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Side-by-side financial comparison of Charles River Laboratories (CRL) and SAIA INC (SAIA). Click either name above to swap in a different company.

Charles River Laboratories is the larger business by last-quarter revenue ($994.2M vs $790.0M, roughly 1.3× SAIA INC). SAIA INC runs the higher net margin — 6.0% vs -27.8%, a 33.8% gap on every dollar of revenue. On growth, SAIA INC posted the faster year-over-year revenue change (0.1% vs -0.8%). Charles River Laboratories produced more free cash flow last quarter ($58.6M vs $37.5M). Over the past eight quarters, SAIA INC's revenue compounded faster (2.3% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

Saia is an American less than truckload (LTL) trucking company that originated in Houma, Louisiana, in 1924. With original operation occurring in Louisiana and Texas for the first fifty years, expansion came after 1980 when coverage began reaching into more states in the South. Further expansion happened through mergers with other companies, which allowed Saia to provide service for thirty six states. Saia ranks in the top ten of LTL carriers in the United States, with revenues of over $1.8 b...

CRL vs SAIA — Head-to-Head

Bigger by revenue
CRL
CRL
1.3× larger
CRL
$994.2M
$790.0M
SAIA
Growing faster (revenue YoY)
SAIA
SAIA
+1.0% gap
SAIA
0.1%
-0.8%
CRL
Higher net margin
SAIA
SAIA
33.8% more per $
SAIA
6.0%
-27.8%
CRL
More free cash flow
CRL
CRL
$21.1M more FCF
CRL
$58.6M
$37.5M
SAIA
Faster 2-yr revenue CAGR
SAIA
SAIA
Annualised
SAIA
2.3%
-0.9%
CRL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CRL
CRL
SAIA
SAIA
Revenue
$994.2M
$790.0M
Net Profit
$-276.6M
$47.5M
Gross Margin
Operating Margin
-28.5%
8.1%
Net Margin
-27.8%
6.0%
Revenue YoY
-0.8%
0.1%
Net Profit YoY
-28.9%
-37.6%
EPS (diluted)
$-5.57
$1.77

