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Side-by-side financial comparison of Biogen (BIIB) and GRAPHIC PACKAGING HOLDING CO (GPK). Click either name above to swap in a different company.

Biogen is the larger business by last-quarter revenue ($2.3B vs $2.1B, roughly 1.1× GRAPHIC PACKAGING HOLDING CO). GRAPHIC PACKAGING HOLDING CO runs the higher net margin — 3.4% vs -2.1%, a 5.5% gap on every dollar of revenue. On growth, GRAPHIC PACKAGING HOLDING CO posted the faster year-over-year revenue change (0.2% vs -7.1%). Over the past eight quarters, Biogen's revenue compounded faster (-0.2% CAGR vs -3.5%).

Biogen Inc. is an American multinational biotechnology company based in Cambridge, Massachusetts, United States specializing in the treatment of neurological diseases. The company's primary products are dimethyl fumarate (Tecfidera), diroximel fumarate (Vumerity), interferon beta-1a (AVONEX), peginterferon beta-1a (Plegridy), and natalizumab (Tysabri), all for the treatment of multiple sclerosis ; nusinersen (Spinraza) for the treatment of spinal muscular atrophy ; omaveloxolone (Skyclarys) for ...

Graphic Packaging International is a Fortune 500 corporation based in Atlanta, Georgia, United States. It designs and manufactures packaging solutions for commercial products. GPI manufactures paperboard and folding cartons for a wide range of popular consumer goods, particularly beverages and packaged food. The company operates paperboard mills in Kalamazoo, Michigan; Macon, Georgia; Middletown, Ohio; Prosperity, South Carolina; Texarkana, Texas; and West Monroe, Louisiana, that use recycled...

BIIB vs GPK — Head-to-Head

Bigger by revenue
BIIB
BIIB
1.1× larger
BIIB
$2.3B
$2.1B
GPK
Growing faster (revenue YoY)
GPK
GPK
+7.4% gap
GPK
0.2%
-7.1%
BIIB
Higher net margin
GPK
GPK
5.5% more per $
GPK
3.4%
-2.1%
BIIB
Faster 2-yr revenue CAGR
BIIB
BIIB
Annualised
BIIB
-0.2%
-3.5%
GPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BIIB
BIIB
GPK
GPK
Revenue
$2.3B
$2.1B
Net Profit
$-48.9M
$71.0M
Gross Margin
78.3%
14.1%
Operating Margin
-2.5%
7.4%
Net Margin
-2.1%
3.4%
Revenue YoY
-7.1%
0.2%
Net Profit YoY
-118.3%
-48.6%
EPS (diluted)
$-0.35
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BIIB
BIIB
GPK
GPK
Q4 25
$2.3B
$2.1B
Q3 25
$2.5B
$2.2B
Q2 25
$2.6B
$2.2B
Q1 25
$2.4B
$2.1B
Q4 24
$2.5B
$2.1B
Q3 24
$2.5B
$2.2B
Q2 24
$2.5B
$2.2B
Q1 24
$2.3B
$2.3B
Net Profit
BIIB
BIIB
GPK
GPK
Q4 25
$-48.9M
$71.0M
Q3 25
$466.5M
$142.0M
Q2 25
$634.8M
$104.0M
Q1 25
$240.5M
$127.0M
Q4 24
$266.7M
$138.0M
Q3 24
$388.5M
$165.0M
Q2 24
$583.6M
$190.0M
Q1 24
$393.4M
$165.0M
Gross Margin
BIIB
BIIB
GPK
GPK
Q4 25
78.3%
14.1%
Q3 25
73.4%
19.6%
Q2 25
77.1%
18.7%
Q1 25
74.1%
20.6%
Q4 24
76.2%
21.4%
Q3 24
74.1%
22.3%
Q2 24
77.8%
21.2%
Q1 24
76.3%
23.0%
Operating Margin
BIIB
BIIB
GPK
GPK
Q4 25
-2.5%
7.4%
Q3 25
22.0%
10.7%
Q2 25
28.1%
8.8%
Q1 25
12.8%
10.5%
Q4 24
11.9%
11.4%
Q3 24
18.3%
12.6%
Q2 24
28.3%
14.5%
Q1 24
20.3%
12.4%
Net Margin
BIIB
BIIB
GPK
GPK
Q4 25
-2.1%
3.4%
Q3 25
18.4%
6.5%
Q2 25
24.0%
4.7%
Q1 25
9.9%
6.0%
Q4 24
10.9%
6.6%
Q3 24
15.8%
7.5%
Q2 24
23.7%
8.5%
Q1 24
17.2%
7.3%
EPS (diluted)
BIIB
BIIB
GPK
GPK
Q4 25
$-0.35
$0.24
Q3 25
$3.17
$0.48
Q2 25
$4.33
$0.34
Q1 25
$1.64
$0.42
Q4 24
$1.82
$0.46
Q3 24
$2.66
$0.55
Q2 24
$4.00
$0.62
Q1 24
$2.70
$0.53

