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Side-by-side financial comparison of Comstock Holding Companies, Inc. (CHCI) and Avidity Biosciences, Inc. (RNA). Click either name above to swap in a different company.

Comstock Holding Companies, Inc. is the larger business by last-quarter revenue ($23.9M vs $12.5M, roughly 1.9× Avidity Biosciences, Inc.). Comstock Holding Companies, Inc. runs the higher net margin — 56.3% vs -1398.3%, a 1454.6% gap on every dollar of revenue. On growth, Avidity Biosciences, Inc. posted the faster year-over-year revenue change (434.0% vs 41.5%). Over the past eight quarters, Avidity Biosciences, Inc.'s revenue compounded faster (138.5% CAGR vs 50.0%).

The Comstock Lode is a lode of silver ore located under the eastern slope of Mount Davidson, a peak in the Virginia Range in Virginia City, Nevada, which was the first major discovery of silver ore in the United States and named after Canadian miner Henry Comstock.

Eli Lilly and Company, doing business as Lilly, is an American multinational pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by Eli Lilly, a pharmaceutical chemist and Union army veteran during the American Civil War for whom the company was later named.

CHCI vs RNA — Head-to-Head

Bigger by revenue
CHCI
CHCI
1.9× larger
CHCI
$23.9M
$12.5M
RNA
Growing faster (revenue YoY)
RNA
RNA
+392.5% gap
RNA
434.0%
41.5%
CHCI
Higher net margin
CHCI
CHCI
1454.6% more per $
CHCI
56.3%
-1398.3%
RNA
Faster 2-yr revenue CAGR
RNA
RNA
Annualised
RNA
138.5%
50.0%
CHCI

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
CHCI
CHCI
RNA
RNA
Revenue
$23.9M
$12.5M
Net Profit
$13.5M
$-174.4M
Gross Margin
35.5%
Operating Margin
32.4%
-1513.5%
Net Margin
56.3%
-1398.3%
Revenue YoY
41.5%
434.0%
Net Profit YoY
30.5%
-117.0%
EPS (diluted)
$-1.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CHCI
CHCI
RNA
RNA
Q4 25
$23.9M
Q3 25
$13.3M
$12.5M
Q2 25
$13.0M
$3.8M
Q1 25
$12.6M
$1.6M
Q4 24
$16.9M
$3.0M
Q3 24
$13.0M
$2.3M
Q2 24
$10.8M
$2.0M
Q1 24
$10.6M
$3.5M
Net Profit
CHCI
CHCI
RNA
RNA
Q4 25
$13.5M
Q3 25
$541.0K
$-174.4M
Q2 25
$1.4M
$-157.3M
Q1 25
$1.6M
$-115.8M
Q4 24
$10.3M
$-102.3M
Q3 24
$2.4M
$-80.4M
Q2 24
$946.0K
$-70.8M
Q1 24
$910.0K
$-68.9M
Gross Margin
CHCI
CHCI
RNA
RNA
Q4 25
35.5%
Q3 25
11.0%
Q2 25
19.0%
Q1 25
18.6%
Q4 24
33.4%
Q3 24
26.3%
Q2 24
17.2%
Q1 24
16.5%
Operating Margin
CHCI
CHCI
RNA
RNA
Q4 25
32.4%
Q3 25
5.0%
-1513.5%
Q2 25
13.7%
-4448.7%
Q1 25
13.7%
-8360.9%
Q4 24
30.1%
-4069.6%
Q3 24
21.8%
-4200.9%
Q2 24
11.4%
-4040.4%
Q1 24
10.8%
-2178.6%
Net Margin
CHCI
CHCI
RNA
RNA
Q4 25
56.3%
Q3 25
4.1%
-1398.3%
Q2 25
11.1%
-4089.3%
Q1 25
12.6%
-7360.0%
Q4 24
61.1%
-3439.5%
Q3 24
18.3%
-3441.7%
Q2 24
8.8%
-3461.8%
Q1 24
8.6%
-1943.4%
EPS (diluted)
CHCI
CHCI
RNA
RNA
Q4 25
Q3 25
$-1.27
Q2 25
$-1.21
Q1 25
$-0.90
Q4 24
$-0.80
Q3 24
$-0.65
Q2 24
$-0.65
Q1 24
$0.09
$-0.79

