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Side-by-side financial comparison of Esperion Therapeutics, Inc. (ESPR) and Pacira BioSciences, Inc. (PCRX). Click either name above to swap in a different company.

Pacira BioSciences, Inc. is the larger business by last-quarter revenue ($177.4M vs $168.4M, roughly 1.1× Esperion Therapeutics, Inc.). On growth, Esperion Therapeutics, Inc. posted the faster year-over-year revenue change (143.7% vs 5.0%). Over the past eight quarters, Esperion Therapeutics, Inc.'s revenue compounded faster (10.6% CAGR vs -0.2%).

Esperion Therapeutics, Inc. is a publicly traded American pharmaceutical company focused on the development of bempedoic acid, an orally available small molecule designed to lower elevated levels of LDL-C. The company is headquartered in Ann Arbor, Michigan.

Pacira BioSciences, Inc. is a specialty pharmaceutical company focused on developing and commercializing non-opioid pain management solutions. Its core product line targets post-surgical pain relief for patients, serving hospitals, ambulatory surgery centers and other healthcare providers primarily in the U.S., with ongoing expansion efforts in select international markets.

ESPR vs PCRX — Head-to-Head

Bigger by revenue
PCRX
PCRX
1.1× larger
PCRX
$177.4M
$168.4M
ESPR
Growing faster (revenue YoY)
ESPR
ESPR
+138.7% gap
ESPR
143.7%
5.0%
PCRX
Faster 2-yr revenue CAGR
ESPR
ESPR
Annualised
ESPR
10.6%
-0.2%
PCRX

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ESPR
ESPR
PCRX
PCRX
Revenue
$168.4M
$177.4M
Net Profit
$2.9M
Gross Margin
Operating Margin
50.6%
3.9%
Net Margin
1.6%
Revenue YoY
143.7%
5.0%
Net Profit YoY
EPS (diluted)
$0.32
$0.07

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESPR
ESPR
PCRX
PCRX
Q1 26
$177.4M
Q4 25
$168.4M
$196.9M
Q3 25
$87.3M
$179.5M
Q2 25
$82.4M
$181.1M
Q1 25
$65.0M
$168.9M
Q4 24
$69.1M
$187.3M
Q3 24
$51.6M
$168.6M
Q2 24
$73.8M
$178.0M
Net Profit
ESPR
ESPR
PCRX
PCRX
Q1 26
$2.9M
Q4 25
Q3 25
$-31.3M
$5.4M
Q2 25
$-12.7M
$-4.8M
Q1 25
$-40.5M
$4.8M
Q4 24
Q3 24
$-29.5M
$-143.5M
Q2 24
$-61.9M
$18.9M
Gross Margin
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
79.5%
Q3 25
80.9%
Q2 25
77.4%
Q1 25
79.7%
Q4 24
78.7%
Q3 24
76.9%
Q2 24
75.1%
Operating Margin
ESPR
ESPR
PCRX
PCRX
Q1 26
3.9%
Q4 25
50.6%
1.2%
Q3 25
-11.4%
3.5%
Q2 25
8.6%
4.7%
Q1 25
-34.0%
1.2%
Q4 24
-6.4%
13.2%
Q3 24
-31.0%
-82.8%
Q2 24
3.5%
15.9%
Net Margin
ESPR
ESPR
PCRX
PCRX
Q1 26
1.6%
Q4 25
Q3 25
-35.9%
3.0%
Q2 25
-15.4%
-2.7%
Q1 25
-62.2%
2.8%
Q4 24
Q3 24
-57.2%
-85.1%
Q2 24
-83.9%
10.6%
EPS (diluted)
ESPR
ESPR
PCRX
PCRX
Q1 26
$0.07
Q4 25
$0.32
$0.05
Q3 25
$-0.16
$0.12
Q2 25
$-0.06
$-0.11
Q1 25
$-0.21
$0.10
Q4 24
$-0.14
$0.38
Q3 24
$-0.15
$-3.11
Q2 24
$-0.33
$0.39

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESPR
ESPR
PCRX
PCRX
Cash + ST InvestmentsLiquidity on hand
$167.9M
$144.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$-302.0M
$653.9M
Total Assets
$465.9M
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESPR
ESPR
PCRX
PCRX
Q1 26
$144.3M
Q4 25
$167.9M
$238.4M
Q3 25
$92.4M
$246.3M
Q2 25
$86.1M
$445.9M
Q1 25
$114.6M
$493.6M
Q4 24
$144.8M
$484.6M
Q3 24
$144.7M
$453.8M
Q2 24
$189.3M
$404.2M
Total Debt
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
$372.2M
Q3 25
$376.7M
Q2 25
$580.5M
Q1 25
$583.4M
Q4 24
$585.3M
Q3 24
Q2 24
Stockholders' Equity
ESPR
ESPR
PCRX
PCRX
Q1 26
$653.9M
Q4 25
$-302.0M
$693.1M
Q3 25
$-451.4M
$727.2M
Q2 25
$-433.5M
$757.8M
Q1 25
$-426.2M
$798.5M
Q4 24
$-388.7M
$778.3M
Q3 24
$-370.2M
$749.6M
Q2 24
$-344.2M
$879.3M
Total Assets
ESPR
ESPR
PCRX
PCRX
Q1 26
$1.2B
Q4 25
$465.9M
$1.3B
Q3 25
$364.0M
$1.3B
Q2 25
$347.1M
$1.5B
Q1 25
$324.0M
$1.6B
Q4 24
$343.8M
$1.6B
Q3 24
$314.1M
$1.5B
Q2 24
$352.3M
$1.6B
Debt / Equity
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
0.54×
Q3 25
0.52×
Q2 25
0.77×
Q1 25
0.73×
Q4 24
0.75×
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESPR
ESPR
PCRX
PCRX
Operating Cash FlowLast quarter
$45.2M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
$45.2M
$43.7M
Q3 25
$-4.3M
$60.8M
Q2 25
$-31.4M
$12.0M
Q1 25
$-22.6M
$35.5M
Q4 24
$-35.0M
$33.1M
Q3 24
$-35.3M
$53.9M
Q2 24
$-7.2M
$53.2M
Free Cash Flow
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
$43.5M
Q3 25
$57.0M
Q2 25
$9.3M
Q1 25
$26.9M
Q4 24
$31.0M
Q3 24
$-35.5M
$49.8M
Q2 24
$-7.3M
$51.6M
FCF Margin
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
22.1%
Q3 25
31.7%
Q2 25
5.1%
Q1 25
15.9%
Q4 24
16.6%
Q3 24
-68.7%
29.6%
Q2 24
-9.9%
29.0%
Capex Intensity
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
0.0%
0.1%
Q3 25
0.0%
2.2%
Q2 25
0.0%
1.5%
Q1 25
0.0%
5.1%
Q4 24
0.0%
1.1%
Q3 24
0.3%
2.4%
Q2 24
0.1%
0.9%
Cash Conversion
ESPR
ESPR
PCRX
PCRX
Q1 26
Q4 25
Q3 25
11.20×
Q2 25
Q1 25
7.37×
Q4 24
Q3 24
Q2 24
2.82×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESPR
ESPR

Collaboration Revenue$124.7M74%
Products$43.7M26%

PCRX
PCRX

EXPAREL$143.3M81%
ZILRETTA$26.8M15%
iovera°$6.2M3%
Bupivacaine liposome injectable suspension$1.2M1%

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