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Side-by-side financial comparison of ENANTA PHARMACEUTICALS INC (ENTA) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $18.6M, roughly 1.2× ENANTA PHARMACEUTICALS INC). Usio, Inc. runs the higher net margin — -6.7% vs -64.1%, a 57.4% gap on every dollar of revenue. On growth, ENANTA PHARMACEUTICALS INC posted the faster year-over-year revenue change (9.8% vs 8.2%). Usio, Inc. produced more free cash flow last quarter ($1.1M vs $-11.8M). Over the past eight quarters, ENANTA PHARMACEUTICALS INC's revenue compounded faster (4.5% CAGR vs 3.0%).

Enanta Pharmaceuticals Inc is a clinical-stage biotechnology company that develops innovative antiviral therapies for infectious diseases including hepatitis B virus, respiratory syncytial virus (RSV), and SARS-CoV-2. It operates primarily in the U.S. and global markets, partnering with pharmaceutical firms to advance its small molecule drug candidate pipeline for patients with unmet medical needs.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

ENTA vs USIO — Head-to-Head

Bigger by revenue
USIO
USIO
1.2× larger
USIO
$22.2M
$18.6M
ENTA
Growing faster (revenue YoY)
ENTA
ENTA
+1.6% gap
ENTA
9.8%
8.2%
USIO
Higher net margin
USIO
USIO
57.4% more per $
USIO
-6.7%
-64.1%
ENTA
More free cash flow
USIO
USIO
$12.9M more FCF
USIO
$1.1M
$-11.8M
ENTA
Faster 2-yr revenue CAGR
ENTA
ENTA
Annualised
ENTA
4.5%
3.0%
USIO

