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Side-by-side financial comparison of Esperion Therapeutics, Inc. (ESPR) and James River Group Holdings, Inc. (JRVR). Click either name above to swap in a different company.

Esperion Therapeutics, Inc. is the larger business by last-quarter revenue ($168.4M vs $167.7M, roughly 1.0× James River Group Holdings, Inc.). On growth, Esperion Therapeutics, Inc. posted the faster year-over-year revenue change (143.7% vs 32.4%). Over the past eight quarters, Esperion Therapeutics, Inc.'s revenue compounded faster (10.6% CAGR vs -8.7%).

Esperion Therapeutics, Inc. is a publicly traded American pharmaceutical company focused on the development of bempedoic acid, an orally available small molecule designed to lower elevated levels of LDL-C. The company is headquartered in Ann Arbor, Michigan.

James River Corporation was an American pulp and paper company based in Richmond, Virginia, once the largest paper manufacturer in the world.

ESPR vs JRVR — Head-to-Head

Bigger by revenue
ESPR
ESPR
1.0× larger
ESPR
$168.4M
$167.7M
JRVR
Growing faster (revenue YoY)
ESPR
ESPR
+111.3% gap
ESPR
143.7%
32.4%
JRVR
Faster 2-yr revenue CAGR
ESPR
ESPR
Annualised
ESPR
10.6%
-8.7%
JRVR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ESPR
ESPR
JRVR
JRVR
Revenue
$168.4M
$167.7M
Net Profit
$32.1M
Gross Margin
Operating Margin
50.6%
14.6%
Net Margin
19.1%
Revenue YoY
143.7%
32.4%
Net Profit YoY
149.5%
EPS (diluted)
$0.32
$0.59

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESPR
ESPR
JRVR
JRVR
Q4 25
$168.4M
$167.7M
Q3 25
$87.3M
$172.7M
Q2 25
$82.4M
$174.8M
Q1 25
$65.0M
$172.3M
Q4 24
$69.1M
$126.7M
Q3 24
$51.6M
$191.5M
Q2 24
$73.8M
$188.3M
Q1 24
$137.7M
$201.1M
Net Profit
ESPR
ESPR
JRVR
JRVR
Q4 25
$32.1M
Q3 25
$-31.3M
$1.0M
Q2 25
$-12.7M
$4.8M
Q1 25
$-40.5M
$9.6M
Q4 24
$-64.8M
Q3 24
$-29.5M
$-39.4M
Q2 24
$-61.9M
$7.6M
Q1 24
$61.0M
$15.4M
Operating Margin
ESPR
ESPR
JRVR
JRVR
Q4 25
50.6%
14.6%
Q3 25
-11.4%
1.5%
Q2 25
8.6%
4.2%
Q1 25
-34.0%
9.3%
Q4 24
-6.4%
-57.0%
Q3 24
-31.0%
-27.1%
Q2 24
3.5%
10.7%
Q1 24
52.5%
16.4%
Net Margin
ESPR
ESPR
JRVR
JRVR
Q4 25
19.1%
Q3 25
-35.9%
0.6%
Q2 25
-15.4%
2.7%
Q1 25
-62.2%
5.6%
Q4 24
-51.1%
Q3 24
-57.2%
-20.6%
Q2 24
-83.9%
4.0%
Q1 24
44.3%
7.7%
EPS (diluted)
ESPR
ESPR
JRVR
JRVR
Q4 25
$0.32
$0.59
Q3 25
$-0.16
$-0.02
Q2 25
$-0.06
$0.06
Q1 25
$-0.21
$0.16
Q4 24
$-0.14
$-2.44
Q3 24
$-0.15
$-1.10
Q2 24
$-0.33
$0.13
Q1 24
$0.34
$0.35

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESPR
ESPR
JRVR
JRVR
Cash + ST InvestmentsLiquidity on hand
$167.9M
$260.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$-302.0M
$538.2M
Total Assets
$465.9M
$4.9B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESPR
ESPR
JRVR
JRVR
Q4 25
$167.9M
$260.9M
Q3 25
$92.4M
$238.8M
Q2 25
$86.1M
$220.0M
Q1 25
$114.6M
$279.4M
Q4 24
$144.8M
$362.3M
Q3 24
$144.7M
$359.8M
Q2 24
$189.3M
$672.5M
Q1 24
$226.6M
$305.5M
Stockholders' Equity
ESPR
ESPR
JRVR
JRVR
Q4 25
$-302.0M
$538.2M
Q3 25
$-451.4M
$503.6M
Q2 25
$-433.5M
$492.6M
Q1 25
$-426.2M
$484.5M
Q4 24
$-388.7M
$460.9M
Q3 24
$-370.2M
$530.3M
Q2 24
$-344.2M
$541.8M
Q1 24
$-294.3M
$539.5M
Total Assets
ESPR
ESPR
JRVR
JRVR
Q4 25
$465.9M
$4.9B
Q3 25
$364.0M
$5.0B
Q2 25
$347.1M
$5.0B
Q1 25
$324.0M
$4.9B
Q4 24
$343.8M
$5.0B
Q3 24
$314.1M
$5.0B
Q2 24
$352.3M
$4.7B
Q1 24
$373.1M
$5.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESPR
ESPR
JRVR
JRVR
Operating Cash FlowLast quarter
$45.2M
$-18.8M
Free Cash FlowOCF − Capex
$-23.6M
FCF MarginFCF / Revenue
-14.1%
Capex IntensityCapex / Revenue
0.0%
2.9%
Cash ConversionOCF / Net Profit
-0.59×
TTM Free Cash FlowTrailing 4 quarters
$-17.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESPR
ESPR
JRVR
JRVR
Q4 25
$45.2M
$-18.8M
Q3 25
$-4.3M
$34.3M
Q2 25
$-31.4M
$25.2M
Q1 25
$-22.6M
$-51.5M
Q4 24
$-35.0M
$-247.1M
Q3 24
$-35.3M
$-269.9M
Q2 24
$-7.2M
$-8.7M
Q1 24
$53.8M
$24.1M
Free Cash Flow
ESPR
ESPR
JRVR
JRVR
Q4 25
$-23.6M
Q3 25
$33.7M
Q2 25
$24.7M
Q1 25
$-52.7M
Q4 24
$-252.0M
Q3 24
$-35.5M
$-270.8M
Q2 24
$-7.3M
$-9.3M
Q1 24
$53.8M
$23.3M
FCF Margin
ESPR
ESPR
JRVR
JRVR
Q4 25
-14.1%
Q3 25
19.5%
Q2 25
14.1%
Q1 25
-30.6%
Q4 24
-198.9%
Q3 24
-68.7%
-141.4%
Q2 24
-9.9%
-4.9%
Q1 24
39.0%
11.6%
Capex Intensity
ESPR
ESPR
JRVR
JRVR
Q4 25
0.0%
2.9%
Q3 25
0.0%
0.4%
Q2 25
0.0%
0.3%
Q1 25
0.0%
0.7%
Q4 24
0.0%
3.9%
Q3 24
0.3%
0.4%
Q2 24
0.1%
0.3%
Q1 24
0.1%
0.4%
Cash Conversion
ESPR
ESPR
JRVR
JRVR
Q4 25
-0.59×
Q3 25
33.61×
Q2 25
5.29×
Q1 25
-5.38×
Q4 24
Q3 24
Q2 24
-1.14×
Q1 24
0.88×
1.56×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESPR
ESPR

Collaboration Revenue$124.7M74%
Products$43.7M26%

JRVR
JRVR

Excess And Surplus Lines$156.7M93%
Specialty Admitted Insurance$10.9M7%

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