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Side-by-side financial comparison of COMMERCE BANCSHARES INC (CBSH) and INSMED Inc (INSM). Click either name above to swap in a different company.

COMMERCE BANCSHARES INC is the larger business by last-quarter revenue ($475.7M vs $263.8M, roughly 1.8× INSMED Inc). COMMERCE BANCSHARES INC runs the higher net margin — 29.8% vs -124.5%, a 154.3% gap on every dollar of revenue. On growth, INSMED Inc posted the faster year-over-year revenue change (152.6% vs 11.1%). Over the past eight quarters, INSMED Inc's revenue compounded faster (86.9% CAGR vs 7.1%).

Commerce Bancshares, Inc. is a regional bank holding company headquartered in Missouri, with principal offices in Kansas City and St. Louis. It is the corporate parent of Commerce Bank, which offers a diversified line of financial services, including business and personal banking, wealth management and investments through its affiliated companies.

Insmed Inc. is a global biopharmaceutical firm focused on developing and commercializing innovative therapies for patients with serious rare diseases that have high unmet medical needs. Its key offerings target pulmonary and endocrine rare disorders, serving markets across North America, Europe, and Asia Pacific.

CBSH vs INSM — Head-to-Head

Bigger by revenue
CBSH
CBSH
1.8× larger
CBSH
$475.7M
$263.8M
INSM
Growing faster (revenue YoY)
INSM
INSM
+141.5% gap
INSM
152.6%
11.1%
CBSH
Higher net margin
CBSH
CBSH
154.3% more per $
CBSH
29.8%
-124.5%
INSM
Faster 2-yr revenue CAGR
INSM
INSM
Annualised
INSM
86.9%
7.1%
CBSH

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
CBSH
CBSH
INSM
INSM
Revenue
$475.7M
$263.8M
Net Profit
$141.6M
$-328.5M
Gross Margin
83.2%
Operating Margin
-121.2%
Net Margin
29.8%
-124.5%
Revenue YoY
11.1%
152.6%
Net Profit YoY
10.5%
-39.5%
EPS (diluted)
$0.96
$-1.55

