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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and NU SKIN ENTERPRISES, INC. (NUS). Click either name above to swap in a different company.

NU SKIN ENTERPRISES, INC. is the larger business by last-quarter revenue ($370.3M vs $196.0M, roughly 1.9× Axsome Therapeutics, Inc.). NU SKIN ENTERPRISES, INC. runs the higher net margin — 3.9% vs -14.6%, a 18.5% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs -16.9%). NU SKIN ENTERPRISES, INC. produced more free cash flow last quarter ($5.9M vs $-18.7M). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs -5.8%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Nu Skin Enterprises, Inc. is an American multilevel marketing company that develops and sells personal care products and dietary and nutritional supplements. Under the Nu Skin and Pharmanex brands, the company sells its products in 54 markets through a network of approximately 1.2 million independent distributors.

AXSM vs NUS — Head-to-Head

Bigger by revenue
NUS
NUS
1.9× larger
NUS
$370.3M
$196.0M
AXSM
Growing faster (revenue YoY)
AXSM
AXSM
+81.9% gap
AXSM
65.0%
-16.9%
NUS
Higher net margin
NUS
NUS
18.5% more per $
NUS
3.9%
-14.6%
AXSM
More free cash flow
NUS
NUS
$24.6M more FCF
NUS
$5.9M
$-18.7M
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
61.7%
-5.8%
NUS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AXSM
AXSM
NUS
NUS
Revenue
$196.0M
$370.3M
Net Profit
$-28.6M
$14.5M
Gross Margin
70.7%
Operating Margin
-13.8%
6.3%
Net Margin
-14.6%
3.9%
Revenue YoY
65.0%
-16.9%
Net Profit YoY
61.9%
140.1%
EPS (diluted)
$-0.55
$0.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
NUS
NUS
Q4 25
$196.0M
$370.3M
Q3 25
$171.0M
$364.2M
Q2 25
$150.0M
$386.1M
Q1 25
$121.5M
$364.5M
Q4 24
$118.8M
$445.6M
Q3 24
$104.8M
$430.1M
Q2 24
$87.2M
$439.1M
Q1 24
$75.0M
$417.3M
Net Profit
AXSM
AXSM
NUS
NUS
Q4 25
$-28.6M
$14.5M
Q3 25
$-47.2M
$17.1M
Q2 25
$-48.0M
$21.1M
Q1 25
$-59.4M
$107.5M
Q4 24
$-74.9M
$-36.1M
Q3 24
$-64.6M
$8.3M
Q2 24
$-79.3M
$-118.3M
Q1 24
$-68.4M
$-533.0K
Gross Margin
AXSM
AXSM
NUS
NUS
Q4 25
70.7%
Q3 25
70.5%
Q2 25
68.8%
Q1 25
67.8%
Q4 24
62.7%
Q3 24
70.1%
Q2 24
70.0%
Q1 24
70.5%
Operating Margin
AXSM
AXSM
NUS
NUS
Q4 25
-13.8%
6.3%
Q3 25
-27.0%
5.9%
Q2 25
-24.5%
8.0%
Q1 25
-46.9%
-2.7%
Q4 24
-61.1%
-11.9%
Q3 24
-59.8%
4.2%
Q2 24
-89.5%
-28.6%
Q1 24
-89.7%
2.1%
Net Margin
AXSM
AXSM
NUS
NUS
Q4 25
-14.6%
3.9%
Q3 25
-27.6%
4.7%
Q2 25
-32.0%
5.5%
Q1 25
-48.9%
29.5%
Q4 24
-63.1%
-8.1%
Q3 24
-61.7%
1.9%
Q2 24
-91.0%
-26.9%
Q1 24
-91.1%
-0.1%
