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Side-by-side financial comparison of INDEPENDENT BANK CORP (INDB) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

INDEPENDENT BANK CORP is the larger business by last-quarter revenue ($212.5M vs $148.5M, roughly 1.4× OPKO HEALTH, INC.). INDEPENDENT BANK CORP runs the higher net margin — 35.5% vs -21.1%, a 56.5% gap on every dollar of revenue. On growth, INDEPENDENT BANK CORP posted the faster year-over-year revenue change (46.9% vs -19.2%). INDEPENDENT BANK CORP produced more free cash flow last quarter ($75.5M vs $-28.6M). Over the past eight quarters, INDEPENDENT BANK CORP's revenue compounded faster (24.3% CAGR vs -7.5%).

Independent Bank is a bank headquartered in Grand Rapids, Michigan. The bank has 62 branches, all of which are in Michigan.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

INDB vs OPK — Head-to-Head

Bigger by revenue
INDB
INDB
1.4× larger
INDB
$212.5M
$148.5M
OPK
Growing faster (revenue YoY)
INDB
INDB
+66.0% gap
INDB
46.9%
-19.2%
OPK
Higher net margin
INDB
INDB
56.5% more per $
INDB
35.5%
-21.1%
OPK
More free cash flow
INDB
INDB
$104.1M more FCF
INDB
$75.5M
$-28.6M
OPK
Faster 2-yr revenue CAGR
INDB
INDB
Annualised
INDB
24.3%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
INDB
INDB
OPK
OPK
Revenue
$212.5M
$148.5M
Net Profit
$75.3M
$-31.3M
Gross Margin
43.1%
Operating Margin
-25.8%
Net Margin
35.5%
-21.1%
Revenue YoY
46.9%
-19.2%
Net Profit YoY
50.6%
-322.8%
EPS (diluted)
$1.51
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
INDB
INDB
OPK
OPK
Q4 25
$212.5M
$148.5M
Q3 25
$203.3M
$151.7M
Q2 25
$147.5M
$156.8M
Q1 25
$145.5M
$150.0M
Q4 24
$144.7M
$183.6M
Q3 24
$141.7M
$173.6M
Q2 24
$137.9M
$182.2M
Q1 24
$137.4M
$173.7M
Net Profit
INDB
INDB
OPK
OPK
Q4 25
$75.3M
$-31.3M
Q3 25
$34.3M
$21.6M
Q2 25
$51.1M
$-148.4M
Q1 25
$44.4M
$-67.6M
Q4 24
$50.0M
$14.0M
Q3 24
$42.9M
$24.9M
Q2 24
$51.3M
$-10.3M
Q1 24
$47.8M
$-81.8M
Gross Margin
INDB
INDB
OPK
OPK
Q4 25
43.1%
Q3 25
32.9%
Q2 25
31.5%
Q1 25
28.4%
Q4 24
46.1%
Q3 24
23.1%
Q2 24
28.4%
Q1 24
24.2%
Operating Margin
INDB
INDB
OPK
OPK
Q4 25
-25.8%
Q3 25
21.8%
31.7%
Q2 25
44.6%
-38.3%
Q1 25
39.3%
-44.8%
Q4 24
-18.0%
Q3 24
39.0%
8.2%
Q2 24
48.1%
-33.9%
Q1 24
45.5%
-41.2%
Net Margin
INDB
INDB
OPK
OPK
Q4 25
35.5%
-21.1%
Q3 25
16.8%
14.3%
Q2 25
34.6%
-94.7%
Q1 25
30.5%
-45.1%
Q4 24
34.6%
7.6%
Q3 24
30.3%
14.3%
Q2 24
37.2%
-5.7%
Q1 24
34.8%
-47.1%
EPS (diluted)
INDB
INDB
OPK
OPK
Q4 25
$1.51
