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Side-by-side financial comparison of Devon Energy (DVN) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Devon Energy is the larger business by last-quarter revenue ($3.8B vs $3.0B, roughly 1.3× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 3.2%, a 31.4% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs -14.5%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs -1.1%).

Devon Energy Corporation is an American company engaged in hydrocarbon exploration. It is organized in Delaware with operational headquarters in the 50-story Devon Energy Center in Oklahoma City, Oklahoma. Its operations are in the Delaware Basin, Eagle Ford Group, and the Rocky Mountains.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

DVN vs VRTX — Head-to-Head

Bigger by revenue
DVN
DVN
1.3× larger
DVN
$3.8B
$3.0B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+22.3% gap
VRTX
7.8%
-14.5%
DVN
Higher net margin
VRTX
VRTX
31.4% more per $
VRTX
34.5%
3.2%
DVN
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
-1.1%
DVN

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
DVN
DVN
VRTX
VRTX
Revenue
$3.8B
$3.0B
Net Profit
$120.0M
$1.0B
Gross Margin
86.8%
Operating Margin
38.1%
Net Margin
3.2%
34.5%
Revenue YoY
-14.5%
7.8%
Net Profit YoY
-76.4%
59.6%
EPS (diluted)
$0.19
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DVN
DVN
VRTX
VRTX
Q1 26
$3.8B
$3.0B
Q4 25
$3.9B
$3.2B
Q3 25
$4.3B
$3.1B
Q2 25
$4.0B
$3.0B
Q1 25
$4.5B
$2.8B
Q4 24
$4.5B
$2.9B
Q3 24
$3.8B
$2.8B
Q2 24
$3.9B
$2.6B
Net Profit
DVN
DVN
VRTX
VRTX
Q1 26
$120.0M
$1.0B
Q4 25
$562.0M
$1.2B
Q3 25
$687.0M
$1.1B
Q2 25
$899.0M
$1.0B
Q1 25
$494.0M
$646.3M
Q4 24
$639.0M
$913.0M
Q3 24
$812.0M
$1.0B
Q2 24
$844.0M
$-3.6B
Gross Margin
DVN
DVN
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
DVN
DVN
VRTX
VRTX
Q1 26
38.1%
Q4 25
19.0%
37.8%
Q3 25
21.5%
38.6%
Q2 25
28.7%
38.8%
Q1 25
14.2%
22.7%
Q4 24
18.7%
35.2%
Q3 24
28.0%
40.3%
Q2 24
26.7%
-132.9%
Net Margin
DVN
DVN
VRTX
VRTX
Q1 26
3.2%
34.5%
Q4 25
14.3%
37.3%
Q3 25
16.2%
35.2%
Q2 25
22.2%
34.8%
Q1 25
10.9%
23.3%
Q4 24
14.2%
31.4%
Q3 24
21.4%
37.7%
Q2 24
21.7%
-135.8%
EPS (diluted)
DVN
DVN
VRTX
VRTX
Q1 26
$0.19
$4.02
Q4 25
$0.90
$4.64
Q3 25
$1.09
$4.20
Q2 25
$1.41
$3.99
Q1 25
$0.77
$2.49
Q4 24
$0.98
$3.62
Q3 24
$1.30
$4.01
Q2 24
$1.34
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DVN
DVN
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.8B
Total DebtLower is stronger
$8.4B
Stockholders' EquityBook value
$15.4B
$19.4B
Total Assets
$32.5B
$26.5B
Debt / EquityLower = less leverage
0.54×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DVN
DVN
VRTX
VRTX
Q1 26
$1.8B
Q4 25
$1.4B
$6.6B
Q3 25
$1.2B
$6.3B
Q2 25
$1.7B
$6.4B
Q1 25
$1.2B
$6.2B
Q4 24
$811.0M
$6.1B
Q3 24
$645.0M
$6.5B
Q2 24
$1.1B
$5.8B
Total Debt
DVN
DVN
VRTX
VRTX
Q1 26
$8.4B
Q4 25
$8.4B
Q3 25
$8.4B
Q2 25
$8.9B
Q1 25
$8.9B
Q4 24
$8.9B
Q3 24
$8.9B
Q2 24
$6.1B
Stockholders' Equity
DVN
DVN
VRTX
VRTX
Q1 26
$15.4B
$19.4B
Q4 25
$15.5B
$18.7B
Q3 25
$15.3B
$17.3B
Q2 25
$15.1B
$17.2B
Q1 25
$14.5B
$16.5B
Q4 24
$14.5B
$16.4B
Q3 24
$14.3B
$15.6B
Q2 24
$12.6B
$14.8B
Total Assets
DVN
DVN
VRTX
VRTX
Q1 26
$32.5B
$26.5B
Q4 25
$31.6B
$25.6B
Q3 25
$31.2B
$24.9B
Q2 25
$31.4B
$24.0B
Q1 25
$30.9B
$22.9B
Q4 24
$30.5B
$22.5B
Q3 24
$30.3B
$22.2B
Q2 24
$25.2B
$20.1B
Debt / Equity
DVN
DVN
VRTX
VRTX
Q1 26
0.54×
Q4 25
0.54×
Q3 25
0.55×
Q2 25
0.59×
Q1 25
0.61×
Q4 24
0.61×
Q3 24
0.62×
Q2 24
0.49×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DVN
DVN
VRTX
VRTX
Operating Cash FlowLast quarter
Free Cash FlowOCF − Capex
$12.0M
FCF MarginFCF / Revenue
0.3%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$2.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DVN
DVN
VRTX
VRTX
Q1 26
Q4 25
$1.5B
$498.0M
Q3 25
$1.7B
$1.2B
Q2 25
$1.5B
$1.1B
Q1 25
$1.9B
$818.9M
Q4 24
$1.7B
$584.6M
Q3 24
$1.7B
$1.4B
Q2 24
$1.5B
$-3.8B
Free Cash Flow
DVN
DVN
VRTX
VRTX
Q1 26
$12.0M
Q4 25
$702.0M
$348.6M
Q3 25
$820.0M
$1.1B
Q2 25
$589.0M
$927.4M
Q1 25
$1.0B
$778.2M
Q4 24
$738.0M
$492.0M
Q3 24
$786.0M
$1.3B
Q2 24
$587.0M
$-3.8B
FCF Margin
DVN
DVN
VRTX
VRTX
Q1 26
0.3%
Q4 25
17.8%
10.9%
Q3 25
19.3%
37.0%
Q2 25
14.6%
31.3%
Q1 25
22.2%
28.1%
Q4 24
16.4%
16.9%
Q3 24
20.7%
47.0%
Q2 24
15.1%
-144.5%
Capex Intensity
DVN
DVN
VRTX
VRTX
Q1 26
0.2%
Q4 25
21.1%
4.7%
Q3 25
20.5%
3.3%
Q2 25
23.6%
4.9%
Q1 25
20.5%
1.5%
Q4 24
20.6%
3.2%
Q3 24
23.1%
2.4%
Q2 24
24.3%
2.6%
Cash Conversion
DVN
DVN
VRTX
VRTX
Q1 26
Q4 25
2.73×
0.42×
Q3 25
2.46×
1.15×
Q2 25
1.72×
1.04×
Q1 25
3.93×
1.27×
Q4 24
2.60×
0.64×
Q3 24
2.05×
1.31×
Q2 24
1.82×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DVN
DVN

Oil, gas and NGL sales$3.0B78%
Other$646.0M17%
Oil, gas and NGL derivatives (1)$184.0M5%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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