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Side-by-side financial comparison of BICYCLE THERAPEUTICS PLC (BCYC) and SOUTHERN FIRST BANCSHARES INC (SFST). Click either name above to swap in a different company.
BICYCLE THERAPEUTICS PLC is the larger business by last-quarter revenue ($48.0M vs $31.8M, roughly 1.5× SOUTHERN FIRST BANCSHARES INC). On growth, BICYCLE THERAPEUTICS PLC posted the faster year-over-year revenue change (1193.3% vs 26.1%). SOUTHERN FIRST BANCSHARES INC produced more free cash flow last quarter ($29.9M vs $-19.9M). Over the past eight quarters, BICYCLE THERAPEUTICS PLC's revenue compounded faster (56.7% CAGR vs 22.2%).
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical firm developing innovative bicyclic peptide therapies for unmet medical needs. Its core pipeline covers oncology, rare diseases, and immunological disorders, with operations in Europe and North America, and partnerships with global pharma leaders to advance drug candidates to market.
First Community Bankshares, Inc. is a $2.43 billion bank holding company and the parent company of First Community Bank of Bluefield, Virginia, in the United States. As of 2012 First Community Bank had 45 locations in Virginia, West Virginia, and North Carolina, and two locations operating as Peoples Community Bank in Tennessee. As of April 21, 2023, First Community had $3.6 billion in assets.
BCYC vs SFST — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $48.0M | $31.8M |
| Net Profit | $-20.2M | — |
| Gross Margin | — | — |
| Operating Margin | -51.5% | 40.1% |
| Net Margin | -42.0% | — |
| Revenue YoY | 1193.3% | 26.1% |
| Net Profit YoY | 61.1% | — |
| EPS (diluted) | $-0.29 | $1.19 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $48.0M | $31.8M | ||
| Q3 25 | $11.7M | $31.1M | ||
| Q2 25 | $2.9M | $28.6M | ||
| Q1 25 | $10.0M | $26.5M | ||
| Q4 24 | $3.7M | $25.2M | ||
| Q3 24 | $2.7M | $23.8M | ||
| Q2 24 | $9.4M | $23.1M | ||
| Q1 24 | $19.5M | $21.3M |
| Q4 25 | $-20.2M | — | ||
| Q3 25 | $-59.1M | $8.7M | ||
| Q2 25 | $-79.0M | $6.6M | ||
| Q1 25 | $-60.8M | $5.3M | ||
| Q4 24 | — | — | ||
| Q3 24 | $-50.8M | $4.4M | ||
| Q2 24 | $-39.8M | $3.0M | ||
| Q1 24 | $-26.6M | $2.5M |
| Q4 25 | -51.5% | 40.1% | ||
| Q3 25 | -558.6% | 36.4% | ||
| Q2 25 | -2965.8% | 30.0% | ||
| Q1 25 | -703.7% | 26.1% | ||
| Q4 24 | — | 27.3% | ||
| Q3 24 | -2385.9% | 24.1% | ||
| Q2 24 | -498.3% | 17.0% | ||
| Q1 24 | -162.4% | 15.9% |
| Q4 25 | -42.0% | — | ||
| Q3 25 | -503.7% | 27.8% | ||
| Q2 25 | -2703.8% | 23.0% | ||
| Q1 25 | -608.9% | 19.9% | ||
| Q4 24 | — | — | ||
| Q3 24 | -1898.4% | 18.4% | ||
| Q2 24 | -425.3% | 13.0% | ||
| Q1 24 | -136.0% | 11.8% |
| Q4 25 | $-0.29 | $1.19 | ||
| Q3 25 | $-0.85 | $1.07 | ||
| Q2 25 | $-1.14 | $0.81 | ||