$-0.04
Q3 25
$0.69
$0.03
Q2 25
$1.20
$-0.19
Q1 25
$1.04
$-0.10
Q4 24
$1.18
$0.02
Q3 24
$1.01
$0.03
Q2 24
$1.21
$-0.01
Q1 24
$1.12
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
INDB
INDB
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$364.4M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$3.6B
$1.3B
Total Assets
$24.9B
$1.9B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
INDB
INDB
OPK
OPK
Q4 25
$364.4M
Q3 25
$412.0M
Q2 25
$267.3M
Q1 25
$428.8M
Q4 24
$426.6M
Q3 24
$400.1M
Q2 24
$40.6M
Q1 24
$75.6M
Total Debt
INDB
INDB
OPK
OPK
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
INDB
INDB
OPK
OPK
Q4 25
$3.6B
$1.3B
Q3 25
$3.5B
$1.3B
Q2 25
$3.1B
$1.3B
Q1 25
$3.0B
$1.3B
Q4 24
$3.0B
$1.4B
Q3 24
$3.0B
$1.4B
Q2 24
$2.9B
$1.4B
Q1 24
$2.9B
$1.3B
Total Assets
INDB
INDB
OPK
OPK
Q4 25
$24.9B
$1.9B
Q3 25
$25.0B
$2.0B
Q2 25
$20.0B
$2.0B
Q1 25
$19.9B
$2.1B
Q4 24
$19.4B
$2.2B
Q3 24
$19.4B
$2.3B
Q2 24
$19.4B
$2.0B
Q1 24
$19.3B
$2.0B
Debt / Equity
INDB
INDB
OPK
OPK
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
INDB
INDB
OPK
OPK
Operating Cash FlowLast quarter
$78.9M
$-25.9M
Free Cash FlowOCF − Capex
$75.5M
$-28.6M
FCF MarginFCF / Revenue
35.5%
-19.3%
Capex IntensityCapex / Revenue
1.6%
1.8%
Cash ConversionOCF / Net Profit
1.05×
TTM Free Cash FlowTrailing 4 quarters
$239.0M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
INDB
INDB
OPK
OPK
Q4 25
$78.9M
$-25.9M
Q3 25
$52.2M
$-34.6M
Q2 25
$106.7M
$-83.4M
Q1 25
$13.3M
$-34.6M
Q4 24
$42.9M
$-44.4M
Q3 24
$70.2M
$-77.1M
Q2 24
$65.6M
$-26.4M
Q1 24
$51.1M
$-35.6M
Free Cash Flow
INDB
INDB
OPK
OPK
Q4 25
$75.5M
$-28.6M
Q3 25
$49.7M
$-37.8M
Q2 25
$102.5M
$-86.7M
Q1 25
$11.3M
$-37.7M
Q4 24
$36.5M
$-49.8M
Q3 24
$64.4M
$-85.0M
Q2 24
$61.9M
$-33.7M
Q1 24
$46.7M
$-40.0M
FCF Margin
INDB
INDB
OPK
OPK
Q4 25
35.5%
-19.3%
Q3 25
24.4%
-24.9%
Q2 25
69.5%
-55.3%
Q1 25
7.8%
-25.2%
Q4 24
25.2%
-27.1%
Q3 24
45.4%
-49.0%
Q2 24
44.9%
-18.5%
Q1 24
34.0%
-23.0%
Capex Intensity
INDB
INDB
OPK
OPK
Q4 25
1.6%
1.8%
Q3 25
1.2%
2.1%
Q2 25
2.9%
2.1%
Q1 25
1.4%
2.1%
Q4 24
4.4%
2.9%
Q3 24
4.1%
4.6%
Q2 24
2.7%
4.0%
Q1 24
3.2%
2.6%
Cash Conversion
INDB
INDB
OPK
OPK
Q4 25
1.05×
Q3 25
1.52×
-1.60×
Q2 25
2.09×
Q1 25
0.30×
Q4 24
0.86×
-3.17×
Q3 24
1.64×
-3.10×
Q2 24
1.28×
Q1 24
1.07×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

INDB
INDB

Segment breakdown not available.

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

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