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Side-by-side financial comparison of NEUROCRINE BIOSCIENCES INC (NBIX) and Revolution Medicines, Inc. (RVMD). Click either name above to swap in a different company.

NEUROCRINE BIOSCIENCES INC produced more free cash flow last quarter ($386.0M vs $-139.5M). Over the past eight quarters, NEUROCRINE BIOSCIENCES INC's revenue compounded faster (25.0% CAGR vs -100.0%).

Neurocrine Biosciences, Inc. is an American biopharmaceutical company founded in 1992. It is headquartered in San Diego, California, and led by CEO Kyle Gano as of October 11, 2024. Neurocrine develops treatments for neurological and endocrine-related diseases and disorders. In 2017, the company's drug valbenazine (Ingrezza) was approved in the US to treat adults with tardive dyskinesia (TD).

Tempus AI, Inc. is an American health technology company founded in 2015 by Eric Lefkofsky in Chicago, Illinois. It was established by Lefkofsky soon after his wife was diagnosed with breast cancer. Tempus uses data and artificial intelligence (AI) to create precision medicine services, including diagnostics, for oncology, cardiology, radiology, and depression. The company went public on the Nasdaq on June 14, 2024, under the ticker symbol "TEM."

NBIX vs RVMD — Head-to-Head

Bigger by revenue
NBIX
NBIX
Infinity× larger
NBIX
$805.5M
$0
RVMD
More free cash flow
NBIX
NBIX
$525.5M more FCF
NBIX
$386.0M
$-139.5M
RVMD
Faster 2-yr revenue CAGR
NBIX
NBIX
Annualised
NBIX
25.0%
-100.0%
RVMD

Income Statement — Q4 2025 vs Q4 2024

Metric
NBIX
NBIX
RVMD
RVMD
Revenue
$805.5M
$0
Net Profit
$153.7M
$-194.6M
Gross Margin
97.8%
Operating Margin
26.2%
Net Margin
19.1%
Revenue YoY
28.3%
Net Profit YoY
49.1%
-20.4%
EPS (diluted)
$1.49
$-1.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NBIX
NBIX
RVMD
RVMD
Q4 25
$805.5M
Q3 25
$794.9M
Q2 25
$687.5M
Q1 25
$572.6M
Q4 24
$627.7M
$0
Q3 24
$622.1M
$0
Q2 24
$590.2M
$0
Q1 24
$515.3M
$0
Net Profit
NBIX
NBIX
RVMD
RVMD
Q4 25
$153.7M
Q3 25
$209.5M
Q2 25
$107.5M
Q1 25
$7.9M
Q4 24
$103.1M
$-194.6M
Q3 24
$129.8M
$-156.3M
Q2 24
$65.0M
$-133.2M
Q1 24
$43.4M
$-116.0M
Gross Margin
NBIX
NBIX
RVMD
RVMD
Q4 25
97.8%
Q3 25
98.2%
Q2 25
98.4%
Q1 25
98.4%
Q4 24
98.5%
Q3 24
98.7%
Q2 24
98.4%
Q1 24
98.5%
Operating Margin
NBIX
NBIX
RVMD
RVMD
Q4 25
26.2%
Q3 25
30.1%
Q2 25
21.2%
Q1 25
4.1%
Q4 24
22.6%
Q3 24
29.5%
Q2 24
24.6%
Q1 24
19.3%
Net Margin
NBIX
NBIX
RVMD
RVMD
Q4 25
19.1%
Q3 25
26.4%
Q2 25
15.6%
Q1 25
1.4%
Q4 24
16.4%
Q3 24
20.9%
Q2 24
11.0%
Q1 24
8.4%
EPS (diluted)
NBIX
NBIX
RVMD
RVMD
Q4 25
$1.49
Q3 25
$2.04
Q2 25
$1.06
Q1 25
$0.08
Q4 24
$1.00
$-1.13
Q3 24
$1.24
$-0.94
Q2 24
$0.63
$-0.81
Q1 24
$0.42
$-0.70

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NBIX
NBIX
RVMD
RVMD
Cash + ST InvestmentsLiquidity on hand
$713.0M
$2.3B
Total DebtLower is stronger
Stockholders' EquityBook value
$3.3B
$2.3B
Total Assets
$4.6B
$2.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NBIX
NBIX
RVMD
RVMD
Q4 25
$713.0M
Q3 25
$340.2M
Q2 25
$264.0M
Q1 25
$194.1M
Q4 24
$233.0M
$2.3B
Q3 24
$349.1M
$1.5B
Q2 24
$139.7M
$1.6B
Q1 24
$396.3M
$1.7B
Stockholders' Equity
NBIX
NBIX
RVMD
RVMD
Q4 25
$3.3B
Q3 25
$3.0B
Q2 25
$2.7B
Q1 25
$2.5B
Q4 24
$2.6B
$2.3B
Q3 24
$2.7B
$1.6B
Q2 24
$2.5B
$1.6B
Q1 24
$2.4B
$1.7B
Total Assets
NBIX
NBIX
RVMD
RVMD
Q4 25
$4.6B
Q3 25
$4.3B
Q2 25
$3.9B
Q1 25
$3.7B
Q4 24
$3.7B
$2.6B
Q3 24
$3.5B
$1.8B
Q2 24
$3.3B
$1.8B
Q1 24
$3.5B
$1.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NBIX
NBIX
RVMD
RVMD
Operating Cash FlowLast quarter
$388.4M
$-138.3M
Free Cash FlowOCF − Capex
$386.0M
$-139.5M
FCF MarginFCF / Revenue
47.9%
Capex IntensityCapex / Revenue
0.3%
Cash ConversionOCF / Net Profit
2.53×
TTM Free Cash FlowTrailing 4 quarters
$743.9M
$-567.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NBIX
NBIX
RVMD
RVMD
Q4 25
$388.4M
Q3 25
$227.5M
Q2 25
$102.0M
Q1 25
$64.8M
Q4 24
$242.5M
$-138.3M
Q3 24
$158.0M
$-130.4M
Q2 24
$64.6M
$-128.2M
Q1 24
$130.3M
$-160.6M
Free Cash Flow
NBIX
NBIX
RVMD
RVMD
Q4 25
$386.0M
Q3 25
$214.3M
Q2 25
$89.5M
Q1 25
$54.1M
Q4 24
$235.2M
$-139.5M
Q3 24
$149.9M
$-133.9M
Q2 24
$53.0M
$-130.6M
Q1 24
$119.1M
$-163.7M
FCF Margin
NBIX
NBIX
RVMD
RVMD
Q4 25
47.9%
Q3 25
27.0%
Q2 25
13.0%
Q1 25
9.4%
Q4 24
37.5%
Q3 24
24.1%
Q2 24
9.0%
Q1 24
23.1%
Capex Intensity
NBIX
NBIX
RVMD
RVMD
Q4 25
0.3%
Q3 25
1.7%
Q2 25
1.8%
Q1 25
1.9%
Q4 24
1.2%
Q3 24
1.3%
Q2 24
2.0%
Q1 24
2.2%
Cash Conversion
NBIX
NBIX
RVMD
RVMD
Q4 25
2.53×
Q3 25
1.09×
Q2 25
0.95×
Q1 25
8.20×
Q4 24
2.35×
Q3 24
1.22×
Q2 24
0.99×
Q1 24
3.00×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NBIX
NBIX

INGREZZA Net Product Sales$653.8M81%
CRENESSITY Net Product Sales$135.4M17%
Other Income$12.6M2%
Collaboration Revenue$7.2M1%

RVMD
RVMD

Segment breakdown not available.

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