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Side-by-side financial comparison of ILLUMINA, INC. (ILMN) and SS&C Technologies Holdings Inc (SSNC). Click either name above to swap in a different company.

SS&C Technologies Holdings Inc is the larger business by last-quarter revenue ($1.6B vs $1.2B, roughly 1.4× ILLUMINA, INC.). ILLUMINA, INC. runs the higher net margin — 28.8% vs 13.7%, a 15.1% gap on every dollar of revenue. On growth, SS&C Technologies Holdings Inc posted the faster year-over-year revenue change (8.8% vs 5.0%). Over the past eight quarters, SS&C Technologies Holdings Inc's revenue compounded faster (6.5% CAGR vs -0.7%).

Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.

SS&C Technologies Holdings, Inc. is an American multinational holding company headquartered in Windsor, Connecticut, that sells software and software as a service to the financial services industry. The company has offices in the Americas, Europe, Asia, Africa and Australia.

ILMN vs SSNC — Head-to-Head

Bigger by revenue
SSNC
SSNC
1.4× larger
SSNC
$1.6B
$1.2B
ILMN
Growing faster (revenue YoY)
SSNC
SSNC
+3.8% gap
SSNC
8.8%
5.0%
ILMN
Higher net margin
ILMN
ILMN
15.1% more per $
ILMN
28.8%
13.7%
SSNC
Faster 2-yr revenue CAGR
SSNC
SSNC
Annualised
SSNC
6.5%
-0.7%
ILMN

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ILMN
ILMN
SSNC
SSNC
Revenue
$1.2B
$1.6B
Net Profit
$334.0M
$226.1M
Gross Margin
65.5%
48.7%
Operating Margin
17.4%
24.2%
Net Margin
28.8%
13.7%
Revenue YoY
5.0%
8.8%
Net Profit YoY
185.5%
6.2%
EPS (diluted)
$2.16
$0.91

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ILMN
ILMN
SSNC
SSNC
Q1 26
$1.6B
Q4 25
$1.2B
$1.7B
Q3 25
$1.6B
Q2 25
$1.5B
Q1 25
$1.5B
Q4 24
$1.1B
$1.5B
Q3 24
$1.1B
$1.5B
Q2 24
$1.1B
$1.5B
Net Profit
ILMN
ILMN
SSNC
SSNC
Q1 26
$226.1M
Q4 25
$334.0M
$193.1M
Q3 25
$210.0M
Q2 25
$180.8M
Q1 25
$213.0M
Q4 24
$186.0M
$248.2M
Q3 24
$705.0M
$164.4M
Q2 24
$-2.0B
$190.3M
Gross Margin
ILMN
ILMN
SSNC
SSNC
Q1 26
48.7%
Q4 25
65.5%
47.8%
Q3 25
47.7%
Q2 25
48.0%
Q1 25
49.3%
Q4 24
65.9%
49.3%
Q3 24
69.0%
48.0%
Q2 24
64.8%
48.1%
Operating Margin
ILMN
ILMN
SSNC
SSNC
Q1 26
24.2%
Q4 25
17.4%
22.3%
Q3 25
23.3%
Q2 25
22.4%
Q1 25
23.6%
Q4 24
15.8%
23.4%
Q3 24
68.6%
22.2%
Q2 24
-147.2%
22.6%
Net Margin
ILMN
ILMN
SSNC
SSNC
Q1 26
13.7%
Q4 25
28.8%
11.7%
Q3 25
13.4%
Q2 25
11.8%
Q1 25
14.1%
Q4 24
16.8%
16.2%
Q3 24
65.3%
11.2%
Q2 24
-178.8%
13.1%
EPS (diluted)
ILMN
ILMN
SSNC
SSNC
Q1 26
$0.91
Q4 25
$2.16
$0.76
Q3 25
$0.83
Q2 25
$0.72
Q1 25
$0.84
Q4 24
$1.16
$0.98
Q3 24
$4.42
$0.65
Q2 24
$-12.48
$0.75

