vs

Side-by-side financial comparison of EXELIXIS, INC. (EXEL) and TRUPANION, INC. (TRUP). Click either name above to swap in a different company.

EXELIXIS, INC. is the larger business by last-quarter revenue ($598.7M vs $376.9M, roughly 1.6× TRUPANION, INC.). On growth, TRUPANION, INC. posted the faster year-over-year revenue change (11.7% vs 5.6%). EXELIXIS, INC. produced more free cash flow last quarter ($332.4M vs $25.3M). Over the past eight quarters, EXELIXIS, INC.'s revenue compounded faster (18.7% CAGR vs 11.0%).

Exelixis, Inc. is a genomics-based drug discovery company located in Alameda, California, and the producer of Cometriq, a treatment approved by the U.S. Food and Drug Administration (FDA) for medullary thyroid cancer with clinical activity in several other types of metastatic cancer.

Trupanion, Inc. is a pet insurance provider headquartered in Seattle, Washington. Established in 1998, Trupanion operates across the United States, Canada, Australia, and Puerto Rico. The company offers coverage for pets and is self-underwritten by the American Pet Insurance Company (APIC).

EXEL vs TRUP — Head-to-Head

Bigger by revenue
EXEL
EXEL
1.6× larger
EXEL
$598.7M
$376.9M
TRUP
Growing faster (revenue YoY)
TRUP
TRUP
+6.1% gap
TRUP
11.7%
5.6%
EXEL
More free cash flow
EXEL
EXEL
$307.0M more FCF
EXEL
$332.4M
$25.3M
TRUP
Faster 2-yr revenue CAGR
EXEL
EXEL
Annualised
EXEL
18.7%
11.0%
TRUP

