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Side-by-side financial comparison of Esperion Therapeutics, Inc. (ESPR) and FIRST INTERSTATE BANCSYSTEM INC (FIBK). Click either name above to swap in a different company.

FIRST INTERSTATE BANCSYSTEM INC is the larger business by last-quarter revenue ($313.0M vs $168.4M, roughly 1.9× Esperion Therapeutics, Inc.). On growth, Esperion Therapeutics, Inc. posted the faster year-over-year revenue change (143.7% vs 19.8%). Over the past eight quarters, FIRST INTERSTATE BANCSYSTEM INC's revenue compounded faster (13.7% CAGR vs 10.6%).

Esperion Therapeutics, Inc. is a publicly traded American pharmaceutical company focused on the development of bempedoic acid, an orally available small molecule designed to lower elevated levels of LDL-C. The company is headquartered in Ann Arbor, Michigan.

First Interstate BancSystem, Inc. is a financial holding company headquartered in Billings, Montana. It is the parent company of First Interstate Bank, a community bank with locations throughout 14 states within the Western and Midwestern United States. It is the largest bank based in Montana, as measured by total assets.

ESPR vs FIBK — Head-to-Head

Bigger by revenue
FIBK
FIBK
1.9× larger
FIBK
$313.0M
$168.4M
ESPR
Growing faster (revenue YoY)
ESPR
ESPR
+123.9% gap
ESPR
143.7%
19.8%
FIBK
Faster 2-yr revenue CAGR
FIBK
FIBK
Annualised
FIBK
13.7%
10.6%
ESPR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ESPR
ESPR
FIBK
FIBK
Revenue
$168.4M
$313.0M
Net Profit
$108.8M
Gross Margin
Operating Margin
50.6%
44.5%
Net Margin
34.8%
Revenue YoY
143.7%
19.8%
Net Profit YoY
108.8%
EPS (diluted)
$0.32
$1.07

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESPR
ESPR
FIBK
FIBK
Q4 25
$168.4M
$313.0M
Q3 25
$87.3M
$250.5M
Q2 25
$82.4M
$248.3M
Q1 25
$65.0M
$247.0M
Q4 24
$69.1M
$261.3M
Q3 24
$51.6M
$251.9M
Q2 24
$73.8M
$244.3M
Q1 24
$137.7M
$242.2M
Net Profit
ESPR
ESPR
FIBK
FIBK
Q4 25
$108.8M
Q3 25
$-31.3M
$71.4M
Q2 25
$-12.7M
$71.7M
Q1 25
$-40.5M
$50.2M
Q4 24
$52.1M
Q3 24
$-29.5M
$55.5M
Q2 24
$-61.9M
$60.0M
Q1 24
$61.0M
$58.4M
Operating Margin
ESPR
ESPR
FIBK
FIBK
Q4 25
50.6%
44.5%
Q3 25
-11.4%
37.0%
Q2 25
8.6%
37.7%
Q1 25
-34.0%
26.9%
Q4 24
-6.4%
25.5%
Q3 24
-31.0%
28.9%
Q2 24
3.5%
32.1%
Q1 24
52.5%
31.7%
Net Margin
ESPR
ESPR
FIBK
FIBK
Q4 25
34.8%
Q3 25
-35.9%
28.5%
Q2 25
-15.4%
28.9%
Q1 25
-62.2%
20.3%
Q4 24
19.9%
Q3 24
-57.2%
22.0%
Q2 24
-83.9%
24.6%
Q1 24
44.3%
24.1%
EPS (diluted)
ESPR
ESPR
FIBK
FIBK
Q4 25
$0.32
$1.07
Q3 25
$-0.16
$0.69
Q2 25
$-0.06
$0.69
Q1 25
$-0.21
$0.49
Q4 24
$-0.14
$0.50
Q3 24
$-0.15
$0.54
Q2 24
$-0.33
$0.58
Q1 24
$0.34
$0.57

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESPR
ESPR
FIBK
FIBK
Cash + ST InvestmentsLiquidity on hand
$167.9M
Total DebtLower is stronger
$146.3M
Stockholders' EquityBook value
$-302.0M
$3.4B
Total Assets
$465.9M
$26.6B
Debt / EquityLower = less leverage
0.04×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESPR
ESPR
FIBK
FIBK
Q4 25
$167.9M
Q3 25
$92.4M
Q2 25
$86.1M
Q1 25
$114.6M
Q4 24
$144.8M
Q3 24
$144.7M
Q2 24
$189.3M
Q1 24
$226.6M
Total Debt
ESPR
ESPR
FIBK
FIBK
Q4 25
$146.3M
Q3 25
$146.2M
Q2 25
$252.0M
Q1 25
Q4 24
$132.2M
Q3 24
$137.3M
Q2 24
$383.4M
Q1 24
$370.8M
Stockholders' Equity
ESPR
ESPR
FIBK
FIBK
Q4 25
$-302.0M
$3.4B
Q3 25
$-451.4M
$3.4B
Q2 25
$-433.5M
$3.4B
Q1 25
$-426.2M
$3.4B
Q4 24
$-388.7M
$3.3B
Q3 24
$-370.2M
$3.4B
Q2 24
$-344.2M
$3.2B
Q1 24
$-294.3M
$3.2B
Total Assets
ESPR
ESPR
FIBK
FIBK
Q4 25
$465.9M
$26.6B
Q3 25
$364.0M
$27.3B
Q2 25
$347.1M
$27.6B
Q1 25
$324.0M
$28.3B
Q4 24
$343.8M
$29.1B
Q3 24
$314.1M
$29.6B
Q2 24
$352.3M
$30.3B
Q1 24
$373.1M
$30.1B
Debt / Equity
ESPR
ESPR
FIBK
FIBK
Q4 25
0.04×
Q3 25
0.04×
Q2 25
0.07×
Q1 25
Q4 24
0.04×
Q3 24
0.04×
Q2 24
0.12×
Q1 24
0.12×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESPR
ESPR
FIBK
FIBK
Operating Cash FlowLast quarter
$45.2M
$305.6M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
2.81×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESPR
ESPR
FIBK
FIBK
Q4 25
$45.2M
$305.6M
Q3 25
$-4.3M
$91.7M
Q2 25
$-31.4M
$68.1M
Q1 25
$-22.6M
$78.5M
Q4 24
$-35.0M
$355.0M
Q3 24
$-35.3M
$89.9M
Q2 24
$-7.2M
$82.3M
Q1 24
$53.8M
$87.6M
Free Cash Flow
ESPR
ESPR
FIBK
FIBK
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
$-35.5M
Q2 24
$-7.3M
Q1 24
$53.8M
FCF Margin
ESPR
ESPR
FIBK
FIBK
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-68.7%
Q2 24
-9.9%
Q1 24
39.0%
Capex Intensity
ESPR
ESPR
FIBK
FIBK
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
0.0%
Q3 24
0.3%
Q2 24
0.1%
Q1 24
0.1%
Cash Conversion
ESPR
ESPR
FIBK
FIBK
Q4 25
2.81×
Q3 25
1.28×
Q2 25
0.95×
Q1 25
1.56×
Q4 24
6.81×
Q3 24
1.62×
Q2 24
1.37×
Q1 24
0.88×
1.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESPR
ESPR

Collaboration Revenue$124.7M74%
Products$43.7M26%

FIBK
FIBK

Segment breakdown not available.

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