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ENTA
ENTA
USIO
USIO
Revenue
$18.6M
$22.2M
Net Profit
$-11.9M
$-1.5M
Gross Margin
21.9%
Operating Margin
-60.5%
-5.7%
Net Margin
-64.1%
-6.7%
Revenue YoY
9.8%
8.2%
Net Profit YoY
46.4%
-337.8%
EPS (diluted)
$-0.42
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ENTA
ENTA
USIO
USIO
Q4 25
$18.6M
$22.2M
Q3 25
$15.1M
$21.2M
Q2 25
$18.3M
$20.0M
Q1 25
$14.9M
$22.0M
Q4 24
$17.0M
$20.6M
Q3 24
$14.6M
$21.3M
Q2 24
$18.0M
$20.1M
Q1 24
$17.1M
$21.0M
Net Profit
ENTA
ENTA
USIO
USIO
Q4 25
$-11.9M
$-1.5M
Q3 25
$-18.7M
$-415.1K
Q2 25
$-18.3M
$-366.7K
Q1 25
$-22.6M
$-235.0K
Q4 24
$-22.3M
$628.9K
Q3 24
$-28.8M
$2.9M
Q2 24
$-22.7M
$75.5K
Q1 24
$-31.2M
$-250.2K
Gross Margin
ENTA
ENTA
USIO
USIO
Q4 25
21.9%
Q3 25
23.0%
Q2 25
25.8%
Q1 25
21.9%
Q4 24
24.6%
Q3 24
23.0%
Q2 24
23.9%
Q1 24
23.1%
Operating Margin
ENTA
ENTA
USIO
USIO
Q4 25
-60.5%
-5.7%
Q3 25
-121.6%
-2.2%
Q2 25
-103.2%
-2.0%
Q1 25
-164.3%
-1.1%
Q4 24
-138.8%
-2.9%
Q3 24
-204.4%
-1.8%
Q2 24
-134.6%
-1.0%
Q1 24
-192.1%
-1.3%
Net Margin
ENTA
ENTA
USIO
USIO
Q4 25
-64.1%
-6.7%
Q3 25
-123.6%
-2.0%
Q2 25
-99.7%
-1.8%
Q1 25
-151.7%
-1.1%
Q4 24
-131.4%
3.1%
Q3 24
-197.3%
13.4%
Q2 24
-126.1%
0.4%
Q1 24
-182.7%
-1.2%
EPS (diluted)
ENTA
ENTA
USIO
USIO
Q4 25
$-0.42
$-0.05
Q3 25
$-0.88
$-0.02
Q2 25
$-0.85
$-0.01
Q1 25
$-1.06
$-0.01
Q4 24
$-1.05
$0.03
Q3 24
$-1.36
$0.10
Q2 24
$-1.07
$0.00
Q1 24
$-1.47
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ENTA
ENTA
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$37.4M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$126.6M
$17.9M
Total Assets
$329.5M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ENTA
ENTA
USIO
USIO
Q4 25
$37.4M
$7.4M
Q3 25
$32.3M
$7.7M
Q2 25
$44.8M
$8.1M
Q1 25
$60.2M
$8.7M
Q4 24
$84.3M
$8.1M
Q3 24
$37.2M
$8.4M
Q2 24
$35.8M
$7.2M
Q1 24
$63.5M
$7.1M
Total Debt
ENTA
ENTA
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
ENTA
ENTA
USIO
USIO
Q4 25
$126.6M
$17.9M
Q3 25
$64.7M
$18.7M
Q2 25
$79.3M
$18.7M
Q1 25
$93.5M
$19.0M
Q4 24
$111.8M
$19.2M
Q3 24
$128.8M
$18.9M
Q2 24
$148.9M
$15.7M
Q1 24
$166.1M
$15.3M
Total Assets
ENTA
ENTA
USIO
USIO
Q4 25
$329.5M
$134.9M
Q3 25
$280.7M
$99.4M
Q2 25
$301.0M
$108.4M
Q1 25
$323.0M
$109.6M
Q4 24
$348.6M
$107.2M
Q3 24
$376.7M
$114.6M
Q2 24
$398.8M
$108.8M
Q1 24
$413.6M
$99.1M
Debt / Equity
ENTA
ENTA
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ENTA
ENTA
USIO
USIO
Operating Cash FlowLast quarter
$-11.7M
$1.5M
Free Cash FlowOCF − Capex
$-11.8M
$1.1M
FCF MarginFCF / Revenue
-63.6%
4.8%
Capex IntensityCapex / Revenue
0.8%
2.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-18.5M
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ENTA
ENTA
USIO
USIO
Q4 25
$-11.7M
$1.5M
Q3 25
$-6.5M
$303.8K
Q2 25
$17.5M
$-263.9K
Q1 25
$-13.5M
$1.4M
Q4 24
$-16.8M
$2.9M
Q3 24
$-10.4M
$1.4M
Q2 24
$-14.8M
$369.1K
Q1 24
$-28.6M
$88.7K
Free Cash Flow
ENTA
ENTA
USIO
USIO
Q4 25
$-11.8M
$1.1M
Q3 25
$-7.9M
$85.2K
Q2 25
$17.4M
$-503.2K
Q1 25
$-16.0M
$1.1M
Q4 24
$-25.5M
$2.7M
Q3 24
$-19.4M
$1.4M
Q2 24
$-21.3M
$246.3K
Q1 24
$-30.3M
$-88.1K
FCF Margin
ENTA
ENTA
USIO
USIO
Q4 25
-63.6%
4.8%
Q3 25
-52.5%
0.4%
Q2 25
94.7%
-2.5%
Q1 25
-107.4%
4.8%
Q4 24
-150.6%
13.1%
Q3 24
-132.5%
6.4%
Q2 24
-118.6%
1.2%
Q1 24
-177.5%
-0.4%
Capex Intensity
ENTA
ENTA
USIO
USIO
Q4 25
0.8%
2.0%
Q3 25
9.6%
1.0%
Q2 25
0.8%
1.2%
Q1 25
17.0%
1.4%
Q4 24
51.6%
1.0%
Q3 24
61.3%
0.3%
Q2 24
36.4%
0.6%
Q1 24
9.8%
0.8%
Cash Conversion
ENTA
ENTA
USIO
USIO
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
4.61×
Q3 24
0.50×
Q2 24
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ENTA
ENTA

Segment breakdown not available.

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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