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ILMN
ILMN
SSNC
SSNC
Cash + ST InvestmentsLiquidity on hand
$1.6B
$420.9M
Total DebtLower is stronger
$7.4B
Stockholders' EquityBook value
$2.7B
$6.9B
Total Assets
$6.6B
$20.3B
Debt / EquityLower = less leverage
1.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ILMN
ILMN
SSNC
SSNC
Q1 26
$420.9M
Q4 25
$1.6B
$462.1M
Q3 25
$388.3M
Q2 25
$480.3M
Q1 25
$515.0M
Q4 24
$93.0M
$567.1M
Q3 24
$70.0M
$694.7M
Q2 24
$74.0M
$462.7M
Total Debt
ILMN
ILMN
SSNC
SSNC
Q1 26
$7.4B
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Stockholders' Equity
ILMN
ILMN
SSNC
SSNC
Q1 26
$6.9B
Q4 25
$2.7B
$6.9B
Q3 25
$6.9B
Q2 25
$6.9B
Q1 25
$6.8B
Q4 24
$2.4B
$6.5B
Q3 24
$2.1B
$6.8B
Q2 24
$1.4B
$6.4B
Total Assets
ILMN
ILMN
SSNC
SSNC
Q1 26
$20.3B
Q4 25
$6.6B
$20.7B
Q3 25
$19.5B
Q2 25
$19.0B
Q1 25
$20.4B
Q4 24
$6.3B
$19.0B
Q3 24
$6.0B
$18.4B
Q2 24
$6.1B
$16.9B
Debt / Equity
ILMN
ILMN
SSNC
SSNC
Q1 26
1.08×
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ILMN
ILMN
SSNC
SSNC
Operating Cash FlowLast quarter
$321.0M
$299.7M
Free Cash FlowOCF − Capex
$267.0M
FCF MarginFCF / Revenue
23.0%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
0.96×
1.33×
TTM Free Cash FlowTrailing 4 quarters
$935.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ILMN
ILMN
SSNC
SSNC
Q1 26
$299.7M
Q4 25
$321.0M
$643.5M
Q3 25
$456.2M
Q2 25
$372.9M
Q1 25
$272.2M
Q4 24
$364.0M
$486.6M
Q3 24
$316.0M
$336.6M
Q2 24
$80.0M
$384.9M
Free Cash Flow
ILMN
ILMN
SSNC
SSNC
Q1 26
Q4 25
$267.0M
$633.0M
Q3 25
$421.5M
Q2 25
$350.0M
Q1 25
$259.5M
Q4 24
$335.0M
$466.9M
Q3 24
$284.0M
$310.7M
Q2 24
$49.0M
$374.9M
FCF Margin
ILMN
ILMN
SSNC
SSNC
Q1 26
Q4 25
23.0%
38.3%
Q3 25
26.9%
Q2 25
22.8%
Q1 25
17.1%
Q4 24
30.3%
30.5%
Q3 24
26.3%
21.2%
Q2 24
4.4%
25.8%
Capex Intensity
ILMN
ILMN
SSNC
SSNC
Q1 26
0.0%
Q4 25
0.6%
Q3 25
2.2%
Q2 25
1.5%
Q1 25
0.8%
Q4 24
2.6%
1.3%
Q3 24
3.0%
1.8%
Q2 24
2.8%
0.7%
Cash Conversion
ILMN
ILMN
SSNC
SSNC
Q1 26
1.33×
Q4 25
0.96×
3.33×
Q3 25
2.17×
Q2 25
2.06×
Q1 25
1.28×
Q4 24
1.96×
1.96×
Q3 24
0.45×
2.05×
Q2 24
2.02×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ILMN
ILMN

Product revenue$990.0M85%
Service and other revenue$169.0M15%

SSNC
SSNC

Technology-enabled services$1.4B85%
License, maintenance and related$239.8M15%

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