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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and OLAPLEX HOLDINGS, INC. (OLPX). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $105.1M, roughly 1.8× OLAPLEX HOLDINGS, INC.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -12.5%, a 13.4% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 4.3%). OLAPLEX HOLDINGS, INC. produced more free cash flow last quarter ($32.6M vs $16.0M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs 3.1%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Olaplex Holdings, Inc. is a specialty beauty company developing and selling patented bond-repair hair care products. It runs three core segments: professional salon distribution, direct-to-consumer sales, and third-party retail, serving customers across North America, Europe, and Asia-Pacific with products that repair and protect damaged hair.
FOLD vs OLPX — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $105.1M |
| Net Profit | $1.7M | $-13.1M |
| Gross Margin | 85.7% | 68.0% |
| Operating Margin | 8.6% | -4.3% |
| Net Margin | 0.9% | -12.5% |
| Revenue YoY | 23.7% | 4.3% |
| Net Profit YoY | -88.5% | -48.9% |
| EPS (diluted) | $0.00 | $-0.02 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $105.1M | ||
| Q3 25 | $169.1M | $114.6M | ||
| Q2 25 | $154.7M | $106.3M | ||
| Q1 25 | $125.2M | $97.0M | ||
| Q4 24 | $149.7M | $100.7M | ||
| Q3 24 | $141.5M | $119.1M | ||
| Q2 24 | $126.7M | $103.9M | ||
| Q1 24 | $110.4M | $98.9M |
| Q4 25 | $1.7M | $-13.1M | ||
| Q3 25 | $17.3M | $11.1M | ||
| Q2 25 | $-24.4M | $-7.7M | ||
| Q1 25 | $-21.7M | $465.0K | ||
| Q4 24 | $14.7M | $-8.8M | ||
| Q3 24 | $-6.7M | $14.8M | ||
| Q2 24 | $-15.7M | $5.8M | ||
| Q1 24 | $-48.4M | $7.7M |
| Q4 25 | 85.7% | 68.0% | ||
| Q3 25 | 88.5% | 69.1% | ||
| Q2 25 | 90.2% | 71.2% | ||
| Q1 25 | 90.7% | 69.5% | ||
| Q4 24 | 90.1% | 66.3% | ||
| Q3 24 | 90.6% | 68.6% | ||
| Q2 24 | 91.1% | 69.7% | ||
| Q1 24 | 87.7% | 72.1% |
| Q4 25 | 8.6% | -4.3% | ||
| Q3 25 | 20.3% | 3.7% | ||
| Q2 25 | -6.1% | -1.1% | ||
| Q1 25 | -6.3% | 8.7% | ||
| Q4 24 | 10.7% | 3.0% | ||
| Q3 24 | 15.3% | 23.5% | ||
| Q2 24 | 11.8% | 15.7% | ||
| Q1 24 | -25.1% | 19.8% |
| Q4 25 | 0.9% | -12.5% | ||
| Q3 25 | 10.2% | 9.7% | ||
| Q2 25 | -15.8% | -7.3% | ||
| Q1 25 | -17.3% | 0.5% | ||
| Q4 24 | 9.8% | -8.7% | ||
| Q3 24 | -4.8% | 12.4% | ||
| Q2 24 | -12.4% | 5.6% | ||
| Q1 24 | -43.9% | 7.8% |
| Q4 25 | $0.00 | $-0.02 | ||
| Q3 25 | $0.06 | $0.02 | ||
| Q2 25 | $-0.08 | $-0.01 | ||
| Q1 25 | $-0.07 | $0.00 | ||
| Q4 24 | $0.05 | $-0.01 | ||
| Q3 24 | $-0.02 | $0.02 | ||
| Q2 24 | $-0.05 | $0.01 | ||
| Q1 24 | $-0.16 | $0.01 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $318.7M |
| Total DebtLower is stronger | $392.7M | $352.3M |
| Stockholders' EquityBook value | $274.2M | $879.4M |
| Total Assets | $949.9M | $1.5B |
| Debt / EquityLower = less leverage | 1.43× | 0.40× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | $318.7M | ||
