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Side-by-side financial comparison of Karyopharm Therapeutics Inc. (KPTI) and MID PENN BANCORP INC (MPB). Click either name above to swap in a different company.
MID PENN BANCORP INC is the larger business by last-quarter revenue ($62.0M vs $34.1M, roughly 1.8× Karyopharm Therapeutics Inc.). MID PENN BANCORP INC runs the higher net margin — 31.4% vs -299.9%, a 331.2% gap on every dollar of revenue. On growth, MID PENN BANCORP INC posted the faster year-over-year revenue change (30.8% vs 11.6%). Over the past eight quarters, MID PENN BANCORP INC's revenue compounded faster (21.1% CAGR vs 1.4%).
Commerce Bancorp was a Cherry Hill, New Jersey–based bank created in 1973. In 2007, it was purchased by Toronto-Dominion Bank, which merged Commerce into TD Banknorth, the latter of which was rebranded to TD Bank.
KPTI vs MPB — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $34.1M | $62.0M |
| Net Profit | $-102.2M | $19.4M |
| Gross Margin | — | — |
| Operating Margin | -52.4% | 43.6% |
| Net Margin | -299.9% | 31.4% |
| Revenue YoY | 11.6% | 30.8% |
| Net Profit YoY | -232.0% | 47.0% |
| EPS (diluted) | $-7.02 | $0.83 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $34.1M | $62.0M | ||
| Q3 25 | $44.0M | $61.8M | ||
| Q2 25 | $37.9M | $54.3M | ||
| Q1 25 | $30.0M | $47.7M | ||
| Q4 24 | $30.5M | $47.4M | ||
| Q3 24 | $38.8M | $45.3M | ||
| Q2 24 | $42.8M | $44.1M | ||
| Q1 24 | $33.1M | $42.3M |
| Q4 25 | $-102.2M | $19.4M | ||
| Q3 25 | $-33.1M | $18.3M | ||
| Q2 25 | $-37.3M | $4.8M | ||
| Q1 25 | $-23.5M | $13.7M | ||
| Q4 24 | $-30.8M | $13.2M | ||
| Q3 24 | $-32.1M | $12.3M | ||
| Q2 24 | $23.8M | $11.8M | ||
| Q1 24 | $-37.4M | $12.1M |
| Q4 25 | -52.4% | 43.6% | ||
| Q3 25 | -34.6% | 39.3% | ||
| Q2 25 | -64.3% | 7.9% | ||
| Q1 25 | -110.8% | 35.2% | ||
| Q4 24 | -102.4% | 34.1% | ||
| Q3 24 | -67.8% | 32.8% | ||
| Q2 24 | -65.7% | 32.4% | ||
| Q1 24 | -101.9% | 34.8% |
| Q4 25 | -299.9% | 31.4% | ||
| Q3 25 | -75.2% | 29.6% | ||
| Q2 25 | -98.2% | 8.8% | ||
| Q1 25 | -78.2% | 28.8% | ||
| Q4 24 | -100.8% | 27.9% | ||
| Q3 24 | -82.7% | 27.1% | ||
| Q2 24 | 55.6% | 26.7% | ||
| Q1 24 | -112.8% | 28.7% |
| Q4 25 | $-7.02 | $0.83 | ||
| Q3 25 | $-3.82 | $0.79 | ||
| Q2 25 | $-4.32 | $0.22 | ||
| Q1 25 | $-2.77 | $0.71 | ||
| Q4 24 | $-2.33 | $0.72 | ||
| Q3 24 | $-3.85 | $0.74 | ||
| Q2 24 | $-2.97 | $0.71 | ||
| Q1 24 | $-4.85 | $0.73 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $60.5M | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-292.9M | $814.1M |
| Total Assets | $108.4M | $6.1B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $60.5M | — | ||
| Q3 25 | $37.7M | — | ||
| Q2 25 | $38.7M | — | ||
| Q1 25 | $38.8M | — | ||
| Q4 24 | $62.5M | — | ||
| Q3 24 | $72.8M | — | ||
| Q2 24 | $84.8M | — | ||
| Q1 24 | $30.6M | — |
| Q4 25 | $-292.9M | $814.1M | ||
| Q3 25 | $-269.3M | $796.3M | ||
| Q2 25 | $-238.9M | $775.7M | ||
| Q1 25 | $-205.9M | $667.9M | ||
| Q4 24 | $-186.0M | $655.0M | ||
| Q3 24 | $-159.6M | $573.1M | ||
| Q2 24 | $-132.1M | $559.7M | ||
| Q1 24 | $-169.0M | $551.0M |
| Q4 25 | $108.4M | $6.1B | ||
| Q3 25 | $96.2M | $6.3B | ||
| Q2 25 | $104.9M | $6.4B | ||
| Q1 25 | $127.7M | $5.5B | ||
| Q4 24 | $164.4M | $5.5B | ||
| Q3 24 | $189.5M | $5.5B | ||
| Q2 24 | $214.0M | $5.4B | ||
| Q1 24 | $204.5M | $5.3B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-11.8M | $80.0M |
| Free Cash FlowOCF − Capex | — | $71.8M |
| FCF MarginFCF / Revenue | — | 115.8% |
| Capex IntensityCapex / Revenue | 0.0% | 13.3% |
| Cash ConversionOCF / Net Profit | — | 4.12× |
| TTM Free Cash FlowTrailing 4 quarters | — | $132.1M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-11.8M | $80.0M | ||
| Q3 25 | $-5.9M | $26.3M | ||
| Q2 25 | $-18.7M | $29.0M | ||
| Q1 25 | $-39.0M | $11.5M | ||
| Q4 24 | $-25.8M | $51.4M | ||
| Q3 24 | $-19.5M | $16.9M | ||
| Q2 24 | $-38.5M | $18.0M | ||
| Q1 24 | $-43.7M | $12.4M |
| Q4 25 | — | $71.8M | ||
| Q3 25 | — | $24.3M | ||
| Q2 25 | — | $27.2M | ||
| Q1 25 | — | $8.8M | ||
| Q4 24 | $-25.9M | $44.5M | ||
| Q3 24 | — | $16.8M | ||
| Q2 24 | — | $17.7M | ||
| Q1 24 | $-43.9M | $12.1M |
| Q4 25 | — | 115.8% | ||
| Q3 25 | — | 39.4% | ||
| Q2 25 | — | 50.1% | ||
| Q1 25 | — | 18.4% | ||
| Q4 24 | -84.7% | 93.8% | ||
| Q3 24 | — | 37.1% | ||
| Q2 24 | — | 40.2% | ||
| Q1 24 | -132.6% | 28.5% |
| Q4 25 | 0.0% | 13.3% | ||
| Q3 25 | 0.0% | 3.1% | ||
| Q2 25 | 0.0% | 3.2% | ||
| Q1 25 | 0.0% | 5.7% | ||
| Q4 24 | 0.2% | 14.6% | ||
| Q3 24 | 0.0% | 0.0% | ||
| Q2 24 | 0.0% | 0.7% | ||
| Q1 24 | 0.6% | 0.8% |
| Q4 25 | — | 4.12× | ||
| Q3 25 | — | 1.44× | ||
| Q2 25 | — | 6.08× | ||
| Q1 25 | — | 0.84× | ||
| Q4 24 | — | 3.88× | ||
| Q3 24 | — | 1.37× | ||
| Q2 24 | -1.62× | 1.53× | ||
| Q1 24 | — | 1.02× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
KPTI
| Products | $32.1M | 94% |
| License And Other | $2.0M | 6% |
MPB
Segment breakdown not available.
