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Side-by-side financial comparison of CASTLE BIOSCIENCES INC (CSTL) and JBG SMITH Properties (JBGS). Click either name above to swap in a different company.

JBG SMITH Properties is the larger business by last-quarter revenue ($127.6M vs $87.0M, roughly 1.5× CASTLE BIOSCIENCES INC). On growth, CASTLE BIOSCIENCES INC posted the faster year-over-year revenue change (0.8% vs -2.5%). Over the past eight quarters, CASTLE BIOSCIENCES INC's revenue compounded faster (9.2% CAGR vs -6.3%).

Castle Biosciences Inc. is a commercial-stage diagnostic firm that develops and markets proprietary, clinically actionable tests for dermatological conditions such as melanoma and other skin cancers, plus rare diseases. It operates mainly in the U.S. healthcare market, focusing on segments with high unmet need for more accurate diagnostics to guide treatment choices.

JBG SMITH Properties is a publicly traded real estate investment trust based in Bethesda, Maryland.

CSTL vs JBGS — Head-to-Head

Bigger by revenue
JBGS
JBGS
1.5× larger
JBGS
$127.6M
$87.0M
CSTL
Growing faster (revenue YoY)
CSTL
CSTL
+3.3% gap
CSTL
0.8%
-2.5%
JBGS
Faster 2-yr revenue CAGR
CSTL
CSTL
Annualised
CSTL
9.2%
-6.3%
JBGS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CSTL
CSTL
JBGS
JBGS
Revenue
$87.0M
$127.6M
Net Profit
$-45.5M
Gross Margin
79.0%
Operating Margin
-4.4%
-47.5%
Net Margin
-35.7%
Revenue YoY
0.8%
-2.5%
Net Profit YoY
24.0%
EPS (diluted)
$-0.06
$-0.76

