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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and SIMMONS FIRST NATIONAL CORP (SFNC). Click either name above to swap in a different company.
SIMMONS FIRST NATIONAL CORP is the larger business by last-quarter revenue ($197.3M vs $185.2M, roughly 1.1× AMICUS THERAPEUTICS, INC.). On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 19.6%). SIMMONS FIRST NATIONAL CORP produced more free cash flow last quarter ($411.4M vs $16.0M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs 0.6%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Simmons Bank is a bank with operations in Arkansas, Kansas, Missouri, Oklahoma, Tennessee, and Texas. It is the primary subsidiary of Simmons First National Corporation, a bank holding company.
FOLD vs SFNC — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $197.3M |
| Net Profit | $1.7M | — |
| Gross Margin | 85.7% | — |
| Operating Margin | 8.6% | — |
| Net Margin | 0.9% | — |
| Revenue YoY | 23.7% | 19.6% |
| Net Profit YoY | -88.5% | — |
| EPS (diluted) | $0.00 | $0.36 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $197.3M | ||
| Q3 25 | $169.1M | $186.7M | ||
| Q2 25 | $154.7M | $214.2M | ||
| Q1 25 | $125.2M | $209.6M | ||
| Q4 24 | $149.7M | $208.5M | ||
| Q3 24 | $141.5M | $174.8M | ||
| Q2 24 | $126.7M | $197.2M | ||
| Q1 24 | $110.4M | $195.1M |
| Q4 25 | $1.7M | — | ||
| Q3 25 | $17.3M | $-562.8M | ||
| Q2 25 | $-24.4M | $54.8M | ||
| Q1 25 | $-21.7M | $32.4M | ||
| Q4 24 | $14.7M | — | ||
| Q3 24 | $-6.7M | $24.7M | ||
| Q2 24 | $-15.7M | $40.8M | ||
| Q1 24 | $-48.4M | $38.9M |
| Q4 25 | 85.7% | — | ||
| Q3 25 | 88.5% | — | ||
| Q2 25 | 90.2% | — | ||
| Q1 25 | 90.7% | — | ||
| Q4 24 | 90.1% | — | ||
| Q3 24 | 90.6% | — | ||
| Q2 24 | 91.1% | — | ||
| Q1 24 | 87.7% | — |
| Q4 25 | 8.6% | — | ||
| Q3 25 | 20.3% | — | ||
| Q2 25 | -6.1% | — | ||
| Q1 25 | -6.3% | — | ||
| Q4 24 | 10.7% | — | ||
| Q3 24 | 15.3% | — | ||
| Q2 24 | 11.8% | — | ||
| Q1 24 | -25.1% | — |
| Q4 25 | 0.9% | — | ||
| Q3 25 | 10.2% | -301.5% | ||
| Q2 25 | -15.8% | 25.6% | ||
| Q1 25 | -17.3% | 15.5% | ||
| Q4 24 | 9.8% | — | ||
| Q3 24 | -4.8% | 14.1% | ||
| Q2 24 | -12.4% | 20.7% | ||
| Q1 24 | -43.9% | 19.9% |
| Q4 25 | $0.00 | $0.36 | ||
| Q3 25 | $0.06 | $-4.00 | ||
| Q2 25 | $-0.08 | $0.43 | ||
| Q1 25 | $-0.07 | $0.26 | ||
| Q4 24 | $0.05 | $0.38 | ||
| Q3 24 | $-0.02 | $0.20 | ||
| Q2 24 | $-0.05 | $0.32 | ||
| Q1 24 | $-0.16 | $0.31 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | — |
| Total DebtLower is stronger | $392.7M | $620.0M |
| Stockholders' EquityBook value | $274.2M | $3.4B |
| Total Assets | $949.9M | $24.5B |
| Debt / EquityLower = less leverage | 1.43× | 0.18× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | — | ||
