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Side-by-side financial comparison of Krystal Biotech, Inc. (KRYS) and REGIS CORP (RGS). Click either name above to swap in a different company.

Krystal Biotech, Inc. is the larger business by last-quarter revenue ($107.1M vs $57.1M, roughly 1.9× REGIS CORP). Krystal Biotech, Inc. runs the higher net margin — 48.0% vs 0.8%, a 47.2% gap on every dollar of revenue. On growth, REGIS CORP posted the faster year-over-year revenue change (22.3% vs 17.5%). Krystal Biotech, Inc. produced more free cash flow last quarter ($75.4M vs $891.0K). Over the past eight quarters, Krystal Biotech, Inc.'s revenue compounded faster (53.8% CAGR vs 7.8%).

Krystal Biotech, Inc. is a clinical-stage biotechnology company specializing in the research, development and commercialization of novel gene therapies for rare, serious dermatological diseases with high unmet medical needs. It primarily serves patients across North America and Europe, focusing on monogenic skin disorders that lack effective standard treatment options.

Regis Corporation is an American operator of hair salons. As of August 2021, it has 5,563 franchised and 276 company-owned salons. Its headquarters are in Minneapolis, Minnesota.

KRYS vs RGS — Head-to-Head

Bigger by revenue
KRYS
KRYS
1.9× larger
KRYS
$107.1M
$57.1M
RGS
Growing faster (revenue YoY)
RGS
RGS
+4.7% gap
RGS
22.3%
17.5%
KRYS
Higher net margin
KRYS
KRYS
47.2% more per $
KRYS
48.0%
0.8%
RGS
More free cash flow
KRYS
KRYS
$74.5M more FCF
KRYS
$75.4M
$891.0K
RGS
Faster 2-yr revenue CAGR
KRYS
KRYS
Annualised
KRYS
53.8%
7.8%
RGS

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
KRYS
KRYS
RGS
RGS
Revenue
$107.1M
$57.1M
Net Profit
$51.4M
$456.0K
Gross Margin
Operating Margin
41.5%
10.8%
Net Margin
48.0%
0.8%
Revenue YoY
17.5%
22.3%
Net Profit YoY
13.0%
-94.0%
EPS (diluted)
$1.69
$0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
KRYS
KRYS
RGS
RGS
Q4 25
$107.1M
$57.1M
Q3 25
$97.8M
$59.0M
Q2 25
$96.0M
$60.4M
Q1 25
$88.2M
$57.0M
Q4 24
$91.1M
$46.7M
Q3 24
$83.8M
$46.1M
Q2 24
$70.3M
$49.4M
Q1 24
$45.3M
$49.2M
Net Profit
KRYS
KRYS
RGS
RGS
Q4 25
$51.4M
$456.0K
Q3 25
$79.4M
$1.4M
Q2 25
$38.3M
$116.5M
Q1 25
$35.7M
$250.0K
Q4 24
$45.5M
$7.6M
Q3 24
$27.2M
$-853.0K
Q2 24
$15.6M
$91.2M
Q1 24
$932.0K
$-2.3M
Operating Margin
KRYS
KRYS
RGS
RGS
Q4 25
41.5%
10.8%
Q3 25
42.3%
10.0%
Q2 25
40.9%
12.1%
Q1 25
41.0%
8.8%
Q4 24
45.4%
11.8%
Q3 24
26.8%
4.6%
Q2 24
12.2%
Q1 24
-14.8%
8.3%
Net Margin
KRYS
KRYS
RGS
RGS
Q4 25
48.0%
0.8%
Q3 25
81.2%
2.3%
Q2 25
39.9%
192.9%
Q1 25
40.5%
0.4%
Q4 24
49.9%
16.4%
Q3 24
32.4%
-1.9%
Q2 24
22.2%
184.7%
Q1 24
2.1%
-4.7%
EPS (diluted)
KRYS
KRYS
RGS
RGS
Q4 25
$1.69
$0.16
Q3 25
$2.66
$0.49
Q2 25
$1.29
$43.67
Q1 25
$1.20
$0.08
Q4 24
$1.53
$2.71
Q3 24
$0.91
$-0.36
Q2 24
$0.53
$38.40
Q1 24
$0.03
$-1.00

