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Side-by-side financial comparison of RHYTHM PHARMACEUTICALS, INC. (RYTM) and Star Equity Holdings, Inc. (STRR). Click either name above to swap in a different company.
RHYTHM PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($57.3M vs $56.8M, roughly 1.0× Star Equity Holdings, Inc.). Star Equity Holdings, Inc. runs the higher net margin — -3.0% vs -83.0%, a 80.0% gap on every dollar of revenue. On growth, Star Equity Holdings, Inc. posted the faster year-over-year revenue change (69.0% vs 36.9%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 29.5%).
Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.
Artists Equity is an American production company founded by actors and filmmakers Ben Affleck and Matt Damon in November 2022.
RYTM vs STRR — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $57.3M | $56.8M |
| Net Profit | $-47.5M | $-1.7M |
| Gross Margin | 91.6% | — |
| Operating Margin | -82.2% | -0.2% |
| Net Margin | -83.0% | -3.0% |
| Revenue YoY | 36.9% | 69.0% |
| Net Profit YoY | -9.6% | -192.1% |
| EPS (diluted) | $-0.73 | $-0.49 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $57.3M | $56.8M | ||
| Q3 25 | $51.3M | $48.0M | ||
| Q2 25 | $48.5M | $35.5M | ||
| Q1 25 | $32.7M | $31.9M | ||
| Q4 24 | $41.8M | $33.6M | ||
| Q3 24 | $33.3M | $36.9M | ||
| Q2 24 | $29.1M | $35.7M | ||
| Q1 24 | $26.0M | $33.9M |
| Q4 25 | $-47.5M | $-1.7M | ||
| Q3 25 | $-52.9M | $-1.8M | ||
| Q2 25 | $-46.6M | $-688.0K | ||
| Q1 25 | $-49.5M | $-1.8M | ||
| Q4 24 | $-43.3M | $-585.0K | ||
| Q3 24 | $-43.6M | $-846.0K | ||
| Q2 24 | $-32.3M | $-441.0K | ||
| Q1 24 | $-141.4M | $-2.9M |
| Q4 25 | 91.6% | — | ||
| Q3 25 | 89.3% | 43.0% | ||
| Q2 25 | 88.6% | — | ||
| Q1 25 | 88.8% | — | ||
| Q4 24 | 90.9% | — | ||
| Q3 24 | 88.5% | 50.5% | ||
| Q2 24 | 89.9% | — | ||
| Q1 24 | 89.2% | — |
| Q4 25 | -82.2% | -0.2% | ||
| Q3 25 | -102.6% | -3.4% | ||
| Q2 25 | -93.4% | -0.6% | ||
| Q1 25 | -143.7% | -5.4% | ||
| Q4 24 | -98.6% | -0.4% | ||
| Q3 24 | -132.0% | -1.2% | ||
| Q2 24 | -139.2% | -0.5% | ||
| Q1 24 | -538.7% | -9.0% |
| Q4 25 | -83.0% | -3.0% | ||
| Q3 25 | -103.1% | -3.7% | ||
| Q2 25 | -96.1% | -1.9% | ||
| Q1 25 | -151.4% | -5.5% | ||
| Q4 24 | -103.6% | -1.7% | ||
| Q3 24 | -131.2% | -2.3% | ||
| Q2 24 | -110.9% | -1.2% | ||
| Q1 24 | -544.4% | -8.6% |
| Q4 25 | $-0.73 | $-0.49 | ||
| Q3 25 | $-0.82 | $-0.54 | ||
| Q2 25 | $-0.75 | $-0.23 | ||
| Q1 25 | $-0.81 | $-0.59 | ||
| Q4 24 | $-0.71 | $-0.21 | ||
| Q3 24 | $-0.73 | $-0.28 | ||
| Q2 24 | $-0.55 | $-0.15 | ||
| Q1 24 | $-2.35 | $-0.95 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $388.9M | $10.3M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $139.1M | $65.7M |
| Total Assets | $480.2M | $113.2M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $388.9M | $10.3M | ||
| Q3 25 | $416.1M | $15.4M | ||
| Q2 25 | $291.0M | $16.8M | ||
| Q1 25 | $314.5M | $16.6M | ||
| Q4 24 | $320.6M | $17.0M | ||
| Q3 24 | $298.4M | $15.8M | ||
| Q2 24 | $319.1M | $14.7M | ||
| Q1 24 | $201.2M | $20.4M |
| Q4 25 | — | — | ||
| Q3 25 | — | $6.5M | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | $0 | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $139.1M | $65.7M | ||
| Q3 25 | $148.8M | $67.8M | ||
| Q2 25 | $-11.9M | $40.1M | ||
| Q1 25 | $18.9M | $39.5M | ||
| Q4 24 | $21.7M | $40.4M | ||
| Q3 24 | $11.2M | $42.9M | ||
| Q2 24 | $39.3M | $42.6M | ||
| Q1 24 | $61.6M | $44.3M |
| Q4 25 | $480.2M | $113.2M | ||
| Q3 25 | $506.9M | $117.1M | ||
| Q2 25 | $372.7M | $55.6M | ||
| Q1 25 | $386.7M | $53.2M | ||
| Q4 24 | $392.3M | $52.6M | ||
| Q3 24 | $363.6M | $52.6M | ||
| Q2 24 | $381.8M | $52.6M | ||
| Q1 24 | $258.7M | $52.6M |
| Q4 25 | — | — | ||
| Q3 25 | — | 0.10× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.00× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-25.4M | $-7.3M |
| Free Cash FlowOCF − Capex | — | $-9.0M |
| FCF MarginFCF / Revenue | — | -15.8% |
| Capex IntensityCapex / Revenue | — | 3.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-13.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-25.4M | $-7.3M | ||
| Q3 25 | $-26.6M | $-2.7M | ||
| Q2 25 | $-23.3M | $139.0K | ||
| Q1 25 | $-40.4M | $-802.0K | ||
| Q4 24 | $-18.8M | $-2.8M | ||
| Q3 24 | $-25.2M | $1.3M | ||
| Q2 24 | $-29.1M | $-4.3M | ||
| Q1 24 | $-40.7M | $-1.8M |
| Q4 25 | — | $-9.0M | ||
| Q3 25 | — | $-3.4M | ||
| Q2 25 | — | $102.0K | ||
| Q1 25 | — | $-808.0K | ||
| Q4 24 | — | $-2.8M | ||
| Q3 24 | — | $1.3M | ||
| Q2 24 | — | $-4.3M | ||
| Q1 24 | — | $-1.8M |
| Q4 25 | — | -15.8% | ||
| Q3 25 | — | -7.0% | ||
| Q2 25 | — | 0.3% | ||
| Q1 25 | — | -2.5% | ||
| Q4 24 | — | -8.3% | ||
| Q3 24 | — | 3.4% | ||
| Q2 24 | — | -12.0% | ||
| Q1 24 | — | -5.3% |
| Q4 25 | — | 3.0% | ||
| Q3 25 | — | 1.3% | ||
| Q2 25 | — | 0.1% | ||
| Q1 25 | — | 0.0% | ||
| Q4 24 | — | 0.1% | ||
| Q3 24 | — | 0.0% | ||
| Q2 24 | — | 0.0% | ||
| Q1 24 | — | 0.0% |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
RYTM
Segment breakdown not available.
STRR
| Revenue From Other Contracts With Customers | $27.6M | 49% |
| Other | $24.3M | 43% |
| Energy Services Segment | $4.9M | 9% |
