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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and TRUPANION, INC. (TRUP). Click either name above to swap in a different company.

TRUPANION, INC. is the larger business by last-quarter revenue ($376.9M vs $191.2M, roughly 2.0× Axsome Therapeutics, Inc.). On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (57.4% vs 11.7%). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (48.1% CAGR vs 11.0%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Trupanion, Inc. is a pet insurance provider headquartered in Seattle, Washington. Established in 1998, Trupanion operates across the United States, Canada, Australia, and Puerto Rico. The company offers coverage for pets and is self-underwritten by the American Pet Insurance Company (APIC).

AXSM vs TRUP — Head-to-Head

Bigger by revenue
TRUP
TRUP
2.0× larger
TRUP
$376.9M
$191.2M
AXSM
Growing faster (revenue YoY)
AXSM
AXSM
+45.7% gap
AXSM
57.4%
11.7%
TRUP
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
48.1%
11.0%
TRUP

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
AXSM
AXSM
TRUP
TRUP
Revenue
$191.2M
$376.9M
Net Profit
Gross Margin
17.3%
Operating Margin
-33.1%
1.9%
Net Margin
Revenue YoY
57.4%
11.7%
Net Profit YoY
EPS (diluted)
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
TRUP
TRUP
Q1 26
$191.2M
Q4 25
$196.0M
$376.9M
Q3 25
$171.0M
$366.9M
Q2 25
$150.0M
$353.6M
Q1 25
$121.5M
$342.0M
Q4 24
$118.8M
$337.3M
Q3 24
$104.8M
$327.5M
Q2 24
$87.2M
$314.8M
Net Profit
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
$-28.6M
Q3 25
$-47.2M
Q2 25
$-48.0M
Q1 25
$-59.4M
Q4 24
$-74.9M
Q3 24
$-64.6M
Q2 24
$-79.3M
Gross Margin
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
17.3%
Q3 25
16.4%
Q2 25
15.5%
Q1 25
14.9%
Q4 24
15.7%
Q3 24
15.1%
Q2 24
12.8%
Operating Margin
AXSM
AXSM
TRUP
TRUP
Q1 26
-33.1%
Q4 25
-13.8%
1.9%
Q3 25
-27.0%
1.6%
Q2 25
-24.5%
0.7%
Q1 25
-46.9%
-0.4%
Q4 24
-61.1%
0.1%
Q3 24
-59.8%
0.5%
Q2 24
-89.5%
-1.7%
Net Margin
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
-14.6%
Q3 25
-27.6%
Q2 25
-32.0%
Q1 25
-48.9%
Q4 24
-63.1%
Q3 24
-61.7%
Q2 24
-91.0%
EPS (diluted)
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
$-0.55
$0.13
Q3 25
$-0.94
$0.13
Q2 25
$-0.97
$0.22
Q1 25
$-1.22
$-0.03
Q4 24
$-1.54
$0.04
Q3 24
$-1.34
$0.03
Q2 24
$-1.67
$-0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
TRUP
TRUP
Cash + ST InvestmentsLiquidity on hand
$305.1M
$370.7M
Total DebtLower is stronger
$70.0M
$101.8M
Stockholders' EquityBook value
$383.9M
Total Assets
$713.6M
$915.0M
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
TRUP
TRUP
Q1 26
$305.1M
Q4 25
$322.9M
$370.7M
Q3 25
$325.3M
$348.5M
Q2 25
$303.0M
$319.6M
Q1 25
$300.9M
$321.8M
Q4 24
$315.4M
$307.4M
Q3 24
$327.3M
$293.1M
Q2 24
$315.7M
$277.2M
Total Debt
AXSM
AXSM
TRUP
TRUP
Q1 26
$70.0M
Q4 25
$101.8M
Q3 25
Q2 25
Q1 25
Q4 24
$127.5M
Q3 24
Q2 24
Stockholders' Equity
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
$88.3M
$383.9M
Q3 25
$73.7M
$368.6M
Q2 25
$73.1M
$355.5M
Q1 25
$53.2M
$333.7M
Q4 24
$57.0M
$323.3M
Q3 24
$92.9M
$320.2M
Q2 24
$102.9M
$305.8M
Total Assets
AXSM
AXSM
TRUP
TRUP
Q1 26
$713.6M
Q4 25
$689.8M
$915.0M
Q3 25
$669.3M
$880.2M
Q2 25
$639.8M
$847.8M
Q1 25
$596.7M
$837.2M
Q4 24
$568.5M
$806.9M
Q3 24
$561.5M
$816.1M
Q2 24
$548.2M
$795.9M
Debt / Equity
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
0.27×
Q3 25
Q2 25
Q1 25
Q4 24
0.39×
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
TRUP
TRUP
Operating Cash FlowLast quarter
$29.3M
Free Cash FlowOCF − Capex
$25.3M
FCF MarginFCF / Revenue
6.7%
Capex IntensityCapex / Revenue
1.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$75.4M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
$-18.7M
$29.3M
Q3 25
$1.0M
$29.2M
Q2 25
$-32.4M
$15.0M
Q1 25
$-43.4M
$16.0M
Q4 24
$-26.2M
$23.7M
Q3 24
$-18.6M
$15.3M
Q2 24
$-30.1M
$6.9M
Free Cash Flow
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
$-18.7M
$25.3M
Q3 25
$988.0K
$23.9M
Q2 25
$-32.4M
$12.0M
Q1 25
$-43.7M
$14.0M
Q4 24
$-26.2M
$21.8M
Q3 24
$-18.7M
$13.4M
Q2 24
$-30.2M
$4.0M
FCF Margin
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
-9.6%
6.7%
Q3 25
0.6%
6.5%
Q2 25
-21.6%
3.4%
Q1 25
-36.0%
4.1%
Q4 24
-22.1%
6.5%
Q3 24
-17.9%
4.1%
Q2 24
-34.6%
1.3%
Capex Intensity
AXSM
AXSM
TRUP
TRUP
Q1 26
Q4 25
0.0%
1.0%
Q3 25
0.0%
1.4%
Q2 25
0.0%
0.8%
Q1 25
0.3%
0.6%
Q4 24
0.0%
0.6%
Q3 24
0.1%
0.6%
Q2 24
0.1%
0.9%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Product sales, net$189.4M99%
Royalty revenue and milestone revenue$1.8M1%

TRUP
TRUP

Subscriptionbusiness$261.4M69%
Other$115.4M31%

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