| Q3 25 | $263.8M | — | ||
| Q2 25 | $231.0M | — | ||
| Q1 25 | $250.6M | — | ||
| Q4 24 | $249.9M | — | ||
| Q3 24 | $249.8M | — | ||
| Q2 24 | $260.1M | — | ||
| Q1 24 | $239.6M | — |
| Q4 25 | $392.7M | $620.0M | ||
| Q3 25 | $392.0M | $667.8M | ||
| Q2 25 | $391.3M | $1.0B | ||
| Q1 25 | $390.7M | $1.3B | ||
| Q4 24 | $390.1M | $1.1B | ||
| Q3 24 | $389.5M | $1.4B | ||
| Q2 24 | $388.9M | $1.7B | ||
| Q1 24 | $388.4M | $1.2B |
| Q4 25 | $274.2M | $3.4B | ||
| Q3 25 | $230.4M | $3.4B | ||
| Q2 25 | $204.3M | $3.5B | ||
| Q1 25 | $193.6M | $3.5B | ||
| Q4 24 | $194.0M | $3.5B | ||
| Q3 24 | $178.8M | $3.5B | ||
| Q2 24 | $132.5M | $3.5B | ||
| Q1 24 | $130.7M | $3.4B |
| Q4 25 | $949.9M | $24.5B | ||
| Q3 25 | $868.8M | $24.2B | ||
| Q2 25 | $815.3M | $26.7B | ||
| Q1 25 | $789.8M | $26.8B | ||
| Q4 24 | $785.0M | $26.9B | ||
| Q3 24 | $786.6M | $27.3B | ||
| Q2 24 | $749.5M | $27.4B | ||
| Q1 24 | $721.8M | $27.4B |
| Q4 25 | 1.43× | 0.18× | ||
| Q3 25 | 1.70× | 0.20× | ||
| Q2 25 | 1.92× | 0.28× | ||
| Q1 25 | 2.02× | 0.35× | ||
| Q4 24 | 2.01× | 0.32× | ||
| Q3 24 | 2.18× | 0.40× | ||
| Q2 24 | 2.93× | 0.50× | ||
| Q1 24 | 2.97× | 0.36× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $449.5M |
| Free Cash FlowOCF − Capex | $16.0M | $411.4M |
| FCF MarginFCF / Revenue | 8.6% | 208.5% |
| Capex IntensityCapex / Revenue | 0.2% | 19.3% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $717.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $449.5M | ||
| Q3 25 | $35.7M | $223.4M | ||
| Q2 25 | $-26.5M | $77.6M | ||
| Q1 25 | $7.8M | $32.8M | ||
| Q4 24 | $-3.9M | $425.9M | ||
| Q3 24 | $-23.0M | $199.4M | ||
| Q2 24 | $22.7M | $86.1M | ||
| Q1 24 | $-29.7M | $57.6M |
| Q4 25 | $16.0M | $411.4M | ||
| Q3 25 | $35.3M | $216.7M | ||
| Q2 25 | $-28.9M | $66.3M | ||
| Q1 25 | $7.5M | $22.6M | ||
| Q4 24 | $-4.2M | $380.4M | ||
| Q3 24 | $-23.3M | $187.7M | ||
| Q2 24 | $21.6M | $72.7M | ||
| Q1 24 | $-31.5M | $47.7M |
| Q4 25 | 8.6% | 208.5% | ||
| Q3 25 | 20.9% | 116.1% | ||
| Q2 25 | -18.7% | 31.0% | ||
| Q1 25 | 6.0% | 10.8% | ||
| Q4 24 | -2.8% | 182.5% | ||
| Q3 24 | -16.5% | 107.4% | ||
| Q2 24 | 17.0% | 36.9% | ||
| Q1 24 | -28.5% | 24.5% |
| Q4 25 | 0.2% | 19.3% | ||
| Q3 25 | 0.2% | 3.6% | ||
| Q2 25 | 1.6% | 5.3% | ||
| Q1 25 | 0.2% | 4.8% | ||
| Q4 24 | 0.2% | 21.8% | ||
| Q3 24 | 0.3% | 6.7% | ||
| Q2 24 | 0.9% | 6.8% | ||
| Q1 24 | 1.6% | 5.0% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | — | ||
| Q2 25 | — | 1.42× | ||
| Q1 25 | — | 1.01× | ||
| Q4 24 | -0.27× | — | ||
| Q3 24 | — | 8.06× | ||
| Q2 24 | — | 2.11× | ||
| Q1 24 | — | 1.48× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
SFNC
Segment breakdown not available.
