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Side-by-side financial comparison of Karyopharm Therapeutics Inc. (KPTI) and Vitesse Energy, Inc. (VTS). Click either name above to swap in a different company.
Vitesse Energy, Inc. is the larger business by last-quarter revenue ($58.6M vs $34.1M, roughly 1.7× Karyopharm Therapeutics Inc.). Vitesse Energy, Inc. runs the higher net margin — -1.3% vs -299.9%, a 298.6% gap on every dollar of revenue. On growth, Karyopharm Therapeutics Inc. posted the faster year-over-year revenue change (11.6% vs 4.8%). Over the past eight quarters, Karyopharm Therapeutics Inc.'s revenue compounded faster (1.4% CAGR vs -2.1%).
Vitesse Energy, Inc. is a U.S.-headquartered independent energy company focused on exploration, development, and production of oil and natural gas assets. It operates primarily in high-potential onshore basins including North Dakota's Williston Basin, serving domestic and global upstream energy market demand.
KPTI vs VTS — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $34.1M | $58.6M |
| Net Profit | $-102.2M | $-739.0K |
| Gross Margin | — | — |
| Operating Margin | -52.4% | -12.0% |
| Net Margin | -299.9% | -1.3% |
| Revenue YoY | 11.6% | 4.8% |
| Net Profit YoY | -232.0% | 85.6% |
| EPS (diluted) | $-7.02 | $-0.01 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $34.1M | $58.6M | ||
| Q3 25 | $44.0M | $67.4M | ||
| Q2 25 | $37.9M | $81.8M | ||
| Q1 25 | $30.0M | $66.2M | ||
| Q4 24 | $30.5M | $55.9M | ||
| Q3 24 | $38.8M | $58.3M | ||
| Q2 24 | $42.8M | $66.6M | ||
| Q1 24 | $33.1M | $61.2M |
| Q4 25 | $-102.2M | $-739.0K | ||
| Q3 25 | $-33.1M | $-1.3M | ||
| Q2 25 | $-37.3M | $24.7M | ||
| Q1 25 | $-23.5M | $2.7M | ||
| Q4 24 | $-30.8M | $-5.1M | ||
| Q3 24 | $-32.1M | $17.4M | ||
| Q2 24 | $23.8M | $10.9M | ||
| Q1 24 | $-37.4M | $-2.2M |
| Q4 25 | -52.4% | -12.0% | ||
| Q3 25 | -34.6% | 0.2% | ||
| Q2 25 | -64.3% | 22.8% | ||
| Q1 25 | -110.8% | 8.1% | ||
| Q4 24 | -102.4% | 3.7% | ||
| Q3 24 | -67.8% | 15.4% | ||
| Q2 24 | -65.7% | 25.2% | ||
| Q1 24 | -101.9% | 21.4% |
| Q4 25 | -299.9% | -1.3% | ||
| Q3 25 | -75.2% | -1.9% | ||
| Q2 25 | -98.2% | 30.2% | ||
| Q1 25 | -78.2% | 4.0% | ||
| Q4 24 | -100.8% | -9.2% | ||
| Q3 24 | -82.7% | 29.9% | ||
| Q2 24 | 55.6% | 16.4% | ||
| Q1 24 | -112.8% | -3.6% |
| Q4 25 | $-7.02 | $-0.01 | ||
| Q3 25 | $-3.82 | $-0.03 | ||
| Q2 25 | $-4.32 | $0.60 | ||
| Q1 25 | $-2.77 | $0.08 | ||
| Q4 24 | $-2.33 | $-0.15 | ||
| Q3 24 | $-3.85 | $0.53 | ||
| Q2 24 | $-2.97 | $0.33 | ||
| Q1 24 | $-4.85 | $-0.07 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $60.5M | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-292.9M | $629.3M |
| Total Assets | $108.4M | $893.4M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $60.5M | — | ||
| Q3 25 | $37.7M | — | ||
| Q2 25 | $38.7M | — | ||
| Q1 25 | $38.8M | $4.5M | ||
| Q4 24 | $62.5M | $3.0M | ||
| Q3 24 | $72.8M | — | ||
| Q2 24 | $84.8M | — | ||
| Q1 24 | $30.6M | — |
| Q4 25 | $-292.9M | $629.3M | ||
| Q3 25 | $-269.3M | $650.3M | ||
| Q2 25 | $-238.9M | $671.9M | ||
| Q1 25 | $-205.9M | $667.7M | ||
| Q4 24 | $-186.0M | $500.3M | ||
| Q3 24 | $-159.6M | $520.4M | ||
| Q2 24 | $-132.1M | $518.5M | ||
| Q1 24 | $-169.0M | $522.7M |
| Q4 25 | $108.4M | $893.4M | ||
| Q3 25 | $96.2M | $932.9M | ||
| Q2 25 | $104.9M | $951.5M | ||
| Q1 25 | $127.7M | $975.2M | ||
| Q4 24 | $164.4M | $810.9M | ||
| Q3 24 | $189.5M | $791.2M | ||
| Q2 24 | $214.0M | $778.4M | ||
| Q1 24 | $204.5M | $749.7M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-11.8M | $37.4M |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-11.8M | $37.4M | ||
| Q3 25 | $-5.9M | $49.4M | ||
| Q2 25 | $-18.7M | $66.0M | ||
| Q1 25 | $-39.0M | $17.5M | ||
| Q4 24 | $-25.8M | $34.7M | ||
| Q3 24 | $-19.5M | $45.7M | ||
| Q2 24 | $-38.5M | $35.2M | ||
| Q1 24 | $-43.7M | $39.4M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | $-25.9M | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | $-43.9M | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | -84.7% | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | -132.6% | — |
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.0% | — | ||
| Q1 25 | 0.0% | — | ||
| Q4 24 | 0.2% | — | ||
| Q3 24 | 0.0% | — | ||
| Q2 24 | 0.0% | — | ||
| Q1 24 | 0.6% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | 2.68× | ||
| Q1 25 | — | 6.56× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 2.62× | ||
| Q2 24 | -1.62× | 3.22× | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
KPTI
| Products | $32.1M | 94% |
| License And Other | $2.0M | 6% |
VTS
| Oil Reserves | $54.5M | 93% |
| Natural Gas Reserves | $4.2M | 7% |
