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Side-by-side financial comparison of Ensysce Biosciences, Inc. (ENSC) and UNITED GUARDIAN INC (UG). Click either name above to swap in a different company.

UNITED GUARDIAN INC is the larger business by last-quarter revenue ($3.0M vs $1.9M, roughly 1.6× Ensysce Biosciences, Inc.). On growth, Ensysce Biosciences, Inc. posted the faster year-over-year revenue change (44.4% vs 19.6%). Over the past eight quarters, Ensysce Biosciences, Inc.'s revenue compounded faster (107.9% CAGR vs -4.6%).

Ensysce Biosciences, Inc. is a clinical-stage biotechnology firm specializing in developing innovative prodrug therapies for pain management and oncology indications. Its proprietary platform is designed to reduce opioid abuse risks while enhancing treatment efficacy, targeting global healthcare and pharmaceutical markets with a focus on unmet clinical needs.

The Guardian Life Insurance Company of America is one of the largest mutual life insurance companies in the world. Based in Manhattan, it has approximately 8,000 employees in the United States, and a network of over 3,000 financial representatives in more than 70 agencies nationwide. As of 2018, it ranks 239th on the Fortune 500 list of largest American corporations by revenue. In 2015, Guardian achieved the highest earnings in its 155-year history with $7.3 billion in capital and $1.5 billio...

ENSC vs UG — Head-to-Head

Bigger by revenue
UG
UG
1.6× larger
UG
$3.0M
$1.9M
ENSC
Growing faster (revenue YoY)
ENSC
ENSC
+24.8% gap
ENSC
44.4%
19.6%
UG
Faster 2-yr revenue CAGR
ENSC
ENSC
Annualised
ENSC
107.9%
-4.6%
UG

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ENSC
ENSC
UG
UG
Revenue
$1.9M
$3.0M
Net Profit
$-2.8M
Gross Margin
45.0%
Operating Margin
-147.8%
24.4%
Net Margin
-147.0%
Revenue YoY
44.4%
19.6%
Net Profit YoY
22.3%
EPS (diluted)
$-0.51

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ENSC
ENSC
UG
UG
Q4 25
$1.9M
$3.0M
Q3 25
$493.1K
$2.3M
Q2 25
$1.4M
$2.8M
Q1 25
$1.3M
$2.5M
Q4 24
$1.3M
$2.5M
Q3 24
$3.4M
$3.1M
Q2 24
$3.4M
Q1 24
$3.3M
Net Profit
ENSC
ENSC
UG
UG
Q4 25
$-2.8M
Q3 25
$-3.7M
$268.4K
Q2 25
$-1.7M
$626.8K
Q1 25
$-1.9M
$560.9K
Q4 24
$-3.6M
Q3 24
$661.8K
$865.5K
Q2 24
$956.2K
Q1 24
$925.4K
Gross Margin
ENSC
ENSC
UG
UG
Q4 25
45.0%
Q3 25
42.1%
Q2 25
52.8%
Q1 25
54.7%
Q4 24
51.7%
Q3 24
54.0%
Q2 24
54.0%
Q1 24
52.2%
Operating Margin
ENSC
ENSC
UG
UG
Q4 25
-147.8%
24.4%
Q3 25
-758.7%
9.5%
Q2 25
-127.6%
24.5%
Q1 25
-149.1%
24.6%
Q4 24
-274.3%
22.5%
Q3 24
18.9%
31.0%
Q2 24
32.9%
Q1 24
31.5%
Net Margin
ENSC
ENSC
UG
UG
Q4 25
-147.0%
Q3 25
-756.3%
11.9%
Q2 25
-126.4%
22.1%
Q1 25
-147.4%
22.6%
Q4 24
-273.4%
Q3 24
19.4%
28.3%
Q2 24
28.2%
Q1 24
28.4%
EPS (diluted)
ENSC
ENSC
UG
UG
Q4 25
$-0.51
Q3 25
$-1.29
Q2 25
$-0.79
Q1 25
$-1.39
Q4 24
$-0.89
Q3 24
$1.00
Q2 24
Q1 24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ENSC
ENSC
UG
UG
Cash + ST InvestmentsLiquidity on hand
$4.3M
$8.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$3.2M
$11.2M
Total Assets
$7.5M
$13.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ENSC
ENSC
UG
UG
Q4 25
$4.3M
$8.6M
Q3 25
$1.7M
$8.3M
Q2 25
$2.2M
$8.4M
Q1 25
$3.1M
$8.1M
Q4 24
$3.5M
$9.4M
Q3 24
$4.2M
$9.5M
Q2 24
$9.9M
Q1 24
$8.6M
Stockholders' Equity
ENSC
ENSC
UG
UG
Q4 25
$3.2M
$11.2M
Q3 25
$1.2M
$10.6M
Q2 25
$3.4M
$11.5M
Q1 25
$3.0M
$10.8M
Q4 24
$3.7M
$11.9M
Q3 24
$6.9M
$11.4M
Q2 24
$12.1M
Q1 24
$11.2M
Total Assets
ENSC
ENSC
UG
UG
Q4 25
$7.5M
$13.1M
Q3 25
$3.2M
$12.2M
Q2 25
$5.6M
$13.4M
Q1 25
$4.6M
$12.8M
Q4 24
$5.6M
$13.8M
Q3 24
$9.4M
$13.3M
Q2 24
$13.8M
Q1 24
$13.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ENSC
ENSC
UG
UG
Operating Cash FlowLast quarter
$-1.5M
$330.5K
Free Cash FlowOCF − Capex
$308.0K
FCF MarginFCF / Revenue
10.4%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$1.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ENSC
ENSC
UG
UG
Q4 25
$-1.5M
$330.5K
Q3 25
$-1.9M
$1.0M
Q2 25
$-2.7M
$303.2K
Q1 25
$-1.7M
$322.1K
Q4 24
$-764.1K
$269.3K
Q3 24
$-1.0M
$1.2M
Q2 24
$1.3M
Q1 24
$644.1K
Free Cash Flow
ENSC
ENSC
UG
UG
Q4 25
$308.0K
Q3 25
$995.8K
Q2 25
$285.6K
Q1 25
$318.5K
Q4 24
$-45.9K
Q3 24
$1.2M
Q2 24
$1.3M
Q1 24
$622.2K
FCF Margin
ENSC
ENSC
UG
UG
Q4 25
10.4%
Q3 25
44.0%
Q2 25
10.1%
Q1 25
12.8%
Q4 24
-1.9%
Q3 24
39.2%
Q2 24
37.1%
Q1 24
19.1%
Capex Intensity
ENSC
ENSC
UG
UG
Q4 25
0.8%
Q3 25
0.7%
Q2 25
0.6%
Q1 25
0.1%
Q4 24
12.7%
Q3 24
1.0%
Q2 24
1.9%
Q1 24
0.7%
Cash Conversion
ENSC
ENSC
UG
UG
Q4 25
Q3 25
3.77×
Q2 25
0.48×
Q1 25
0.57×
Q4 24
Q3 24
-1.54×
1.42×
Q2 24
1.38×
Q1 24
0.70×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ENSC
ENSC

Segment breakdown not available.

UG
UG

Pharmaceuticals$1.6M53%
Other$1.4M47%

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