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CHCI
CHCI
RNA
RNA
Cash + ST InvestmentsLiquidity on hand
$31.3M
$350.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$70.0M
$1.9B
Total Assets
$85.0M
$2.1B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CHCI
CHCI
RNA
RNA
Q4 25
$31.3M
Q3 25
$26.2M
$350.2M
Q2 25
$30.5M
$243.9M
Q1 25
$28.3M
$254.2M
Q4 24
$28.8M
$219.9M
Q3 24
$21.1M
$370.2M
Q2 24
$17.4M
$575.8M
Q1 24
$16.2M
$471.4M
Stockholders' Equity
CHCI
CHCI
RNA
RNA
Q4 25
$70.0M
Q3 25
$56.3M
$1.9B
Q2 25
$55.5M
$1.2B
Q1 25
$53.7M
$1.3B
Q4 24
$52.4M
$1.4B
Q3 24
$41.7M
$1.5B
Q2 24
$39.2M
$1.2B
Q1 24
$37.9M
$830.9M
Total Assets
CHCI
CHCI
RNA
RNA
Q4 25
$85.0M
Q3 25
$67.6M
$2.1B
Q2 25
$65.2M
$1.4B
Q1 25
$62.8M
$1.5B
Q4 24
$64.9M
$1.6B
Q3 24
$52.2M
$1.6B
Q2 24
$48.6M
$1.3B
Q1 24
$46.8M
$951.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CHCI
CHCI
RNA
RNA
Operating Cash FlowLast quarter
$4.8M
$-156.2M
Free Cash FlowOCF − Capex
$-156.9M
FCF MarginFCF / Revenue
-1257.6%
Capex IntensityCapex / Revenue
5.7%
Cash ConversionOCF / Net Profit
0.36×
TTM Free Cash FlowTrailing 4 quarters
$-592.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CHCI
CHCI
RNA
RNA
Q4 25
$4.8M
Q3 25
$-3.2M
$-156.2M
Q2 25
$2.2M
$-199.7M
Q1 25
$582.0K
$-124.8M
Q4 24
$10.7M
$-99.9M
Q3 24
$3.9M
$-65.6M
Q2 24
$1.3M
$-65.0M
Q1 24
$-2.2M
$-70.4M
Free Cash Flow
CHCI
CHCI
RNA
RNA
Q4 25
Q3 25
$-156.9M
Q2 25
$-203.0M
Q1 25
$-128.6M
Q4 24
$-103.8M
Q3 24
$-67.3M
Q2 24
$-65.5M
Q1 24
$-71.3M
FCF Margin
CHCI
CHCI
RNA
RNA
Q4 25
Q3 25
-1257.6%
Q2 25
-5277.1%
Q1 25
-8174.3%
Q4 24
-3491.0%
Q3 24
-2881.8%
Q2 24
-3204.6%
Q1 24
-2012.3%
Capex Intensity
CHCI
CHCI
RNA
RNA
Q4 25
Q3 25
5.7%
Q2 25
86.9%
Q1 25
238.6%
Q4 24
131.7%
Q3 24
72.9%
Q2 24
26.0%
Q1 24
25.8%
Cash Conversion
CHCI
CHCI
RNA
RNA
Q4 25
0.36×
Q3 25
-5.96×
Q2 25
1.51×
Q1 25
0.37×
Q4 24
1.03×
Q3 24
1.63×
Q2 24
1.35×
Q1 24
-2.46×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CHCI
CHCI

Related Party$22.1M92%
Nonrelated Party$1.9M8%

RNA
RNA

Segment breakdown not available.

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