EPS (diluted)
AXSM
AXSM
NUS
NUS
Q4 25
$-0.55
$0.27
Q3 25
$-0.94
$0.34
Q2 25
$-0.97
$0.43
Q1 25
$-1.22
$2.14
Q4 24
$-1.54
$-0.73
Q3 24
$-1.34
$0.17
Q2 24
$-1.67
$-2.38
Q1 24
$-1.44
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
NUS
NUS
Cash + ST InvestmentsLiquidity on hand
$322.9M
$239.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$88.3M
$805.2M
Total Assets
$689.8M
$1.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
NUS
NUS
Q4 25
$322.9M
$239.8M
Q3 25
$325.3M
$253.0M
Q2 25
$303.0M
$265.4M
Q1 25
$300.9M
$213.6M
Q4 24
$315.4M
$198.0M
Q3 24
$327.3M
$237.8M
Q2 24
$315.7M
$232.9M
Q1 24
$331.4M
$221.2M
Stockholders' Equity
AXSM
AXSM
NUS
NUS
Q4 25
$88.3M
$805.2M
Q3 25
$73.7M
$799.8M
Q2 25
$73.1M
$787.8M
Q1 25
$53.2M
$754.0M
Q4 24
$57.0M
$651.5M
Q3 24
$92.9M
$706.9M
Q2 24
$102.9M
$686.2M
Q1 24
$144.0M
$810.2M
Total Assets
AXSM
AXSM
NUS
NUS
Q4 25
$689.8M
$1.4B
Q3 25
$669.3M
$1.4B
Q2 25
$639.8M
$1.4B
Q1 25
$596.7M
$1.4B
Q4 24
$568.5M
$1.5B
Q3 24
$561.5M
$1.6B
Q2 24
$548.2M
$1.6B
Q1 24
$545.7M
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
NUS
NUS
Operating Cash FlowLast quarter
$-18.7M
$16.6M
Free Cash FlowOCF − Capex
$-18.7M
$5.9M
FCF MarginFCF / Revenue
-9.6%
1.6%
Capex IntensityCapex / Revenue
0.0%
2.9%
Cash ConversionOCF / Net Profit
1.15×
TTM Free Cash FlowTrailing 4 quarters
$-93.9M
$46.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
NUS
NUS
Q4 25
$-18.7M
$16.6M
Q3 25
$1.0M
$27.5M
Q2 25
$-32.4M
$35.8M
Q1 25
$-43.4M
$389.0K
Q4 24
$-26.2M
$25.8M
Q3 24
$-18.6M
$31.4M
Q2 24
$-30.1M
$51.2M
Q1 24
$-53.5M
$3.3M
Free Cash Flow
AXSM
AXSM
NUS
NUS
Q4 25
$-18.7M
$5.9M
Q3 25
$988.0K
$17.6M
Q2 25
$-32.4M
$35.8M
Q1 25
$-43.7M
$-13.2M
Q4 24
$-26.2M
$13.2M
Q3 24
$-18.7M
$22.8M
Q2 24
$-30.2M
$43.1M
Q1 24
$-53.6M
$-9.0M
FCF Margin
AXSM
AXSM
NUS
NUS
Q4 25
-9.6%
1.6%
Q3 25
0.6%
4.8%
Q2 25
-21.6%
9.3%
Q1 25
-36.0%
-3.6%
Q4 24
-22.1%
3.0%
Q3 24
-17.9%
5.3%
Q2 24
-34.6%
9.8%
Q1 24
-71.4%
-2.1%
Capex Intensity
AXSM
AXSM
NUS
NUS
Q4 25
0.0%
2.9%
Q3 25
0.0%
2.7%
Q2 25
0.0%
0.0%
Q1 25
0.3%
3.7%
Q4 24
0.0%
2.8%
Q3 24
0.1%
2.0%
Q2 24
0.1%
1.9%
Q1 24
0.1%
2.9%
Cash Conversion
AXSM
AXSM
NUS
NUS
Q4 25
1.15×
Q3 25
1.61×
Q2 25
1.69×
Q1 25
0.00×
Q4 24
Q3 24
3.79×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Segment breakdown not available.

NUS
NUS

Other$161.9M44%
Mainland China Segment$52.0M14%
Southeast Asia Pacific Segment$50.5M14%
Europe And Africa Segment$41.8M11%
Hong Kong Taiwan Segment$29.6M8%
South Korea Segment$28.4M8%
Rhyz Other Segment$6.1M2%

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