| Q1 25 | $-0.88 | $0.65 | ||
| Q4 24 | — | $0.69 | ||
| Q3 24 | $-0.74 | $0.54 | ||
| Q2 24 | $-0.77 | $0.37 | ||
| Q1 24 | $-0.62 | $0.31 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $628.1M | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $610.0M | $368.7M |
| Total Assets | $717.6M | $4.4B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $628.1M | — | ||
| Q3 25 | $648.3M | — | ||
| Q2 25 | $721.5M | — | ||
| Q1 25 | $793.0M | — | ||
| Q4 24 | $879.5M | — | ||
| Q3 24 | $890.9M | — | ||
| Q2 24 | $961.4M | — | ||
| Q1 24 | $457.0M | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | $30.9M | — | ||
| Q1 24 | $30.8M | — |
| Q4 25 | $610.0M | $368.7M | ||
| Q3 25 | $618.5M | $356.3M | ||
| Q2 25 | $668.9M | $345.5M | ||
| Q1 25 | $740.3M | $337.6M | ||
| Q4 24 | $793.1M | $330.4M | ||
| Q3 24 | $831.0M | $326.5M | ||
| Q2 24 | $873.8M | $318.7M | ||
| Q1 24 | $356.0M | $315.3M |
| Q4 25 | $717.6M | $4.4B | ||
| Q3 25 | $764.0M | $4.4B | ||
| Q2 25 | $832.2M | $4.3B | ||
| Q1 25 | $883.9M | $4.3B | ||
| Q4 24 | $956.9M | $4.1B | ||
| Q3 24 | $996.7M | $4.2B | ||
| Q2 24 | $1.1B | $4.1B | ||
| Q1 24 | $547.1M | $4.1B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | 0.04× | — | ||
| Q1 24 | 0.09× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-19.3M | $30.5M |
| Free Cash FlowOCF − Capex | $-19.9M | $29.9M |
| FCF MarginFCF / Revenue | -41.5% | 93.8% |
| Capex IntensityCapex / Revenue | 1.2% | 1.8% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-252.0M | $62.1M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-19.3M | $30.5M | ||
| Q3 25 | $-71.2M | $14.5M | ||
| Q2 25 | $-72.8M | $10.5M | ||
| Q1 25 | $-86.4M | $7.6M | ||
| Q4 24 | $-164.7M | $25.6M | ||
| Q3 24 | $-39.8M | $26.3M | ||
| Q2 24 | $-44.6M | $4.0M | ||
| Q1 24 | $-70.9M | $-2.9M |
| Q4 25 | $-19.9M | $29.9M | ||
| Q3 25 | $-71.8M | $14.4M | ||
| Q2 25 | $-73.3M | $10.4M | ||
| Q1 25 | $-87.0M | $7.4M | ||
| Q4 24 | $-166.0M | $24.8M | ||
| Q3 24 | $-40.3M | $26.1M | ||
| Q2 24 | $-45.0M | $3.9M | ||
| Q1 24 | $-70.9M | $-3.2M |
| Q4 25 | -41.5% | 93.8% | ||
| Q3 25 | -612.3% | 46.3% | ||
| Q2 25 | -2509.7% | 36.3% | ||
| Q1 25 | -871.7% | 28.1% | ||
| Q4 24 | -4475.7% | 98.2% | ||
| Q3 24 | -1504.7% | 110.0% | ||
| Q2 24 | -481.2% | 16.8% | ||
| Q1 24 | -362.9% | -15.0% |
| Q4 25 | 1.2% | 1.8% | ||
| Q3 25 | 5.7% | 0.3% | ||
| Q2 25 | 17.1% | 0.3% | ||
| Q1 25 | 6.1% | 0.5% | ||
| Q4 24 | 33.3% | 3.1% | ||
| Q3 24 | 16.3% | 0.8% | ||
| Q2 24 | 4.5% | 0.4% | ||
| Q1 24 | 0.1% | 1.3% |
| Q4 25 | — | — | ||
| Q3 25 | — | 1.67× | ||
| Q2 25 | — | 1.59× | ||
| Q1 25 | — | 1.44× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 6.01× | ||
| Q2 24 | — | 1.32× | ||
| Q1 24 | — | -1.16× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
