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Side-by-side financial comparison of Cue Biopharma, Inc. (CUE) and SOLESENCE, INC. (SLSN). Click either name above to swap in a different company.
Cue Biopharma, Inc. is the larger business by last-quarter revenue ($21.9M vs $12.5M, roughly 1.8× SOLESENCE, INC.). Cue Biopharma, Inc. runs the higher net margin — 7.2% vs 1.3%, a 5.9% gap on every dollar of revenue. On growth, Cue Biopharma, Inc. posted the faster year-over-year revenue change (1292.3% vs -0.7%). Over the past eight quarters, Cue Biopharma, Inc.'s revenue compounded faster (257.5% CAGR vs 12.5%).
Cue Biopharma is a clinical-stage biotechnology company focused on developing novel targeted immunotherapies for cancer, autoimmune disorders, and inflammatory diseases. Its proprietary platform enables precise T-cell activity modulation, with core operations in North America and global pharma partnerships to advance lead product candidates through clinical trials.
CUE vs SLSN — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $21.9M | $12.5M |
| Net Profit | $1.6M | $163.0K |
| Gross Margin | — | 27.5% |
| Operating Margin | 9.0% | 1.5% |
| Net Margin | 7.2% | 1.3% |
| Revenue YoY | 1292.3% | -0.7% |
| Net Profit YoY | 116.7% | 129.2% |
| EPS (diluted) | $0.05 | $0.00 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $21.9M | $12.5M | ||
| Q3 25 | $2.1M | $14.6M | ||
| Q2 25 | $3.0M | $20.4M | ||
| Q1 25 | $421.0K | $14.6M | ||
| Q4 24 | $1.6M | $12.6M | ||
| Q3 24 | $3.3M | $16.9M | ||
| Q2 24 | $2.7M | $13.0M | ||
| Q1 24 | $1.7M | $9.9M |
| Q4 25 | $1.6M | $163.0K | ||
| Q3 25 | $-7.4M | $-1.1M | ||
| Q2 25 | $-8.5M | $2.7M | ||
| Q1 25 | $-12.3M | $80.0K | ||
| Q4 24 | — | $-559.0K | ||
| Q3 24 | $-8.7M | $3.0M | ||
| Q2 24 | $-10.2M | $856.0K | ||
| Q1 24 | $-12.3M | $893.0K |
| Q4 25 | — | 27.5% | ||
| Q3 25 | — | 23.1% | ||
| Q2 25 | — | 28.9% | ||
| Q1 25 | — | 23.1% | ||
| Q4 24 | — | 22.0% | ||
| Q3 24 | — | 36.2% | ||
| Q2 24 | — | 28.7% | ||
| Q1 24 | — | 36.3% |
| Q4 25 | 9.0% | 1.5% | ||
| Q3 25 | -353.4% | -5.4% | ||
| Q2 25 | -292.3% | 9.4% | ||
| Q1 25 | -2921.4% | 1.8% | ||
| Q4 24 | — | -1.8% | ||
| Q3 24 | -264.2% | 19.0% | ||
| Q2 24 | -390.6% | 8.0% | ||
| Q1 24 | -737.8% | 11.3% |
| Q4 25 | 7.2% | 1.3% | ||
| Q3 25 | -346.6% | -7.7% | ||
| Q2 25 | -287.1% | 13.1% | ||
| Q1 25 | -2911.4% | 0.5% | ||
| Q4 24 | — | -4.4% | ||
| Q3 24 | -259.6% | 18.1% | ||
| Q2 24 | -382.7% | 6.6% | ||
| Q1 24 | -719.1% | 9.0% |
| Q4 25 | $0.05 | $0.00 | ||
| Q3 25 | $-0.07 | $-0.02 | ||
| Q2 25 | $-0.09 | $0.04 | ||
| Q1 25 | $-0.17 | $0.00 | ||
| Q4 24 | — | $0.00 | ||
| Q3 24 | $-0.17 | $0.04 | ||
| Q2 24 | $-0.20 | $0.01 | ||
