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Side-by-side financial comparison of Jazz Pharmaceuticals plc (JAZZ) and BeOne Medicines Ltd. (ONC). Click either name above to swap in a different company.

BeOne Medicines Ltd. is the larger business by last-quarter revenue ($1.5B vs $1.2B, roughly 1.3× Jazz Pharmaceuticals plc). Jazz Pharmaceuticals plc runs the higher net margin — 17.0% vs 4.4%, a 12.5% gap on every dollar of revenue. On growth, BeOne Medicines Ltd. posted the faster year-over-year revenue change (32.8% vs 10.1%). BeOne Medicines Ltd. produced more free cash flow last quarter ($379.8M vs $345.8M). Over the past eight quarters, BeOne Medicines Ltd.'s revenue compounded faster (41.2% CAGR vs 15.2%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

BeOne Medicines, formerly known as BeiGene, Ltd. is a multinational oncology company. It specializes in the development of drugs for cancer treatment.

JAZZ vs ONC — Head-to-Head

Bigger by revenue
ONC
ONC
1.3× larger
ONC
$1.5B
$1.2B
JAZZ
Growing faster (revenue YoY)
ONC
ONC
+22.8% gap
ONC
32.8%
10.1%
JAZZ
Higher net margin
JAZZ
JAZZ
12.5% more per $
JAZZ
17.0%
4.4%
ONC
More free cash flow
ONC
ONC
$34.0M more FCF
ONC
$379.8M
$345.8M
JAZZ
Faster 2-yr revenue CAGR
ONC
ONC
Annualised
ONC
41.2%
15.2%
JAZZ

