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Side-by-side financial comparison of Cibus, Inc. (CBUS) and Ensysce Biosciences, Inc. (ENSC). Click either name above to swap in a different company.

Ensysce Biosciences, Inc. is the larger business by last-quarter revenue ($1.9M vs $1.1M, roughly 1.8× Cibus, Inc.). Ensysce Biosciences, Inc. runs the higher net margin — -147.0% vs -2959.9%, a 2812.8% gap on every dollar of revenue. On growth, Ensysce Biosciences, Inc. posted the faster year-over-year revenue change (44.4% vs -12.8%). Over the past eight quarters, Ensysce Biosciences, Inc.'s revenue compounded faster (107.9% CAGR vs 39.3%).

Cibus, Inc. is a leading agricultural biotechnology firm specializing in precision gene editing technologies to develop improved, sustainable crop traits. Its solutions include herbicide tolerance, disease and pest resistance, and enhanced yield characteristics for major row crops, serving global agricultural markets, seed producers, and farming communities to reduce environmental impact and boost operational efficiency.

Ensysce Biosciences, Inc. is a clinical-stage biotechnology firm specializing in developing innovative prodrug therapies for pain management and oncology indications. Its proprietary platform is designed to reduce opioid abuse risks while enhancing treatment efficacy, targeting global healthcare and pharmaceutical markets with a focus on unmet clinical needs.

CBUS vs ENSC — Head-to-Head

Bigger by revenue
ENSC
ENSC
1.8× larger
ENSC
$1.9M
$1.1M
CBUS
Growing faster (revenue YoY)
ENSC
ENSC
+57.2% gap
ENSC
44.4%
-12.8%
CBUS
Higher net margin
ENSC
ENSC
2812.8% more per $
ENSC
-147.0%
-2959.9%
CBUS
Faster 2-yr revenue CAGR
ENSC
ENSC
Annualised
ENSC
107.9%
39.3%
CBUS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CBUS
CBUS
ENSC
ENSC
Revenue
$1.1M
$1.9M
Net Profit
$-31.3M
$-2.8M
Gross Margin
Operating Margin
-2135.7%
-147.8%
Net Margin
-2959.9%
-147.0%
Revenue YoY
-12.8%
44.4%
Net Profit YoY
-35.4%
22.3%
EPS (diluted)
$-0.39
$-0.51