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRL
CRL
SAIA
SAIA
Q4 25
$994.2M
$790.0M
Q3 25
$1.0B
$839.6M
Q2 25
$1.0B
$817.1M
Q1 25
$984.2M
$787.6M
Q4 24
$1.0B
$789.0M
Q3 24
$1.0B
$842.1M
Q2 24
$1.0B
$823.2M
Q1 24
$1.0B
$754.8M
Net Profit
CRL
CRL
SAIA
SAIA
Q4 25
$-276.6M
$47.5M
Q3 25
$54.4M
$86.3M
Q2 25
$52.3M
$71.4M
Q1 25
$25.5M
$49.8M
Q4 24
$-214.5M
$76.1M
Q3 24
$69.7M
$92.7M
Q2 24
$94.1M
$102.5M
Q1 24
$73.0M
$90.7M
Gross Margin
CRL
CRL
SAIA
SAIA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
34.6%
Q2 24
34.5%
Q1 24
34.1%
Operating Margin
CRL
CRL
SAIA
SAIA
Q4 25
-28.5%
8.1%
Q3 25
13.3%
14.1%
Q2 25
9.7%
12.2%
Q1 25
7.6%
8.9%
Q4 24
-16.7%
12.9%
Q3 24
11.6%
14.9%
Q2 24
14.8%
16.7%
Q1 24
12.5%
15.6%
Net Margin
CRL
CRL
SAIA
SAIA
Q4 25
-27.8%
6.0%
Q3 25
5.4%
10.3%
Q2 25
5.1%
8.7%
Q1 25
2.6%
6.3%
Q4 24
-21.4%
9.6%
Q3 24
6.9%
11.0%
Q2 24
9.2%
12.5%
Q1 24
7.2%
12.0%
EPS (diluted)
CRL
CRL
SAIA
SAIA
Q4 25
$-5.57
$1.77
Q3 25
$1.10
$3.22
Q2 25
$1.06
$2.67
Q1 25
$0.50
$1.86
Q4 24
$-4.17
$2.84
Q3 24
$1.33
$3.46
Q2 24
$1.74
$3.83
Q1 24
$1.30
$3.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRL
CRL
SAIA
SAIA
Cash + ST InvestmentsLiquidity on hand
$213.8M
$19.7M
Total DebtLower is stronger
$2.1B
$163.0M
Stockholders' EquityBook value
$3.2B
$2.6B
Total Assets
$7.1B
$3.5B
Debt / EquityLower = less leverage
0.68×
0.06×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRL
CRL
SAIA
SAIA
Q4 25
$213.8M
$19.7M
Q3 25
$207.1M
$35.5M
Q2 25
$182.8M
$18.8M
Q1 25
$229.4M
$16.5M
Q4 24
$194.6M
$19.5M
Q3 24
$210.2M
$14.4M
Q2 24
$179.2M
$11.2M
Q1 24
$327.0M
$12.3M
Total Debt
CRL
CRL
SAIA
SAIA
Q4 25
$2.1B
$163.0M
Q3 25
$2.2B
$218.0M
Q2 25
$2.3B
$307.1M
Q1 25
$2.5B
$291.8M
Q4 24
$2.2B
$195.0M
Q3 24
$2.3B
$184.2M
Q2 24
$2.4B
$169.1M
Q1 24
$2.7B
$76.6M
Stockholders' Equity
CRL
CRL
SAIA
SAIA
Q4 25
$3.2B
$2.6B
Q3 25
$3.4B
$2.5B
Q2 25
$3.4B
$2.4B
Q1 25
$3.2B
$2.4B
Q4 24
$3.5B
$2.3B
Q3 24
$3.8B
$2.2B
Q2 24
$3.7B
$2.1B
Q1 24
$3.6B
$2.0B
Total Assets
CRL
CRL
SAIA
SAIA
Q4 25
$7.1B
$3.5B
Q3 25
$7.5B
$3.5B
Q2 25
$7.6B
$3.5B
Q1 25
$7.6B
$3.4B
Q4 24
$7.5B
$3.2B
Q3 24
$8.0B
$3.1B
Q2 24
$7.9B
$3.0B
Q1 24
$8.2B
$2.8B
Debt / Equity
CRL
CRL
SAIA
SAIA
Q4 25
0.68×
0.06×
Q3 25
0.64×
0.09×
Q2 25
0.70×
0.13×
Q1 25
0.79×
0.12×
Q4 24
0.65×
0.08×
Q3 24
0.62×
0.08×
Q2 24
0.65×
0.08×
Q1 24
0.73×
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRL
CRL
SAIA
SAIA
Operating Cash FlowLast quarter
$147.5M
$137.3M
Free Cash FlowOCF − Capex
$58.6M
$37.5M
FCF MarginFCF / Revenue
5.9%
4.7%
Capex IntensityCapex / Revenue
8.9%
12.6%
Cash ConversionOCF / Net Profit
2.89×
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$27.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRL
CRL
SAIA
SAIA
Q4 25
$147.5M
$137.3M
Q3 25
$213.8M
$177.8M
Q2 25
$204.6M
$170.7M
Q1 25
$171.7M
$109.1M
Q4 24
$159.4M
$164.7M
Q3 24
$251.8M
$181.7M
Q2 24
$193.5M
$130.8M
Q1 24
$129.9M
$106.5M
Free Cash Flow
CRL
CRL
SAIA
SAIA
Q4 25
$58.6M
$37.5M
Q3 25
$178.2M
$87.6M
Q2 25
$169.3M
$-3.9M
Q1 25
$112.4M
$-93.8M
Q4 24
$83.7M
$-3.5M
Q3 24
$213.1M
$-11.7M
Q2 24
$154.0M
$-94.0M
Q1 24
$50.7M
$-350.7M
FCF Margin
CRL
CRL
SAIA
SAIA
Q4 25
5.9%
4.7%
Q3 25
17.7%
10.4%
Q2 25
16.4%
-0.5%
Q1 25
11.4%
-11.9%
Q4 24
8.4%
-0.4%
Q3 24
21.1%
-1.4%
Q2 24
15.0%
-11.4%
Q1 24
5.0%
-46.5%
Capex Intensity
CRL
CRL
SAIA
SAIA
Q4 25
8.9%
12.6%
Q3 25
3.5%
10.8%
Q2 25
3.4%
21.4%
Q1 25
6.0%
25.8%
Q4 24
7.5%
21.3%
Q3 24
3.8%
23.0%
Q2 24
3.8%
27.3%
Q1 24
7.8%
60.6%
Cash Conversion
CRL
CRL
SAIA
SAIA
Q4 25
2.89×
Q3 25
3.93×
2.06×
Q2 25
3.91×
2.39×
Q1 25
6.74×
2.19×
Q4 24
2.16×
Q3 24
3.61×
1.96×
Q2 24
2.06×
1.28×
Q1 24
1.78×
1.17×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

SAIA
SAIA

Segment breakdown not available.

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