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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and Wheels Up Experience Inc. (UP). Click either name above to swap in a different company.
Axsome Therapeutics, Inc. is the larger business by last-quarter revenue ($196.0M vs $183.8M, roughly 1.1× Wheels Up Experience Inc.). Axsome Therapeutics, Inc. runs the higher net margin — -14.6% vs -15.7%, a 1.1% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs -10.2%). Axsome Therapeutics, Inc. produced more free cash flow last quarter ($-18.7M vs $-58.3M). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs -3.4%).
Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.
Wheels Up is a provider of "on demand" private aviation in the United States and one of the largest private aviation companies in the world. It was founded in 2013 by Kenny Dichter, using a membership/on-demand business model. Wheels Up members can book private aircraft from the company fleet and third-party operators using a mobile application.
AXSM vs UP — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $196.0M | $183.8M |
| Net Profit | $-28.6M | $-28.9M |
| Gross Margin | — | 14.3% |
| Operating Margin | -13.8% | -0.9% |
| Net Margin | -14.6% | -15.7% |
| Revenue YoY | 65.0% | -10.2% |
| Net Profit YoY | 61.9% | 67.0% |
| EPS (diluted) | $-0.55 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $196.0M | $183.8M | ||
| Q3 25 | $171.0M | $185.5M | ||
| Q2 25 | $150.0M | $189.6M | ||
| Q1 25 | $121.5M | $177.5M | ||
| Q4 24 | $118.8M | $204.8M | ||
| Q3 24 | $104.8M | $193.9M | ||
| Q2 24 | $87.2M | $196.3M | ||
| Q1 24 | $75.0M | $197.1M |
| Q4 25 | $-28.6M | $-28.9M | ||
| Q3 25 | $-47.2M | $-83.7M | ||
| Q2 25 | $-48.0M | $-82.3M | ||
| Q1 25 | $-59.4M | $-99.3M | ||
| Q4 24 | $-74.9M | $-87.5M | ||
| Q3 24 | $-64.6M | $-57.7M | ||
| Q2 24 | $-79.3M | $-97.0M | ||
| Q1 24 | $-68.4M | $-97.4M |
| Q4 25 | — | 14.3% | ||
| Q3 25 | — | 6.8% | ||
| Q2 25 | — | 8.3% | ||
| Q1 25 | — | 10.8% | ||
| Q4 24 | — | 13.9% | ||
| Q3 24 | — | 13.9% | ||
| Q2 24 | — | 2.3% | ||
| Q1 24 | — | -0.6% |
| Q4 25 | -13.8% | -0.9% | ||
| Q3 25 | -27.0% | -33.1% | ||
| Q2 25 | -24.5% | -31.4% | ||
| Q1 25 | -46.9% | -45.5% | ||
| Q4 24 | -61.1% | -26.0% | ||
| Q3 24 | -59.8% | -21.6% | ||
| Q2 24 | -89.5% | -40.3% | ||
| Q1 24 | -89.7% | -42.9% |
| Q4 25 | -14.6% | -15.7% | ||
| Q3 25 | -27.6% | -45.1% | ||
| Q2 25 | -32.0% | -43.4% | ||
| Q1 25 | -48.9% | -55.9% | ||
| Q4 24 | -63.1% | -42.7% | ||
| Q3 24 | -61.7% | -29.8% | ||
| Q2 24 | -91.0% | -49.4% | ||
| Q1 24 | -91.1% | -49.4% |
| Q4 25 | $-0.55 | $-0.04 | ||
| Q3 25 | $-0.94 | $-0.12 | ||
| Q2 25 | $-0.97 | $-0.12 | ||
| Q1 25 | $-1.22 | $-0.14 | ||
| Q4 24 | $-1.54 | $-0.13 | ||