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
JAZZ
JAZZ
ONC
ONC
Revenue
$1.2B
$1.5B
Net Profit
$203.5M
$66.5M
Gross Margin
90.5%
Operating Margin
21.2%
12.4%
Net Margin
17.0%
4.4%
Revenue YoY
10.1%
32.8%
Net Profit YoY
6.5%
143.8%
EPS (diluted)
$3.34
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
JAZZ
JAZZ
ONC
ONC
Q4 25
$1.2B
$1.5B
Q3 25
$1.1B
$1.4B
Q2 25
$1.0B
$1.3B
Q1 25
$897.8M
$1.1B
Q4 24
$1.1B
$1.1B
Q3 24
$1.1B
$1.0B
Q2 24
$1.0B
$929.2M
Q1 24
$902.0M
$751.7M
Net Profit
JAZZ
JAZZ
ONC
ONC
Q4 25
$203.5M
$66.5M
Q3 25
$251.4M
$124.8M
Q2 25
$-718.5M
$94.3M
Q1 25
$-92.5M
$1.3M
Q4 24
$191.1M
$-151.9M
Q3 24
$215.1M
$-121.3M
Q2 24
$168.6M
$-120.4M
Q1 24
$-14.6M
$-251.2M
Gross Margin
JAZZ
JAZZ
ONC
ONC
Q4 25
90.5%
Q3 25
86.1%
Q2 25
87.5%
Q1 25
85.2%
Q4 24
85.8%
Q3 24
83.0%
Q2 24
85.1%
Q1 24
83.4%
Operating Margin
JAZZ
JAZZ
ONC
ONC
Q4 25
21.2%
12.4%
Q3 25
5.1%
11.5%
Q2 25
-65.6%
6.7%
Q1 25
-6.2%
1.0%
Q4 24
17.5%
-7.0%
Q3 24
24.7%
-12.0%
Q2 24
19.5%
-11.5%
Q1 24
7.3%
-34.8%
Net Margin
JAZZ
JAZZ
ONC
ONC
Q4 25
17.0%
4.4%
Q3 25
22.3%
8.8%
Q2 25
-68.7%
7.2%
Q1 25
-10.3%
0.1%
Q4 24
17.6%
-13.5%
Q3 24
20.4%
-12.1%
Q2 24
16.5%
-13.0%
Q1 24
-1.6%
-33.4%
EPS (diluted)
JAZZ
JAZZ
ONC
ONC
Q4 25
$3.34
$0.05
Q3 25
$4.08
$0.08
Q2 25
$-11.74
$0.06
Q1 25
$-1.52
$0.00
Q4 24
$2.97
$-0.10
Q3 24
$3.42
$-0.09
Q2 24
$2.49
$-0.09
Q1 24
$-0.23
$-0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
JAZZ
JAZZ
ONC
ONC
Cash + ST InvestmentsLiquidity on hand
$1.4B
$4.5B
Total DebtLower is stronger
$5.4B
$836.4M
Stockholders' EquityBook value
$4.3B
$4.4B
Total Assets
$11.7B
$8.2B
Debt / EquityLower = less leverage
1.24×
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
JAZZ
JAZZ
ONC
ONC
Q4 25
$1.4B
$4.5B
Q3 25
$1.3B
$4.0B
Q2 25
$1.2B
$2.8B
Q1 25
$1.9B
$2.5B
Q4 24
$2.4B
$2.6B
Q3 24
$2.2B
$2.7B
Q2 24
$1.4B
$2.6B
Q1 24
$1.4B
$2.8B
Total Debt
JAZZ
JAZZ
ONC
ONC
Q4 25
$5.4B
$836.4M
Q3 25
$5.4B
Q2 25
$5.4B
Q1 25
$5.4B
Q4 24
$6.1B
Q3 24
$6.1B
Q2 24
$5.7B
Q1 24
$5.7B
Stockholders' Equity
JAZZ
JAZZ
ONC
ONC
Q4 25
$4.3B
$4.4B
Q3 25
$4.0B
$4.1B
Q2 25
$3.7B
$3.8B
Q1 25
$4.2B
$3.5B
Q4 24
$4.1B
$3.3B
Q3 24
$4.2B
$3.4B
Q2 24
$3.8B
$3.4B
Q1 24
$3.7B
$3.4B
Total Assets
JAZZ
JAZZ
ONC
ONC
Q4 25
$11.7B
$8.2B
Q3 25
$11.4B
$7.6B
Q2 25
$10.9B
$6.3B
Q1 25
$11.5B
$5.8B
Q4 24
$12.0B
$5.9B
Q3 24
$12.3B
$5.8B
Q2 24
$11.4B
$5.7B
Q1 24
$11.3B
$5.7B
Debt / Equity
JAZZ
JAZZ
ONC
ONC
Q4 25
1.24×
0.19×
Q3 25
1.35×
Q2 25
1.45×
Q1 25
1.29×
Q4 24
1.49×
Q3 24
1.47×
Q2 24
1.52×
Q1 24
1.54×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
JAZZ
JAZZ
ONC
ONC
Operating Cash FlowLast quarter
$362.5M
$417.3M
Free Cash FlowOCF − Capex
$345.8M
$379.8M
FCF MarginFCF / Revenue
28.9%
25.4%
Capex IntensityCapex / Revenue
1.4%
2.5%
Cash ConversionOCF / Net Profit
1.78×
6.28×
TTM Free Cash FlowTrailing 4 quarters
$1.3B
$941.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
JAZZ
JAZZ
ONC
ONC
Q4 25
$362.5M
$417.3M
Q3 25
$474.6M
$402.6M
Q2 25
$88.9M
$263.6M
Q1 25
$429.8M
$44.1M
Q4 24
$398.6M
$75.2M
Q3 24
$398.7M
$188.4M
Q2 24
$331.4M
$-95.6M
Q1 24
$267.2M
$-308.6M
Free Cash Flow
JAZZ
JAZZ
ONC
ONC
Q4 25
$345.8M
$379.8M
Q3 25
$459.4M
$354.5M
Q2 25
$75.9M
$219.8M
Q1 25
$415.9M
$-12.3M
Q4 24
$385.3M
$-17.3M
Q3 24
$388.0M
$54.7M
Q2 24
$324.3M
$-205.5M
Q1 24
$260.3M
$-465.1M
FCF Margin
JAZZ
JAZZ
ONC
ONC
Q4 25
28.9%
25.4%
Q3 25
40.8%
25.1%
Q2 25
7.3%
16.7%
Q1 25
46.3%
-1.1%
Q4 24
35.4%
-1.5%
Q3 24
36.8%
5.5%
Q2 24
31.7%
-22.1%
Q1 24
28.9%
-61.9%
Capex Intensity
JAZZ
JAZZ
ONC
ONC
Q4 25
1.4%
2.5%
Q3 25
1.3%
3.4%
Q2 25
1.2%
3.3%
Q1 25
1.5%
5.0%
Q4 24
1.2%
8.2%
Q3 24
1.0%
13.3%
Q2 24
0.7%
11.8%
Q1 24
0.8%
20.8%
Cash Conversion
JAZZ
JAZZ
ONC
ONC
Q4 25
1.78×
6.28×
Q3 25
1.89×
3.22×
Q2 25
2.79×
Q1 25
34.71×
Q4 24
2.09×
Q3 24
1.85×
Q2 24
1.97×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

JAZZ
JAZZ

Xywav$465.5M39%
Total Oncology$337.8M28%
Rylaze Enrylaze$108.2M9%
Zepzelca$90.4M8%
Product And Services Royalties And Contract Revenue$65.5M5%
High Sodium AG Oxybate Product Royalty Revenue$55.7M5%
Xyrem$37.8M3%
Vyxeos$34.7M3%
Ziihera$8.5M1%
Other Products$2.8M0%
Sativex$1.5M0%

ONC
ONC

Segment breakdown not available.

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