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
KRYS
KRYS
RGS
RGS
Cash + ST InvestmentsLiquidity on hand
$496.3M
$18.4M
Total DebtLower is stronger
$113.3M
Stockholders' EquityBook value
$1.2B
$188.7M
Total Assets
$1.3B
$588.3M
Debt / EquityLower = less leverage
0.60×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
KRYS
KRYS
RGS
RGS
Q4 25
$496.3M
$18.4M
Q3 25
$392.6M
$16.6M
Q2 25
$353.8M
$17.0M
Q1 25
$308.8M
$13.3M
Q4 24
$344.9M
$10.2M
Q3 24
$374.0M
$6.3M
Q2 24
$345.8M
$10.1M
Q1 24
$359.0M
$5.9M
Total Debt
KRYS
KRYS
RGS
RGS
Q4 25
$113.3M
Q3 25
$111.3M
Q2 25
$110.8M
Q1 25
$112.0M
Q4 24
$111.5M
Q3 24
$95.2M
Q2 24
$99.5M
Q1 24
$179.7M
Stockholders' Equity
KRYS
KRYS
RGS
RGS
Q4 25
$1.2B
$188.7M
Q3 25
$1.1B
$187.6M
Q2 25
$1.0B
$185.6M
Q1 25
$984.7M
$68.6M
Q4 24
$946.4M
$66.7M
Q3 24
$885.8M
$56.4M
Q2 24
$838.9M
$56.8M
Q1 24
$799.2M
$-35.8M
Total Assets
KRYS
KRYS
RGS
RGS
Q4 25
$1.3B
$588.3M
Q3 25
$1.2B
$592.1M
Q2 25
$1.1B
$599.0M
Q1 25
$1.1B
$511.2M
Q4 24
$1.1B
$530.1M
Q3 24
$982.3M
$508.9M
Q2 24
$917.7M
$530.5M
Q1 24
$853.3M
$543.7M
Debt / Equity
KRYS
KRYS
RGS
RGS
Q4 25
0.60×
Q3 25
0.59×
Q2 25
0.60×
Q1 25
1.63×
Q4 24
1.67×
Q3 24
1.69×
Q2 24
1.75×
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
KRYS
KRYS
RGS
RGS
Operating Cash FlowLast quarter
$77.5M
$1.7M
Free Cash FlowOCF − Capex
$75.4M
$891.0K
FCF MarginFCF / Revenue
70.4%
1.6%
Capex IntensityCapex / Revenue
2.0%
1.4%
Cash ConversionOCF / Net Profit
1.51×
3.65×
TTM Free Cash FlowTrailing 4 quarters
$188.9M
$14.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
KRYS
KRYS
RGS
RGS
Q4 25
$77.5M
$1.7M
Q3 25
$39.7M
$2.3M
Q2 25
$52.7M
$6.8M
Q1 25
$31.0M
$6.2M
Q4 24
$52.8M
$2.1M
Q3 24
$58.9M
$-1.3M
Q2 24
$-4.2M
$5.1M
Q1 24
$15.9M
$-277.0K
Free Cash Flow
KRYS
KRYS
RGS
RGS
Q4 25
$75.4M
$891.0K
Q3 25
$38.0M
$1.9M
Q2 25
$50.8M
$6.2M
Q1 25
$24.8M
$5.9M
Q4 24
$52.0M
$1.7M
Q3 24
$57.8M
$-1.4M
Q2 24
$-5.3M
$5.1M
Q1 24
$14.6M
$-326.0K
FCF Margin
KRYS
KRYS
RGS
RGS
Q4 25
70.4%
1.6%
Q3 25
38.8%
3.2%
Q2 25
52.9%
10.3%
Q1 25
28.1%
10.3%
Q4 24
57.1%
3.6%
Q3 24
69.0%
-3.0%
Q2 24
-7.5%
10.3%
Q1 24
32.3%
-0.7%
Capex Intensity
KRYS
KRYS
RGS
RGS
Q4 25
2.0%
1.4%
Q3 25
1.7%
0.7%
Q2 25
2.0%
0.9%
Q1 25
7.0%
0.6%
Q4 24
0.9%
0.9%
Q3 24
1.2%
0.0%
Q2 24
1.6%
0.0%
Q1 24
2.8%
0.1%
Cash Conversion
KRYS
KRYS
RGS
RGS
Q4 25
1.51×
3.65×
Q3 25
0.50×
1.68×
Q2 25
1.38×
0.06×
Q1 25
0.87×
24.80×
Q4 24
1.16×
0.28×
Q3 24
2.17×
Q2 24
-0.27×
0.06×
Q1 24
17.05×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

KRYS
KRYS

Segment breakdown not available.

RGS
RGS

Franchise Segment$37.9M66%
Royalty$13.6M24%
Other$2.8M5%
Fees$1.8M3%
Franchise Fees$1.0M2%

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