| Q1 24 | $-0.25 | $0.02 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $27.1M | $1.3M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $26.4M | $17.6M |
| Total Assets | $42.2M | $50.1M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $27.1M | $1.3M | ||
| Q3 25 | $11.7M | $429.0K | ||
| Q2 25 | $27.5M | $4.1M | ||
| Q1 25 | $13.1M | $1.8M | ||
| Q4 24 | $22.5M | $1.4M | ||
| Q3 24 | $32.4M | $2.9M | ||
| Q2 24 | $30.0M | $2.4M | ||
| Q1 24 | $41.0M | $2.0M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | $1.0M | — | ||
| Q2 24 | $2.0M | — | ||
| Q1 24 | $3.0M | — |
| Q4 25 | $26.4M | $17.6M | ||
| Q3 25 | $13.2M | $17.2M | ||
| Q2 25 | $18.2M | $18.2M | ||
| Q1 25 | $6.6M | $15.2M | ||
| Q4 24 | $17.5M | $14.9M | ||
| Q3 24 | $25.4M | $15.2M | ||
| Q2 24 | $21.6M | $11.9M | ||
| Q1 24 | $30.0M | $5.0M |
| Q4 25 | $42.2M | $50.1M | ||
| Q3 25 | $31.6M | $54.0M | ||
| Q2 25 | $40.7M | $60.0M | ||
| Q1 25 | $22.3M | $57.0M | ||
| Q4 24 | $32.2M | $50.0M | ||
| Q3 24 | $44.8M | $48.0M | ||
| Q2 24 | $42.3M | $40.8M | ||
| Q1 24 | $54.0M | $38.5M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 0.04× | — | ||
| Q2 24 | 0.09× | — | ||
| Q1 24 | 0.10× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-1.1M | $1.8M |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | -0.68× | 11.16× |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-1.1M | $1.8M | ||
| Q3 25 | $-9.0M | $-2.5M | ||
| Q2 25 | $-3.4M | $-654.0K | ||
| Q1 25 | $-8.2M | $-7.2M | ||
| Q4 24 | $-36.3M | $2.2M | ||
| Q3 24 | $-7.5M | $4.2M | ||
| Q2 24 | $-10.0M | $-565.0K | ||
| Q1 24 | $-9.8M | $-3.9M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | $-3.4M | — | ||
| Q1 25 | $-8.3M | — | ||
| Q4 24 | $-36.4M | $-404.0K | ||
| Q3 24 | $-7.5M | $2.8M | ||
| Q2 24 | $-10.0M | $-1.0M | ||
| Q1 24 | $-9.8M | $-3.9M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | -116.5% | — | ||
| Q1 25 | -1976.7% | — | ||
| Q4 24 | -2309.3% | -3.2% | ||
| Q3 24 | -225.7% | 16.6% | ||
| Q2 24 | -376.2% | -8.0% | ||
| Q1 24 | -573.0% | -39.9% |
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.9% | — | ||
| Q1 25 | 35.6% | — | ||
| Q4 24 | 4.2% | 20.6% | ||
| Q3 24 | 0.0% | 8.3% | ||
| Q2 24 | 0.4% | 3.7% | ||
| Q1 24 | 3.2% | 0.9% |
| Q4 25 | -0.68× | 11.16× | ||
| Q3 25 | — | — | ||
| Q2 25 | — | -0.25× | ||
| Q1 25 | — | -90.26× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 1.38× | ||
| Q2 24 | — | -0.66× | ||
| Q1 24 | — | -4.32× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CUE
| Immuno Scape Collaboration And License Agreement | $9.5M | 43% |
| BI Collaboration And License Agreement | $8.1M | 37% |
| Other | $4.3M | 20% |
SLSN
Segment breakdown not available.
