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Side-by-side financial comparison of BICYCLE THERAPEUTICS PLC (BCYC) and COMMUNITY TRUST BANCORP INC (CTBI). Click either name above to swap in a different company.

COMMUNITY TRUST BANCORP INC is the larger business by last-quarter revenue ($74.7M vs $48.0M, roughly 1.6× BICYCLE THERAPEUTICS PLC). COMMUNITY TRUST BANCORP INC runs the higher net margin — 36.5% vs -42.0%, a 78.5% gap on every dollar of revenue. On growth, BICYCLE THERAPEUTICS PLC posted the faster year-over-year revenue change (1193.3% vs 13.8%). COMMUNITY TRUST BANCORP INC produced more free cash flow last quarter ($97.4M vs $-19.9M). Over the past eight quarters, BICYCLE THERAPEUTICS PLC's revenue compounded faster (56.7% CAGR vs 12.8%).

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical firm developing innovative bicyclic peptide therapies for unmet medical needs. Its core pipeline covers oncology, rare diseases, and immunological disorders, with operations in Europe and North America, and partnerships with global pharma leaders to advance drug candidates to market.

Community Trust Bancorp is an American regional bank holding company that was founded in 1903 as Pikeville National Bank. The renamed corporation continues to have its headquarters in Pikeville, Kentucky, at the heart of Appalachia. Community Trust Bancorp operates a commercial bank, Community Trust Bank, and a trust company, Community Trust and Investment Company of Lexington.

BCYC vs CTBI — Head-to-Head

Bigger by revenue
CTBI
CTBI
1.6× larger
CTBI
$74.7M
$48.0M
BCYC
Growing faster (revenue YoY)
BCYC
BCYC
+1179.5% gap
BCYC
1193.3%
13.8%
CTBI
Higher net margin
CTBI
CTBI
78.5% more per $
CTBI
36.5%
-42.0%
BCYC
More free cash flow
CTBI
CTBI
$117.3M more FCF
CTBI
$97.4M
$-19.9M
BCYC
Faster 2-yr revenue CAGR
BCYC
BCYC
Annualised
BCYC
56.7%
12.8%
CTBI

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BCYC
BCYC
CTBI
CTBI
Revenue
$48.0M
$74.7M
Net Profit
$-20.2M
$27.3M
Gross Margin
Operating Margin
-51.5%
47.3%
Net Margin
-42.0%
36.5%
Revenue YoY
1193.3%
13.8%
Net Profit YoY
61.1%
21.3%
EPS (diluted)
$-0.29
$1.51