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CBSH
CBSH
INSM
INSM
Q1 26
$475.7M
Q4 25
$449.4M
$263.8M
Q3 25
$441.0M
$142.3M
Q2 25
$445.8M
$107.4M
Q1 25
$428.1M
$92.8M
Q4 24
$422.1M
$104.4M
Q3 24
$421.4M
$93.4M
Q2 24
$414.5M
$90.3M
Net Profit
CBSH
CBSH
INSM
INSM
Q1 26
$141.6M
Q4 25
$140.7M
$-328.5M
Q3 25
$141.5M
$-370.0M
Q2 25
$152.5M
$-321.7M
Q1 25
$131.6M
$-256.6M
Q4 24
$136.1M
$-235.5M
Q3 24
$138.0M
$-220.5M
Q2 24
$139.6M
$-300.6M
Gross Margin
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
83.2%
Q3 25
79.4%
Q2 25
73.9%
Q1 25
77.1%
Q4 24
75.0%
Q3 24
77.3%
Q2 24
76.8%
Operating Margin
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
40.8%
-121.2%
Q3 25
41.9%
-257.1%
Q2 25
44.0%
-291.3%
Q1 25
39.2%
-267.3%
Q4 24
41.2%
-220.6%
Q3 24
42.4%
-228.4%
Q2 24
43.4%
-319.8%
Net Margin
CBSH
CBSH
INSM
INSM
Q1 26
29.8%
Q4 25
31.3%
-124.5%
Q3 25
32.1%
-260.0%
Q2 25
34.2%
-299.5%
Q1 25
30.7%
-276.4%
Q4 24
32.2%
-225.5%
Q3 24
32.8%
-236.0%
Q2 24
33.7%
-332.8%
EPS (diluted)
CBSH
CBSH
INSM
INSM
Q1 26
$0.96
Q4 25
$0.86
$-1.55
Q3 25
$1.06
$-1.75
Q2 25
$1.14
$-1.70
Q1 25
$0.98
$-1.42
Q4 24
$0.83
$-1.30
Q3 24
$1.01
$-1.27
Q2 24
$1.03
$-1.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CBSH
CBSH
INSM
INSM
Cash + ST InvestmentsLiquidity on hand
$1.4B
Total DebtLower is stronger
$546.8M
Stockholders' EquityBook value
$4.3B
$739.0M
Total Assets
$35.7B
$2.3B
Debt / EquityLower = less leverage
0.74×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
$1.4B
Q3 25
$1.7B
Q2 25
$1.9B
Q1 25
$1.2B
Q4 24
$1.4B
Q3 24
$1.5B
Q2 24
$1.2B
Total Debt
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
$546.8M
Q3 25
$546.8M
Q2 25
$546.8M
Q1 25
$1.1B
Q4 24
$1.1B
Q3 24
$971.8M
Q2 24
$1.2B
Stockholders' Equity
CBSH
CBSH
INSM
INSM
Q1 26
$4.3B
Q4 25
$3.8B
$739.0M
Q3 25
$3.8B
$945.6M
Q2 25
$3.6B
$1.2B
Q1 25
$3.5B
$99.2M
Q4 24
$3.3B
$285.4M
Q3 24
$3.4B
$483.4M
Q2 24
$3.1B
$38.8M
Total Assets
CBSH
CBSH
INSM
INSM
Q1 26
$35.7B
Q4 25
$32.9B
$2.3B
Q3 25
$32.3B
$2.4B
Q2 25
$32.3B
$2.5B
Q1 25
$32.4B
$1.8B
Q4 24
$32.0B
$2.0B
Q3 24
$31.5B
$2.1B
Q2 24
$30.6B
$1.8B
Debt / Equity
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
0.74×
Q3 25
0.58×
Q2 25
0.44×
Q1 25
11.31×
Q4 24
3.93×
Q3 24
2.01×
Q2 24
30.66×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CBSH
CBSH
INSM
INSM
Operating Cash FlowLast quarter
$-247.6M
Free Cash FlowOCF − Capex
$-264.2M
FCF MarginFCF / Revenue
-100.1%
Capex IntensityCapex / Revenue
6.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-967.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
$645.1M
$-247.6M
Q3 25
$129.0M
$-219.8M
Q2 25
$111.2M
$-205.6M
Q1 25
$138.6M
$-262.1M
Q4 24
$577.9M
$-196.0M
Q3 24
$431.7M
$-180.9M
Q2 24
$147.4M
$-123.0M
Free Cash Flow
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
$592.4M
$-264.2M
Q3 25
$113.3M
$-222.2M
Q2 25
$100.5M
$-209.1M
Q1 25
$126.0M
$-272.2M
Q4 24
$531.7M
$-202.8M
Q3 24
$419.1M
$-184.6M
Q2 24
$138.9M
$-129.7M
FCF Margin
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
131.8%
-100.1%
Q3 25
25.7%
-156.1%
Q2 25
22.5%
-194.6%
Q1 25
29.4%
-293.2%
Q4 24
126.0%
-194.1%
Q3 24
99.5%
-197.6%
Q2 24
33.5%
-143.6%
Capex Intensity
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
11.7%
6.3%
Q3 25
3.6%
1.7%
Q2 25
2.4%
3.2%
Q1 25
2.9%
10.8%
Q4 24
10.9%
6.5%
Q3 24
3.0%
3.9%
Q2 24
2.1%
7.5%
Cash Conversion
CBSH
CBSH
INSM
INSM
Q1 26
Q4 25
4.59×
Q3 25
0.91×
Q2 25
0.73×
Q1 25
1.05×
Q4 24
4.25×
Q3 24
3.13×
Q2 24
1.06×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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