| Q3 24 | $-1.34 | $-0.08 | ||
| Q2 24 | $-1.67 | $-0.14 | ||
| Q1 24 | $-1.44 | $-0.14 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $322.9M | $133.9M |
| Total DebtLower is stronger | — | $671.3M |
| Stockholders' EquityBook value | $88.3M | $-392.1M |
| Total Assets | $689.8M | $968.8M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $322.9M | $133.9M | ||
| Q3 25 | $325.3M | $125.3M | ||
| Q2 25 | $303.0M | $107.0M | ||
| Q1 25 | $300.9M | $171.8M | ||
| Q4 24 | $315.4M | $216.4M | ||
| Q3 24 | $327.3M | $115.9M | ||
| Q2 24 | $315.7M | $141.5M | ||
| Q1 24 | $331.4M | $180.9M |
| Q4 25 | — | $671.3M | ||
| Q3 25 | — | $766.5M | ||
| Q2 25 | — | $770.5M | ||
| Q1 25 | — | $765.8M | ||
| Q4 24 | — | $761.3M | ||
| Q3 24 | — | $596.9M | ||
| Q2 24 | — | $597.4M | ||
| Q1 24 | — | $603.2M |
| Q4 25 | $88.3M | $-392.1M | ||
| Q3 25 | $73.7M | $-374.5M | ||
| Q2 25 | $73.1M | $-347.8M | ||
| Q1 25 | $53.2M | $-288.1M | ||
| Q4 24 | $57.0M | $-202.1M | ||
| Q3 24 | $92.9M | $-117.7M | ||
| Q2 24 | $102.9M | $-72.2M | ||
| Q1 24 | $144.0M | $936.0K |
| Q4 25 | $689.8M | $968.8M | ||
| Q3 25 | $669.3M | $973.0M | ||
| Q2 25 | $639.8M | $1.0B | ||
| Q1 25 | $596.7M | $1.1B | ||
| Q4 24 | $568.5M | $1.2B | ||
| Q3 24 | $561.5M | $1.0B | ||
| Q2 24 | $548.2M | $1.1B | ||
| Q1 24 | $545.7M | $1.2B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | 644.43× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-18.7M | $-18.4M |
| Free Cash FlowOCF − Capex | $-18.7M | $-58.3M |
| FCF MarginFCF / Revenue | -9.6% | -31.7% |
| Capex IntensityCapex / Revenue | 0.0% | 21.7% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-93.9M | $-259.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-18.7M | $-18.4M | ||
| Q3 25 | $1.0M | $-37.1M | ||
| Q2 25 | $-32.4M | $-62.9M | ||
| Q1 25 | $-43.4M | $-47.9M | ||
| Q4 24 | $-26.2M | $37.9M | ||
| Q3 24 | $-18.6M | $-16.9M | ||
| Q2 24 | $-30.1M | $-25.2M | ||
| Q1 24 | $-53.5M | $-73.8M |
| Q4 25 | $-18.7M | $-58.3M | ||
| Q3 25 | $988.0K | $-60.4M | ||
| Q2 25 | $-32.4M | $-78.6M | ||
| Q1 25 | $-43.7M | $-62.6M | ||
| Q4 24 | $-26.2M | $-70.2M | ||
| Q3 24 | $-18.7M | $-21.9M | ||
| Q2 24 | $-30.2M | $-30.8M | ||
| Q1 24 | $-53.6M | $-77.8M |
| Q4 25 | -9.6% | -31.7% | ||
| Q3 25 | 0.6% | -32.6% | ||
| Q2 25 | -21.6% | -41.5% | ||
| Q1 25 | -36.0% | -35.3% | ||
| Q4 24 | -22.1% | -34.3% | ||
| Q3 24 | -17.9% | -11.3% | ||
| Q2 24 | -34.6% | -15.7% | ||
| Q1 24 | -71.4% | -39.5% |
| Q4 25 | 0.0% | 21.7% | ||
| Q3 25 | 0.0% | 12.5% | ||
| Q2 25 | 0.0% | 8.3% | ||
| Q1 25 | 0.3% | 8.3% | ||
| Q4 24 | 0.0% | 52.8% | ||
| Q3 24 | 0.1% | 2.6% | ||
| Q2 24 | 0.1% | 2.9% | ||
| Q1 24 | 0.1% | 2.0% |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