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CSTL
CSTL
JBGS
JBGS
Q4 25
$87.0M
$127.6M
Q3 25
$83.0M
$123.9M
Q2 25
$86.2M
$126.5M
Q1 25
$88.0M
$120.7M
Q4 24
$86.3M
$130.8M
Q3 24
$85.8M
$136.0M
Q2 24
$87.0M
$135.3M
Q1 24
$73.0M
$145.2M
Net Profit
CSTL
CSTL
JBGS
JBGS
Q4 25
$-45.5M
Q3 25
$-501.0K
$-28.6M
Q2 25
$4.5M
$-19.2M
Q1 25
$-25.8M
$-45.7M
Q4 24
$-59.9M
Q3 24
$2.3M
$-27.0M
Q2 24
$8.9M
$-24.4M
Q1 24
$-2.5M
$-32.3M
Gross Margin
CSTL
CSTL
JBGS
JBGS
Q4 25
79.0%
Q3 25
77.5%
Q2 25
79.5%
Q1 25
81.4%
Q4 24
81.3%
Q3 24
81.8%
Q2 24
83.3%
Q1 24
81.0%
Operating Margin
CSTL
CSTL
JBGS
JBGS
Q4 25
-4.4%
-47.5%
Q3 25
-8.2%
-27.5%
Q2 25
-4.9%
-18.4%
Q1 25
-31.7%
-44.7%
Q4 24
4.7%
-53.6%
Q3 24
5.9%
-22.4%
Q2 24
5.8%
-24.3%
Q1 24
-7.5%
-30.1%
Net Margin
CSTL
CSTL
JBGS
JBGS
Q4 25
-35.7%
Q3 25
-0.6%
-23.1%
Q2 25
5.2%
-15.2%
Q1 25
-29.4%
-37.9%
Q4 24
-45.8%
Q3 24
2.6%
-19.8%
Q2 24
10.3%
-18.0%
Q1 24
-3.5%
-22.2%
EPS (diluted)
CSTL
CSTL
JBGS
JBGS
Q4 25
$-0.06
$-0.76
Q3 25
$-0.02
$-0.48
Q2 25
$0.15
$-0.29
Q1 25
$-0.90
$-0.56
Q4 24
$0.32
$-0.70
Q3 24
$0.08
$-0.32
Q2 24
$0.31
$-0.27
Q1 24
$-0.09
$-0.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CSTL
CSTL
JBGS
JBGS
Cash + ST InvestmentsLiquidity on hand
$299.5M
$75.3M
Total DebtLower is stronger
$10.1M
Stockholders' EquityBook value
$470.9M
$1.2B
Total Assets
$578.6M
$4.4B
Debt / EquityLower = less leverage
0.02×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CSTL
CSTL
JBGS
JBGS
Q4 25
$299.5M
$75.3M
Q3 25
$287.5M
$64.4M
Q2 25
$275.9M
$61.4M
Q1 25
$275.2M
$81.3M
Q4 24
$293.1M
$145.8M
Q3 24
$95.0M
$137.0M
Q2 24
$85.6M
$163.5M
Q1 24
$82.9M
$220.5M
Total Debt
CSTL
CSTL
JBGS
JBGS
Q4 25
$10.1M
Q3 25
$10.0M
Q2 25
$10.0M
Q1 25
$10.0M
Q4 24
$10.0M
Q3 24
$10.0M
Q2 24
$10.0M
Q1 24
$10.0M
Stockholders' Equity
CSTL
CSTL
JBGS
JBGS
Q4 25
$470.9M
$1.2B
Q3 25
$467.0M
$1.2B
Q2 25
$455.4M
$1.3B
Q1 25
$440.3M
$1.6B
Q4 24
$455.8M
$1.8B
Q3 24
$441.1M
$1.9B
Q2 24
$423.9M
$2.0B
Q1 24
$402.5M
$2.1B
Total Assets
CSTL
CSTL
JBGS
JBGS
Q4 25
$578.6M
$4.4B
Q3 25
$562.8M
$4.4B
Q2 25
$544.7M
$4.5B
Q1 25
$501.7M
$4.7B
Q4 24
$531.2M
$5.0B
Q3 24
$514.6M
$5.2B
Q2 24
$487.3M
$5.3B
Q1 24
$458.5M
$5.4B
Debt / Equity
CSTL
CSTL
JBGS
JBGS
Q4 25
0.02×
Q3 25
0.02×
Q2 25
0.02×
Q1 25
0.02×
Q4 24
0.02×
Q3 24
0.02×
Q2 24
0.02×
Q1 24
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CSTL
CSTL
JBGS
JBGS
Operating Cash FlowLast quarter
$26.9M
$73.3M
Free Cash FlowOCF − Capex
$19.7M
FCF MarginFCF / Revenue
22.7%
Capex IntensityCapex / Revenue
8.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$28.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CSTL
CSTL
JBGS
JBGS
Q4 25
$26.9M
$73.3M
Q3 25
$22.6M
$8.9M
Q2 25
$20.8M
$18.8M
Q1 25
$-6.0M
$12.9M
Q4 24
$24.4M
$129.4M
Q3 24
$23.3M
$26.4M
Q2 24
$24.0M
$23.8M
Q1 24
$-6.8M
$37.0M
Free Cash Flow
CSTL
CSTL
JBGS
JBGS
Q4 25
$19.7M
Q3 25
$7.8M
Q2 25
$11.6M
Q1 25
$-10.8M
Q4 24
$16.8M
Q3 24
$17.0M
Q2 24
$18.8M
Q1 24
$-16.0M
FCF Margin
CSTL
CSTL
JBGS
JBGS
Q4 25
22.7%
Q3 25
9.4%
Q2 25
13.4%
Q1 25
-12.2%
Q4 24
19.5%
Q3 24
19.8%
Q2 24
21.6%
Q1 24
-21.9%
Capex Intensity
CSTL
CSTL
JBGS
JBGS
Q4 25
8.3%
Q3 25
17.9%
Q2 25
10.7%
Q1 25
5.4%
Q4 24
8.8%
Q3 24
7.4%
Q2 24
6.0%
Q1 24
12.5%
Cash Conversion
CSTL
CSTL
JBGS
JBGS
Q4 25
Q3 25
Q2 25
4.60×
Q1 25
Q4 24
Q3 24
10.29×
Q2 24
2.69×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CSTL
CSTL

Dermatologic$48.6M56%
Non Dermatologic$38.4M44%

JBGS
JBGS

Segment breakdown not available.

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