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
EXEL
EXEL
TRUP
TRUP
Revenue
$598.7M
$376.9M
Net Profit
$244.5M
Gross Margin
95.6%
17.3%
Operating Margin
39.3%
1.9%
Net Margin
40.8%
Revenue YoY
5.6%
11.7%
Net Profit YoY
74.8%
EPS (diluted)
$0.89
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
EXEL
EXEL
TRUP
TRUP
Q1 26
$598.7M
Q4 25
$597.8M
$376.9M
Q3 25
$568.3M
$366.9M
Q2 25
$555.4M
$353.6M
Q1 25
$566.8M
$342.0M
Q4 24
$337.3M
Q3 24
$539.5M
$327.5M
Q2 24
$637.2M
$314.8M
Net Profit
EXEL
EXEL
TRUP
TRUP
Q1 26
$244.5M
Q4 25
$193.6M
Q3 25
$184.8M
Q2 25
$159.6M
Q1 25
$139.9M
Q4 24
Q3 24
$118.0M
Q2 24
$226.1M
Gross Margin
EXEL
EXEL
TRUP
TRUP
Q1 26
95.6%
Q4 25
96.9%
17.3%
Q3 25
96.6%
16.4%
Q2 25
96.5%
15.5%
Q1 25
96.5%
14.9%
Q4 24
15.7%
Q3 24
96.8%
15.1%
Q2 24
97.2%
12.8%
Operating Margin
EXEL
EXEL
TRUP
TRUP
Q1 26
39.3%
Q4 25
39.6%
1.9%
Q3 25
37.6%
1.6%
Q2 25
33.6%
0.7%
Q1 25
28.8%
-0.4%
Q4 24
0.1%
Q3 24
25.2%
0.5%
Q2 24
43.3%
-1.7%
Net Margin
EXEL
EXEL
TRUP
TRUP
Q1 26
40.8%
Q4 25
32.4%
Q3 25
32.5%
Q2 25
28.7%
Q1 25
24.7%
Q4 24
Q3 24
21.9%
Q2 24
35.5%
EPS (diluted)
EXEL
EXEL
TRUP
TRUP
Q1 26
$0.89
Q4 25
$0.69
$0.13
Q3 25
$0.65
$0.13
Q2 25
$0.55
$0.22
Q1 25
$0.47
$-0.03
Q4 24
$0.04
Q3 24
$0.40
$0.03
Q2 24
$0.77
$-0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
EXEL
EXEL
TRUP
TRUP
Cash + ST InvestmentsLiquidity on hand
$1.1B
$370.7M
Total DebtLower is stronger
$101.8M
Stockholders' EquityBook value
$2.2B
$383.9M
Total Assets
$2.8B
$915.0M
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
EXEL
EXEL
TRUP
TRUP
Q1 26
$1.1B
Q4 25
$988.5M
$370.7M
Q3 25
$791.1M
$348.5M
Q2 25
$1.0B
$319.6M
Q1 25
$1.1B
$321.8M
Q4 24
$307.4M
Q3 24
$1.2B
$293.1M
Q2 24
$1.0B
$277.2M
Total Debt
EXEL
EXEL
TRUP
TRUP
Q1 26
Q4 25
$101.8M
Q3 25
Q2 25
Q1 25
Q4 24
$127.5M
Q3 24
Q2 24
Stockholders' Equity
EXEL
EXEL
TRUP
TRUP
Q1 26
$2.2B
Q4 25
$2.2B
$383.9M
Q3 25
$2.0B
$368.6M
Q2 25
$2.1B
$355.5M
Q1 25
$2.2B
$333.7M
Q4 24
$323.3M
Q3 24
$2.3B
$320.2M
Q2 24
$2.1B
$305.8M
Total Assets
EXEL
EXEL
TRUP
TRUP
Q1 26
$2.8B
Q4 25
$2.8B
$915.0M
Q3 25
$2.7B
$880.2M
Q2 25
$2.8B
$847.8M
Q1 25
$2.9B
$837.2M
Q4 24
$806.9M
Q3 24
$3.0B
$816.1M
Q2 24
$2.8B
$795.9M
Debt / Equity
EXEL
EXEL
TRUP
TRUP
Q1 26
Q4 25
0.27×
Q3 25
Q2 25
Q1 25
Q4 24
0.39×
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
EXEL
EXEL
TRUP
TRUP
Operating Cash FlowLast quarter
$333.5M
$29.3M
Free Cash FlowOCF − Capex
$332.4M
$25.3M
FCF MarginFCF / Revenue
55.5%
6.7%
Capex IntensityCapex / Revenue
0.2%
1.0%
Cash ConversionOCF / Net Profit
1.36×
TTM Free Cash FlowTrailing 4 quarters
$875.8M
$75.4M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
EXEL
EXEL
TRUP
TRUP
Q1 26
$333.5M
Q4 25
$290.3M
$29.3M
Q3 25
$49.0M
$29.2M
Q2 25
$211.4M
$15.0M
Q1 25
$240.3M
$16.0M
Q4 24
$23.7M
Q3 24
$271.3M
$15.3M
Q2 24
$119.5M
$6.9M
Free Cash Flow
EXEL
EXEL
TRUP
TRUP
Q1 26
$332.4M
Q4 25
$288.8M
$25.3M
Q3 25
$46.2M
$23.9M
Q2 25
$208.5M
$12.0M
Q1 25
$236.3M
$14.0M
Q4 24
$21.8M
Q3 24
$263.1M
$13.4M
Q2 24
$113.0M
$4.0M
FCF Margin
EXEL
EXEL
TRUP
TRUP
Q1 26
55.5%
Q4 25
48.3%
6.7%
Q3 25
8.1%
6.5%
Q2 25
37.5%
3.4%
Q1 25
41.7%
4.1%
Q4 24
6.5%
Q3 24
48.8%
4.1%
Q2 24
17.7%
1.3%
Capex Intensity
EXEL
EXEL
TRUP
TRUP
Q1 26
0.2%
Q4 25
0.2%
1.0%
Q3 25
0.5%
1.4%
Q2 25
0.5%
0.8%
Q1 25
0.7%
0.6%
Q4 24
0.6%
Q3 24
1.5%
0.6%
Q2 24
1.0%
0.9%
Cash Conversion
EXEL
EXEL
TRUP
TRUP
Q1 26
1.36×
Q4 25
1.50×
Q3 25
0.27×
Q2 25
1.32×
Q1 25
1.72×
Q4 24
Q3 24
2.30×
Q2 24
0.53×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

EXEL
EXEL

Cabometyx$544.7M91%
Collaboration$52.1M9%
Collaborative Arrangementwith Takeda$5.9M1%
Cometriq$1.8M0%

TRUP
TRUP

Subscriptionbusiness$261.4M69%
Other$115.4M31%

Related Comparisons