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Side-by-side financial comparison of Royalty Pharma plc (RPRX) and WINTRUST FINANCIAL CORP (WTFC). Click either name above to swap in a different company.

WINTRUST FINANCIAL CORP is the larger business by last-quarter revenue ($713.2M vs $622.0M, roughly 1.1× Royalty Pharma plc). Royalty Pharma plc runs the higher net margin — 34.4% vs 31.9%, a 2.6% gap on every dollar of revenue. On growth, WINTRUST FINANCIAL CORP posted the faster year-over-year revenue change (10.9% vs 4.8%). Over the past eight quarters, WINTRUST FINANCIAL CORP's revenue compounded faster (9.8% CAGR vs 4.6%).

Acceleron Pharma, Inc. is an American clinical stage biopharmaceutical company based in Cambridge, Massachusetts with a broad focus on developing medicines that regulate the transforming growth factor beta (TGF-β) superfamily of proteins, which play fundamental roles in the growth and repair of cells and tissues such as red blood cells, muscle, bone, and blood vessels.

Wintrust is a financial holding company in the United States that operates 15 chartered community banks in northern Illinois and southern Wisconsin. Wintrust is usually classified as a medium-sized banking institution in the United States and it trades on the Nasdaq Global Select Market with stock symbol WTFC. Wintrust is the second largest banking company in Chicago.

RPRX vs WTFC — Head-to-Head

Bigger by revenue
WTFC
WTFC
1.1× larger
WTFC
$713.2M
$622.0M
RPRX
Growing faster (revenue YoY)
WTFC
WTFC
+6.1% gap
WTFC
10.9%
4.8%
RPRX
Higher net margin
RPRX
RPRX
2.6% more per $
RPRX
34.4%
31.9%
WTFC
Faster 2-yr revenue CAGR
WTFC
WTFC
Annualised
WTFC
9.8%
4.6%
RPRX

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
RPRX
RPRX
WTFC
WTFC
Revenue
$622.0M
$713.2M
Net Profit
$214.2M
$227.4M
Gross Margin
Operating Margin
62.4%
Net Margin
34.4%
31.9%
Revenue YoY
4.8%
10.9%
Net Profit YoY
2.9%
EPS (diluted)
$0.49
$3.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RPRX
RPRX
WTFC
WTFC
Q1 26
$713.2M
Q4 25
$622.0M
$714.3M
Q3 25
$609.3M
$697.8M
Q2 25
$578.7M
$670.8M
Q1 25
$568.2M
$643.1M
Q4 24
$593.6M
$638.6M
Q3 24
$564.7M
$615.7M
Q2 24
$537.3M
$591.8M
Net Profit
RPRX
RPRX
WTFC
WTFC
Q1 26
$227.4M
Q4 25
$214.2M
Q3 25
$288.2M
$216.3M
Q2 25
$30.2M
$195.5M
Q1 25
$238.3M
$189.0M
Q4 24
$208.2M
Q3 24
$544.0M
$170.0M
Q2 24
$102.0M
$152.4M
Operating Margin
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
62.4%
42.3%
Q3 25
70.1%
42.4%
Q2 25
36.3%
39.8%
Q1 25
94.0%
39.3%
Q4 24
60.9%
39.6%
Q3 24
37.8%
Q2 24
50.2%
35.7%
Net Margin
RPRX
RPRX
WTFC
WTFC
Q1 26
31.9%
Q4 25
34.4%
Q3 25
47.3%
31.0%
Q2 25
5.2%
29.1%
Q1 25
41.9%
29.4%
Q4 24
35.1%
Q3 24
96.3%
27.6%
Q2 24
19.0%
25.8%
EPS (diluted)
RPRX
RPRX
WTFC
WTFC
Q1 26
$3.22
Q4 25
$0.49
$3.15
Q3 25
$0.67
$2.78
Q2 25
$0.07
$2.78
Q1 25
$0.55
$2.69
Q4 24
$0.46
$2.63
Q3 24
$1.21
$2.47
Q2 24
$0.23
$2.32

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RPRX
RPRX
WTFC
WTFC
Cash + ST InvestmentsLiquidity on hand
$618.7M
Total DebtLower is stronger
$9.0B
Stockholders' EquityBook value
$9.7B
$7.4B
Total Assets
$19.6B
$72.2B
Debt / EquityLower = less leverage
0.92×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
$618.7M
Q3 25
$938.9M
Q2 25
$631.9M
Q1 25
$1.1B
Q4 24
$929.0M
Q3 24
$950.1M
Q2 24
$1.8B
Total Debt
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
$9.0B
Q3 25
$8.9B
Q2 25
$8.0B
Q1 25
$7.6B
Q4 24
$7.6B
Q3 24
$7.6B
Q2 24
$7.6B
Stockholders' Equity
RPRX
RPRX
WTFC
WTFC
Q1 26
$7.4B
Q4 25
$9.7B
$7.3B
Q3 25
$9.6B
$7.0B
Q2 25
$9.5B
$7.2B
Q1 25
$9.8B
$6.6B
Q4 24
$10.3B
$6.3B
Q3 24
$10.3B
$6.4B
Q2 24
$9.8B
$5.5B
Total Assets
RPRX
RPRX
WTFC
WTFC
Q1 26
$72.2B
Q4 25
$19.6B
$71.1B
Q3 25
$19.3B
$69.6B
Q2 25
$18.3B
$69.0B
Q1 25
$17.6B
$65.9B
Q4 24
$18.2B
$64.9B
Q3 24
$18.0B
$63.8B
Q2 24
$17.7B
$59.8B
Debt / Equity
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
0.92×
Q3 25
0.93×
Q2 25
0.84×
Q1 25
0.78×
Q4 24
0.74×
Q3 24
0.74×
Q2 24
0.78×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RPRX
RPRX
WTFC
WTFC
Operating Cash FlowLast quarter
$827.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
3.86×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
$827.1M
$910.3M
Q3 25
$702.6M
$209.8M
Q2 25
$364.0M
$329.2M
Q1 25
$596.1M
$119.8M
Q4 24
$742.5M
$721.6M
Q3 24
$703.6M
$-61.6M
Q2 24
$658.2M
$221.2M
Free Cash Flow
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
$860.4M
Q3 25
Q2 25
Q1 25
Q4 24
$635.5M
Q3 24
$-78.3M
Q2 24
$182.1M
FCF Margin
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
120.5%
Q3 25
Q2 25
Q1 25
Q4 24
99.5%
Q3 24
-12.7%
Q2 24
30.8%
Capex Intensity
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
7.0%
Q3 25
Q2 25
Q1 25
Q4 24
13.5%
Q3 24
2.7%
Q2 24
6.6%
Cash Conversion
RPRX
RPRX
WTFC
WTFC
Q1 26
Q4 25
3.86×
Q3 25
2.44×
0.97×
Q2 25
12.06×
1.68×
Q1 25
2.50×
0.63×
Q4 24
3.57×
Q3 24
1.29×
-0.36×
Q2 24
6.45×
1.45×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RPRX
RPRX

Financial Royalty Assets$592.4M95%
Royalty Income Other$29.6M5%

WTFC
WTFC

Segment breakdown not available.

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