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BIIB
BIIB
GPK
GPK
Cash + ST InvestmentsLiquidity on hand
$261.0M
Total DebtLower is stronger
$6.3B
$5.0B
Stockholders' EquityBook value
$18.3B
$3.3B
Total Assets
$29.4B
$11.8B
Debt / EquityLower = less leverage
0.34×
1.51×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BIIB
BIIB
GPK
GPK
Q4 25
$261.0M
Q3 25
$120.0M
Q2 25
$120.0M
Q1 25
$129.0M
Q4 24
$157.0M
Q3 24
$126.0M
Q2 24
$125.0M
Q1 24
$136.0M
Total Debt
BIIB
BIIB
GPK
GPK
Q4 25
$6.3B
$5.0B
Q3 25
$6.3B
$5.5B
Q2 25
$6.3B
$5.4B
Q1 25
$4.5B
$5.7B
Q4 24
$6.3B
$5.1B
Q3 24
$4.5B
$5.4B
Q2 24
$6.3B
$4.9B
Q1 24
$6.3B
$4.9B
Stockholders' Equity
BIIB
BIIB
GPK
GPK
Q4 25
$18.3B
$3.3B
Q3 25
$18.2B
$3.3B
Q2 25
$17.6B
$3.2B
Q1 25
$17.0B
$3.2B
Q4 24
$16.7B
$3.0B
Q3 24
$16.4B
$3.0B
Q2 24
$15.9B
$2.8B
Q1 24
$15.2B
$2.9B
Total Assets
BIIB
BIIB
GPK
GPK
Q4 25
$29.4B
$11.8B
Q3 25
$29.2B
$11.9B
Q2 25
$28.3B
$11.8B
Q1 25
$28.0B
$11.5B
Q4 24
$28.0B
$11.1B
Q3 24
$28.3B
$11.2B
Q2 24
$26.8B
$10.8B
Q1 24
$26.6B
$11.3B
Debt / Equity
BIIB
BIIB
GPK
GPK
Q4 25
0.34×
1.51×
Q3 25
0.35×
1.67×
Q2 25
0.36×
1.68×
Q1 25
0.27×
1.80×
Q4 24
0.38×
1.71×
Q3 24
0.28×
1.79×
Q2 24
0.40×
1.75×
Q1 24
0.41×
1.73×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BIIB
BIIB
GPK
GPK
Operating Cash FlowLast quarter
$511.9M
$521.0M
Free Cash FlowOCF − Capex
$468.0M
FCF MarginFCF / Revenue
20.5%
Capex IntensityCapex / Revenue
1.9%
Cash ConversionOCF / Net Profit
7.34×
TTM Free Cash FlowTrailing 4 quarters
$2.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BIIB
BIIB
GPK
GPK
Q4 25
$511.9M
$521.0M
Q3 25
$1.3B
$227.0M
Q2 25
$160.9M
$267.0M
Q1 25
$259.3M
$-174.0M
Q4 24
$760.9M
$489.0M
Q3 24
$935.6M
$187.0M
Q2 24
$625.8M
$161.0M
Q1 24
$553.2M
$3.0M
Free Cash Flow
BIIB
BIIB
GPK
GPK
Q4 25
$468.0M
Q3 25
$1.2B
Q2 25
$134.3M
Q1 25
$222.2M
Q4 24
$721.6M
Q3 24
$900.6M
Q2 24
$592.3M
Q1 24
$507.3M
FCF Margin
BIIB
BIIB
GPK
GPK
Q4 25
20.5%
Q3 25
48.4%
Q2 25
5.1%
Q1 25
9.1%
Q4 24
29.4%
Q3 24
36.5%
Q2 24
24.0%
Q1 24
22.1%
Capex Intensity
BIIB
BIIB
GPK
GPK
Q4 25
1.9%
Q3 25
1.8%
Q2 25
1.0%
Q1 25
1.5%
Q4 24
1.6%
Q3 24
1.4%
Q2 24
1.4%
Q1 24
2.0%
Cash Conversion
BIIB
BIIB
GPK
GPK
Q4 25
7.34×
Q3 25
2.73×
1.60×
Q2 25
0.25×
2.57×
Q1 25
1.08×
-1.37×
Q4 24
2.85×
3.54×
Q3 24
2.41×
1.13×
Q2 24
1.07×
0.85×
Q1 24
1.41×
0.02×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BIIB
BIIB

Products$1.7B73%
Tysabri Product$244.5M11%
AVONEX$119.2M5%
SKYCLARYS$88.9M4%
Alzheimers Collaboration$47.1M2%
IMRALDI$43.5M2%
TECFIDERA$36.9M2%
PLEGRIDY$24.7M1%
QALSODY$7.8M0%
BYOOVIZ$4.3M0%

GPK
GPK

Americas Paperboard Packaging$1.4B68%
Other$667.0M32%

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