| Q3 25 | $263.8M | $286.4M | ||
| Q2 25 | $231.0M | $289.3M | ||
| Q1 25 | $250.6M | $580.9M | ||
| Q4 24 | $249.9M | $586.0M | ||
| Q3 24 | $249.8M | $538.8M | ||
| Q2 24 | $260.1M | $507.9M | ||
| Q1 24 | $239.6M | $507.5M |
| Q4 25 | $392.7M | $352.3M | ||
| Q3 25 | $392.0M | $352.1M | ||
| Q2 25 | $391.3M | $351.9M | ||
| Q1 25 | $390.7M | $649.1M | ||
| Q4 24 | $390.1M | $650.5M | ||
| Q3 24 | $389.5M | $651.8M | ||
| Q2 24 | $388.9M | $653.1M | ||
| Q1 24 | $388.4M | $654.4M |
| Q4 25 | $274.2M | $879.4M | ||
| Q3 25 | $230.4M | $888.7M | ||
| Q2 25 | $204.3M | $874.2M | ||
| Q1 25 | $193.6M | $878.3M | ||
| Q4 24 | $194.0M | $874.4M | ||
| Q3 24 | $178.8M | $879.7M | ||
| Q2 24 | $132.5M | $863.3M | ||
| Q1 24 | $130.7M | $855.7M |
| Q4 25 | $949.9M | $1.5B | ||
| Q3 25 | $868.8M | $1.5B | ||
| Q2 25 | $815.3M | $1.5B | ||
| Q1 25 | $789.8M | $1.8B | ||
| Q4 24 | $785.0M | $1.8B | ||
| Q3 24 | $786.6M | $1.8B | ||
| Q2 24 | $749.5M | $1.8B | ||
| Q1 24 | $721.8M | $1.8B |
| Q4 25 | 1.43× | 0.40× | ||
| Q3 25 | 1.70× | 0.40× | ||
| Q2 25 | 1.92× | 0.40× | ||
| Q1 25 | 2.02× | 0.74× | ||
| Q4 24 | 2.01× | 0.74× | ||
| Q3 24 | 2.18× | 0.74× | ||
| Q2 24 | 2.93× | 0.76× | ||
| Q1 24 | 2.97× | 0.76× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $32.7M |
| Free Cash FlowOCF − Capex | $16.0M | $32.6M |
| FCF MarginFCF / Revenue | 8.6% | 31.0% |
| Capex IntensityCapex / Revenue | 0.2% | 0.1% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $58.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $32.7M | ||
| Q3 25 | $35.7M | $8.0M | ||
| Q2 25 | $-26.5M | $20.9M | ||
| Q1 25 | $7.8M | $-2.9M | ||
| Q4 24 | $-3.9M | $49.7M | ||
| Q3 24 | $-23.0M | $33.5M | ||
| Q2 24 | $22.7M | $16.2M | ||
| Q1 24 | $-29.7M | $43.7M |
| Q4 25 | $16.0M | $32.6M | ||
| Q3 25 | $35.3M | $7.9M | ||
| Q2 25 | $-28.9M | $20.8M | ||
| Q1 25 | $7.5M | $-3.0M | ||
| Q4 24 | $-4.2M | $49.2M | ||
| Q3 24 | $-23.3M | $33.3M | ||
| Q2 24 | $21.6M | $16.1M | ||
| Q1 24 | $-31.5M | $43.3M |
| Q4 25 | 8.6% | 31.0% | ||
| Q3 25 | 20.9% | 6.9% | ||
| Q2 25 | -18.7% | 19.6% | ||
| Q1 25 | 6.0% | -3.1% | ||
| Q4 24 | -2.8% | 48.9% | ||
| Q3 24 | -16.5% | 28.0% | ||
| Q2 24 | 17.0% | 15.5% | ||
| Q1 24 | -28.5% | 43.7% |
| Q4 25 | 0.2% | 0.1% | ||
| Q3 25 | 0.2% | 0.1% | ||
| Q2 25 | 1.6% | 0.1% | ||
| Q1 25 | 0.2% | 0.0% | ||
| Q4 24 | 0.2% | 0.4% | ||
| Q3 24 | 0.3% | 0.1% | ||
| Q2 24 | 0.9% | 0.1% | ||
| Q1 24 | 1.6% | 0.5% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | 0.72× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | -6.27× | ||
| Q4 24 | -0.27× | — | ||
| Q3 24 | — | 2.26× | ||
| Q2 24 | — | 2.81× | ||
| Q1 24 | — | 5.64× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
OLPX
| Sales Channel Directly To Consumer | $43.6M | 42% |
| Sales Channel Through Intermediary Professional | $36.8M | 35% |
| Sales Channel Through Intermediary Specialty Retail | $24.7M | 23% |
