M1%

NBHC
NBHC

Net Interest Income$108.8M86%
Noninterest Income$18.0M14%

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