vs

Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.

PROSPERITY BANCSHARES INC is the larger business by last-quarter revenue ($367.6M vs $196.0M, roughly 1.9× Axsome Therapeutics, Inc.). PROSPERITY BANCSHARES INC runs the higher net margin — 31.6% vs -14.6%, a 46.2% gap on every dollar of revenue. Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 19.2%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...

AXSM vs PB — Head-to-Head

Bigger by revenue
PB
PB
1.9× larger
PB
$367.6M
$196.0M
AXSM
Higher net margin
PB
PB
46.2% more per $
PB
31.6%
-14.6%
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
61.7%
19.2%
PB

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
AXSM
AXSM
PB
PB
Revenue
$196.0M
$367.6M
Net Profit
$-28.6M
$116.3M
Gross Margin
Operating Margin
-13.8%
Net Margin
-14.6%
31.6%
Revenue YoY
65.0%
Net Profit YoY
61.9%
-10.7%
EPS (diluted)
$-0.55
$1.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
PB
PB
Q1 26
$367.6M
Q4 25
$196.0M
$275.0M
Q3 25
$171.0M
$273.4M
Q2 25
$150.0M
$267.7M
Q1 25
$121.5M
$265.4M
Q4 24
$118.8M
$267.8M
Q3 24
$104.8M
$261.7M
Q2 24
$87.2M
$258.8M
Net Profit
AXSM
AXSM
PB
PB
Q1 26
$116.3M
Q4 25
$-28.6M
$139.9M
Q3 25
$-47.2M
$137.6M
Q2 25
$-48.0M
$135.2M
Q1 25
$-59.4M
$130.2M
Q4 24
$-74.9M
$130.1M
Q3 24
$-64.6M
$127.3M
Q2 24
$-79.3M
$111.6M
Operating Margin
AXSM
AXSM
PB
PB
Q1 26
Q4 25
-13.8%
65.1%
Q3 25
-27.0%
64.4%
Q2 25
-24.5%
64.3%
Q1 25
-46.9%
62.7%
Q4 24
-61.1%
62.0%
Q3 24
-59.8%
62.1%
Q2 24
-89.5%
55.2%
Net Margin
AXSM
AXSM
PB
PB
Q1 26
31.6%
Q4 25
-14.6%
50.9%
Q3 25
-27.6%
50.3%
Q2 25
-32.0%
50.5%
Q1 25
-48.9%
49.1%
Q4 24
-63.1%
48.6%
Q3 24
-61.7%
48.6%
Q2 24
-91.0%
43.1%
EPS (diluted)
AXSM
AXSM
PB
PB
Q1 26
$1.16
Q4 25
$-0.55
$1.48
Q3 25
$-0.94
$1.45
Q2 25
$-0.97
$1.42
Q1 25
$-1.22
$1.37
Q4 24
$-1.54
$1.36
Q3 24
$-1.34
$1.34
Q2 24
$-1.67
$1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
PB
PB
Cash + ST InvestmentsLiquidity on hand
$322.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$88.3M
$8.2B
Total Assets
$689.8M
$43.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
PB
PB
Q1 26
Q4 25
$322.9M
Q3 25
$325.3M
Q2 25
$303.0M
Q1 25
$300.9M
Q4 24
$315.4M
Q3 24
$327.3M
Q2 24
$315.7M
Stockholders' Equity
AXSM
AXSM
PB
PB
Q1 26
$8.2B
Q4 25
$88.3M
$7.6B
Q3 25
$73.7M
$7.7B
Q2 25
$73.1M
$7.6B
Q1 25
$53.2M
$7.5B
Q4 24
$57.0M
$7.4B
Q3 24
$92.9M
$7.4B
Q2 24
$102.9M
$7.3B
Total Assets
AXSM
AXSM
PB
PB
Q1 26
$43.6B
Q4 25
$689.8M
$38.5B
Q3 25
$669.3M
$38.3B
Q2 25
$639.8M
$38.4B
Q1 25
$596.7M
$38.8B
Q4 24
$568.5M
$39.6B
Q3 24
$561.5M
$40.1B
Q2 24
$548.2M
$39.8B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
PB
PB
Operating Cash FlowLast quarter
$-18.7M
Free Cash FlowOCF − Capex
$-18.7M
FCF MarginFCF / Revenue
-9.6%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
PB
PB
Q1 26
Q4 25
$-18.7M
$78.3M
Q3 25
$1.0M
$194.8M
Q2 25
$-32.4M
$98.2M
Q1 25
$-43.4M
$178.2M
Q4 24
$-26.2M
$-205.8M
Q3 24
$-18.6M
$274.6M
Q2 24
$-30.1M
$216.5M
Free Cash Flow
AXSM
AXSM
PB
PB
Q1 26
Q4 25
$-18.7M
$68.5M
Q3 25
$988.0K
$185.7M
Q2 25
$-32.4M
$91.8M
Q1 25
$-43.7M
$171.1M
Q4 24
$-26.2M
$-210.7M
Q3 24
$-18.7M
$270.2M
Q2 24
$-30.2M
$211.8M
FCF Margin
AXSM
AXSM
PB
PB
Q1 26
Q4 25
-9.6%
24.9%
Q3 25
0.6%
67.9%
Q2 25
-21.6%
34.3%
Q1 25
-36.0%
64.5%
Q4 24
-22.1%
-78.7%
Q3 24
-17.9%
103.3%
Q2 24
-34.6%
81.8%
Capex Intensity
AXSM
AXSM
PB
PB
Q1 26
Q4 25
0.0%
3.6%
Q3 25
0.0%
3.3%
Q2 25
0.0%
2.4%
Q1 25
0.3%
2.7%
Q4 24
0.0%
1.8%
Q3 24
0.1%
1.7%
Q2 24
0.1%
1.8%
Cash Conversion
AXSM
AXSM
PB
PB
Q1 26
Q4 25
0.56×
Q3 25
1.42×
Q2 25
0.73×
Q1 25
1.37×
Q4 24
-1.58×
Q3 24
2.16×
Q2 24
1.94×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Segment breakdown not available.

PB
PB

Net Interest Income$321.1M87%
Noninterest Income$46.5M13%

Related Comparisons