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BCYC
BCYC
CTBI
CTBI
Q4 25
$48.0M
$74.7M
Q3 25
$11.7M
$71.5M
Q2 25
$2.9M
$70.2M
Q1 25
$10.0M
$66.2M
Q4 24
$3.7M
$65.7M
Q3 24
$2.7M
$62.8M
Q2 24
$9.4M
$61.4M
Q1 24
$19.5M
$58.7M
Net Profit
BCYC
BCYC
CTBI
CTBI
Q4 25
$-20.2M
$27.3M
Q3 25
$-59.1M
$23.9M
Q2 25
$-79.0M
$24.9M
Q1 25
$-60.8M
$22.0M
Q4 24
$22.5M
Q3 24
$-50.8M
$22.1M
Q2 24
$-39.8M
$19.5M
Q1 24
$-26.6M
$18.7M
Operating Margin
BCYC
BCYC
CTBI
CTBI
Q4 25
-51.5%
47.3%
Q3 25
-558.6%
43.2%
Q2 25
-2965.8%
46.2%
Q1 25
-703.7%
42.9%
Q4 24
44.7%
Q3 24
-2385.9%
43.8%
Q2 24
-498.3%
42.3%
Q1 24
-162.4%
40.6%
Net Margin
BCYC
BCYC
CTBI
CTBI
Q4 25
-42.0%
36.5%
Q3 25
-503.7%
33.4%
Q2 25
-2703.8%
35.5%
Q1 25
-608.9%
33.2%
Q4 24
34.2%
Q3 24
-1898.4%
35.3%
Q2 24
-425.3%
31.8%
Q1 24
-136.0%
31.8%
EPS (diluted)
BCYC
BCYC
CTBI
CTBI
Q4 25
$-0.29
$1.51
Q3 25
$-0.85
$1.32
Q2 25
$-1.14
$1.38
Q1 25
$-0.88
$1.22
Q4 24
$1.25
Q3 24
$-0.74
$1.23
Q2 24
$-0.77
$1.09
Q1 24
$-0.62
$1.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BCYC
BCYC
CTBI
CTBI
Cash + ST InvestmentsLiquidity on hand
$628.1M
$363.7M
Total DebtLower is stronger
$63.8M
Stockholders' EquityBook value
$610.0M
$856.1M
Total Assets
$717.6M
$6.7B
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BCYC
BCYC
CTBI
CTBI
Q4 25
$628.1M
$363.7M
Q3 25
$648.3M
$507.6M
Q2 25
$721.5M
$395.3M
Q1 25
$793.0M
$340.7M
Q4 24
$879.5M
$369.5M
Q3 24
$890.9M
$240.9M
Q2 24
$961.4M
$161.7M
Q1 24
$457.0M
$293.3M
Total Debt
BCYC
BCYC
CTBI
CTBI
Q4 25
$63.8M
Q3 25
Q2 25
Q1 25
Q4 24
$64.0M
Q3 24
Q2 24
$30.9M
Q1 24
$30.8M
Stockholders' Equity
BCYC
BCYC
CTBI
CTBI
Q4 25
$610.0M
$856.1M
Q3 25
$618.5M
$831.4M
Q2 25
$668.9M
$806.9M
Q1 25
$740.3M
$784.2M
Q4 24
$793.1M
$757.6M
Q3 24
$831.0M
$760.8M
Q2 24
$873.8M
$719.3M
Q1 24
$356.0M
$707.7M
Total Assets
BCYC
BCYC
CTBI
CTBI
Q4 25
$717.6M
$6.7B
Q3 25
$764.0M
$6.6B
Q2 25
$832.2M
$6.4B
Q1 25
$883.9M
$6.3B
Q4 24
$956.9M
$6.2B
Q3 24
$996.7M
$6.0B
Q2 24
$1.1B
$5.8B
Q1 24
$547.1M
$5.9B
Debt / Equity
BCYC
BCYC
CTBI
CTBI
Q4 25
0.07×
Q3 25
Q2 25
Q1 25
Q4 24
0.08×
Q3 24
Q2 24
0.04×
Q1 24
0.09×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BCYC
BCYC
CTBI
CTBI
Operating Cash FlowLast quarter
$-19.3M
$105.0M
Free Cash FlowOCF − Capex
$-19.9M
$97.4M
FCF MarginFCF / Revenue
-41.5%
130.3%
Capex IntensityCapex / Revenue
1.2%
10.2%
Cash ConversionOCF / Net Profit
3.85×
TTM Free Cash FlowTrailing 4 quarters
$-252.0M
$181.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BCYC
BCYC
CTBI
CTBI
Q4 25
$-19.3M
$105.0M
Q3 25
$-71.2M
$37.5M
Q2 25
$-72.8M
$15.9M
Q1 25
$-86.4M
$36.6M
Q4 24
$-164.7M
$105.3M
Q3 24
$-39.8M
$36.7M
Q2 24
$-44.6M
$20.0M
Q1 24
$-70.9M
$26.2M
Free Cash Flow
BCYC
BCYC
CTBI
CTBI
Q4 25
$-19.9M
$97.4M
Q3 25
$-71.8M
$36.4M
Q2 25
$-73.3M
$13.6M
Q1 25
$-87.0M
$34.5M
Q4 24
$-166.0M
$97.2M
Q3 24
$-40.3M
$35.4M
Q2 24
$-45.0M
$18.4M
Q1 24
$-70.9M
$24.0M
FCF Margin
BCYC
BCYC
CTBI
CTBI
Q4 25
-41.5%
130.3%
Q3 25
-612.3%
50.8%
Q2 25
-2509.7%
19.3%
Q1 25
-871.7%
52.2%
Q4 24
-4475.7%
148.0%
Q3 24
-1504.7%
56.4%
Q2 24
-481.2%
30.1%
Q1 24
-362.9%
40.9%
Capex Intensity
BCYC
BCYC
CTBI
CTBI
Q4 25
1.2%
10.2%
Q3 25
5.7%
1.7%
Q2 25
17.1%
3.4%
Q1 25
6.1%
3.1%
Q4 24
33.3%
12.3%
Q3 24
16.3%
2.1%
Q2 24
4.5%
2.5%
Q1 24
0.1%
3.7%
Cash Conversion
BCYC
BCYC
CTBI
CTBI
Q4 25
3.85×
Q3 25
1.57×
Q2 25
0.64×
Q1 25
1.66×
Q4 24
4.68×
Q3 24
1.66×
Q2 24
1.02×
Q1 24
1.40×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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