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Side-by-side financial comparison of BICYCLE THERAPEUTICS PLC (BCYC) and Neptune Insurance Holdings Inc. (NP). Click either name above to swap in a different company.

BICYCLE THERAPEUTICS PLC is the larger business by last-quarter revenue ($48.0M vs $37.8M, roughly 1.3× Neptune Insurance Holdings Inc.). Neptune Insurance Holdings Inc. runs the higher net margin — 0.1% vs -42.0%, a 42.2% gap on every dollar of revenue. On growth, BICYCLE THERAPEUTICS PLC posted the faster year-over-year revenue change (1193.3% vs 28.8%).

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical firm developing innovative bicyclic peptide therapies for unmet medical needs. Its core pipeline covers oncology, rare diseases, and immunological disorders, with operations in Europe and North America, and partnerships with global pharma leaders to advance drug candidates to market.

Neptune Insurance Holdings Inc. is a specialty insurance holding company that offers a broad portfolio of property and casualty insurance products, with a core focus on residential and commercial flood insurance for customers across the United States. It serves both individual consumers and small to mid-sized business clients, using advanced data analytics to support accurate policy pricing and robust risk management.

BCYC vs NP — Head-to-Head

Bigger by revenue
BCYC
BCYC
1.3× larger
BCYC
$48.0M
$37.8M
NP
Growing faster (revenue YoY)
BCYC
BCYC
+1164.5% gap
BCYC
1193.3%
28.8%
NP
Higher net margin
NP
NP
42.2% more per $
NP
0.1%
-42.0%
BCYC

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
BCYC
BCYC
NP
NP
Revenue
$48.0M
$37.8M
Net Profit
$-20.2M
$50.0K
Gross Margin
Operating Margin
-51.5%
Net Margin
-42.0%
0.1%
Revenue YoY
1193.3%
28.8%
Net Profit YoY
61.1%
0.0%
EPS (diluted)
$-0.29
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BCYC
BCYC
NP
NP
Q1 26
$37.8M
Q4 25
$48.0M
Q3 25
$11.7M
$44.4M
Q2 25
$2.9M
Q1 25
$10.0M
Q4 24
$3.7M
Q3 24
$2.7M
$33.8M
Q2 24
$9.4M
Net Profit
BCYC
BCYC
NP
NP
Q1 26
$50.0K
Q4 25
$-20.2M
Q3 25
$-59.1M
$11.5M
Q2 25
$-79.0M
Q1 25
$-60.8M
Q4 24
Q3 24
$-50.8M
$12.1M
Q2 24
$-39.8M
Operating Margin
BCYC
BCYC
NP
NP
Q1 26
Q4 25
-51.5%
Q3 25
-558.6%
46.7%
Q2 25
-2965.8%
Q1 25
-703.7%
Q4 24
Q3 24
-2385.9%
58.6%
Q2 24
-498.3%
Net Margin
BCYC
BCYC
NP
NP
Q1 26
0.1%
Q4 25
-42.0%
Q3 25
-503.7%
25.9%
Q2 25
-2703.8%
Q1 25
-608.9%
Q4 24
Q3 24
-1898.4%
35.8%
Q2 24
-425.3%
EPS (diluted)
BCYC
BCYC
NP
NP
Q1 26
$0.05
Q4 25
$-0.29
Q3 25
$-0.85
$0.06
Q2 25
$-1.14
Q1 25
$-0.88
Q4 24
Q3 24
$-0.74
$0.06
Q2 24
$-0.77

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BCYC
BCYC
NP
NP
Cash + ST InvestmentsLiquidity on hand
$628.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$610.0M
Total Assets
$717.6M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BCYC
BCYC
NP
NP
Q1 26
Q4 25
$628.1M
Q3 25
$648.3M
$12.2M
Q2 25
$721.5M
Q1 25
$793.0M
Q4 24
$879.5M
Q3 24
$890.9M
Q2 24
$961.4M
Total Debt
BCYC
BCYC
NP
NP
Q1 26
Q4 25
Q3 25
$247.6M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
$30.9M
Stockholders' Equity
BCYC
BCYC
NP
NP
Q1 26
Q4 25
$610.0M
Q3 25
$618.5M
$-509.5M
Q2 25
$668.9M
Q1 25
$740.3M
Q4 24
$793.1M
Q3 24
$831.0M
$-374.3M
Q2 24
$873.8M
Total Assets
BCYC
BCYC
NP
NP
Q1 26
Q4 25
$717.6M
Q3 25
$764.0M
$89.6M
Q2 25
$832.2M
Q1 25
$883.9M
Q4 24
$956.9M
Q3 24
$996.7M
Q2 24
$1.1B
Debt / Equity
BCYC
BCYC
NP
NP
Q1 26
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BCYC
BCYC
NP
NP
Operating Cash FlowLast quarter
$-19.3M
Free Cash FlowOCF − Capex
$-19.9M
FCF MarginFCF / Revenue
-41.5%
Capex IntensityCapex / Revenue
1.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-252.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BCYC
BCYC
NP
NP
Q1 26
Q4 25
$-19.3M
Q3 25
$-71.2M
$38.9M
Q2 25
$-72.8M
Q1 25
$-86.4M
Q4 24
$-164.7M
Q3 24
$-39.8M
Q2 24
$-44.6M
Free Cash Flow
BCYC
BCYC
NP
NP
Q1 26
Q4 25
$-19.9M
Q3 25
$-71.8M
Q2 25
$-73.3M
Q1 25
$-87.0M
Q4 24
$-166.0M
Q3 24
$-40.3M
Q2 24
$-45.0M
FCF Margin
BCYC
BCYC
NP
NP
Q1 26
Q4 25
-41.5%
Q3 25
-612.3%
Q2 25
-2509.7%
Q1 25
-871.7%
Q4 24
-4475.7%
Q3 24
-1504.7%
Q2 24
-481.2%
Capex Intensity
BCYC
BCYC
NP
NP
Q1 26
Q4 25
1.2%
Q3 25
5.7%
Q2 25
17.1%
Q1 25
6.1%
Q4 24
33.3%
Q3 24
16.3%
Q2 24
4.5%
Cash Conversion
BCYC
BCYC
NP
NP
Q1 26
Q4 25
Q3 25
3.38×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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