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CBUS
CBUS
ENSC
ENSC
Q4 25
$1.1M
$1.9M
Q3 25
$615.0K
$493.1K
Q2 25
$933.0K
$1.4M
Q1 25
$1.0M
$1.3M
Q4 24
$1.2M
$1.3M
Q3 24
$1.7M
$3.4M
Q2 24
$838.0K
Q1 24
$545.0K
Net Profit
CBUS
CBUS
ENSC
ENSC
Q4 25
$-31.3M
$-2.8M
Q3 25
$-23.5M
$-3.7M
Q2 25
$-25.4M
$-1.7M
Q1 25
$-46.9M
$-1.9M
Q4 24
$-23.1M
$-3.6M
Q3 24
$-180.0M
$661.8K
Q2 24
$-24.9M
Q1 24
$-23.4M
Operating Margin
CBUS
CBUS
ENSC
ENSC
Q4 25
-2135.7%
-147.8%
Q3 25
-2510.2%
-758.7%
Q2 25
-1923.5%
-127.6%
Q1 25
-4020.4%
-149.1%
Q4 24
-1487.1%
-274.3%
Q3 24
-12023.8%
18.9%
Q2 24
-2563.5%
Q1 24
-3385.9%
Net Margin
CBUS
CBUS
ENSC
ENSC
Q4 25
-2959.9%
-147.0%
Q3 25
-3827.8%
-756.3%
Q2 25
-2719.4%
-126.4%
Q1 25
-4534.4%
-147.4%
Q4 24
-1906.1%
-273.4%
Q3 24
-10795.9%
19.4%
Q2 24
-2969.3%
Q1 24
-4300.0%
EPS (diluted)
CBUS
CBUS
ENSC
ENSC
Q4 25
$-0.39
$-0.51
Q3 25
$-0.44
$-1.29
Q2 25
$-0.61
$-0.79
Q1 25
$-1.34
$-1.39
Q4 24
$-0.94
$-0.89
Q3 24
$-7.63
$1.00
Q2 24
$-1.14
Q1 24
$-1.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CBUS
CBUS
ENSC
ENSC
Cash + ST InvestmentsLiquidity on hand
$9.9M
$4.3M
Total DebtLower is stronger
$528.0K
Stockholders' EquityBook value
$21.8M
$3.2M
Total Assets
$305.0M
$7.5M
Debt / EquityLower = less leverage
0.02×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CBUS
CBUS
ENSC
ENSC
Q4 25
$9.9M
$4.3M
Q3 25
$23.9M
$1.7M
Q2 25
$36.5M
$2.2M
Q1 25
$23.6M
$3.1M
Q4 24
$14.4M
$3.5M
Q3 24
$28.8M
$4.2M
Q2 24
$30.0M
Q1 24
$24.5M
Total Debt
CBUS
CBUS
ENSC
ENSC
Q4 25
$528.0K
Q3 25
Q2 25
Q1 25
Q4 24
$662.0K
Q3 24
Q2 24
Q1 24
Stockholders' Equity
CBUS
CBUS
ENSC
ENSC
Q4 25
$21.8M
$3.2M
Q3 25
$50.4M
$1.2M
Q2 25
$72.1M
$3.4M
Q1 25
$70.3M
$3.0M
Q4 24
$92.2M
$3.7M
Q3 24
$108.1M
$6.9M
Q2 24
$270.5M
Q1 24
$278.2M
Total Assets
CBUS
CBUS
ENSC
ENSC
Q4 25
$305.0M
$7.5M
Q3 25
$330.2M
$3.2M
Q2 25
$346.2M
$5.6M
Q1 25
$335.0M
$4.6M
Q4 24
$350.1M
$5.6M
Q3 24
$367.9M
$9.4M
Q2 24
$553.4M
Q1 24
$533.0M
Debt / Equity
CBUS
CBUS
ENSC
ENSC
Q4 25
0.02×
Q3 25
Q2 25
Q1 25
Q4 24
0.01×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CBUS
CBUS
ENSC
ENSC
Operating Cash FlowLast quarter
$-13.4M
$-1.5M
Free Cash FlowOCF − Capex
$-13.5M
FCF MarginFCF / Revenue
-1277.8%
Capex IntensityCapex / Revenue
8.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-51.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CBUS
CBUS
ENSC
ENSC
Q4 25
$-13.4M
$-1.5M
Q3 25
$-11.7M
$-1.9M
Q2 25
$-13.6M
$-2.7M
Q1 25
$-11.8M
$-1.7M
Q4 24
$-14.0M
$-764.1K
Q3 24
$-13.5M
$-1.0M
Q2 24
$-17.0M
Q1 24
$-13.5M
Free Cash Flow
CBUS
CBUS
ENSC
ENSC
Q4 25
$-13.5M
Q3 25
$-11.8M
Q2 25
$-13.7M
Q1 25
$-12.1M
Q4 24
$-14.1M
Q3 24
$-13.9M
Q2 24
$-17.2M
Q1 24
$-13.7M
FCF Margin
CBUS
CBUS
ENSC
ENSC
Q4 25
-1277.8%
Q3 25
-1926.5%
Q2 25
-1468.1%
Q1 25
-1172.0%
Q4 24
-1159.3%
Q3 24
-832.3%
Q2 24
-2054.5%
Q1 24
-2515.2%
Capex Intensity
CBUS
CBUS
ENSC
ENSC
Q4 25
8.1%
Q3 25
17.6%
Q2 25
10.0%
Q1 25
28.1%
Q4 24
4.6%
Q3 24
21.3%
Q2 24
20.2%
Q1 24
41.8%
Cash Conversion
CBUS
CBUS
ENSC
ENSC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-1.54×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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