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Side-by-side financial comparison of Spero Therapeutics, Inc. (SPRO) and UNIVERSAL HEALTH REALTY INCOME TRUST (UHT). Click either name above to swap in a different company.

UNIVERSAL HEALTH REALTY INCOME TRUST is the larger business by last-quarter revenue ($24.5M vs $12.6M, roughly 1.9× Spero Therapeutics, Inc.). Spero Therapeutics, Inc. runs the higher net margin — 250.7% vs 17.7%, a 233.0% gap on every dollar of revenue. On growth, Spero Therapeutics, Inc. posted the faster year-over-year revenue change (24080.8% vs -0.7%). Over the past eight quarters, Spero Therapeutics, Inc.'s revenue compounded faster (847.7% CAGR vs -1.3%).

Universal Health Services, Inc. (UHS) is an American Fortune 500 company that provides hospital and healthcare services, based in King of Prussia, Pennsylvania. In 2024, UHS reported total revenues of $15.8 billion.

SPRO vs UHT — Head-to-Head

Bigger by revenue
UHT
UHT
1.9× larger
UHT
$24.5M
$12.6M
SPRO
Growing faster (revenue YoY)
SPRO
SPRO
+24081.5% gap
SPRO
24080.8%
-0.7%
UHT
Higher net margin
SPRO
SPRO
233.0% more per $
SPRO
250.7%
17.7%
UHT
Faster 2-yr revenue CAGR
SPRO
SPRO
Annualised
SPRO
847.7%
-1.3%
UHT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
SPRO
SPRO
UHT
UHT
Revenue
$12.6M
$24.5M
Net Profit
$31.5M
$4.3M
Gross Margin
Operating Margin
34.7%
Net Margin
250.7%
17.7%
Revenue YoY
24080.8%
-0.7%
Net Profit YoY
250.9%
-7.2%
EPS (diluted)
$0.56
$0.32

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SPRO
SPRO
UHT
UHT
Q4 25
$12.6M
$24.5M
Q3 25
$0
$25.3M
Q2 25
$0
$24.9M
Q1 25
$12.0K
$24.5M
Q4 24
$52.0K
$24.6M
Q3 24
$65.0K
$24.5M
Q2 24
$114.0K
$24.7M
Q1 24
$140.0K
$25.1M
Net Profit
SPRO
SPRO
UHT
UHT
Q4 25
$31.5M
$4.3M
Q3 25
$-7.4M
$4.0M
Q2 25
$-1.7M
$4.5M
Q1 25
$-13.9M
$4.8M
Q4 24
$4.7M
Q3 24
$-17.1M
$4.0M
Q2 24
$-17.9M
$5.3M
Q1 24
$-12.7M
$5.3M
Operating Margin
SPRO
SPRO
UHT
UHT
Q4 25
34.7%
Q3 25
33.2%
Q2 25
35.6%
Q1 25
-122758.3%
36.8%
Q4 24
37.6%
Q3 24
-28604.6%
34.7%
Q2 24
-16720.2%
38.7%
Q1 24
-9987.1%
37.6%
Net Margin
SPRO
SPRO
UHT
UHT
Q4 25
250.7%
17.7%
Q3 25
15.9%
Q2 25
18.1%
Q1 25
-115550.0%
19.5%
Q4 24
18.9%
Q3 24
-26380.0%
16.3%
Q2 24
-15668.4%
21.3%
Q1 24
-9049.3%
21.1%
EPS (diluted)
SPRO
SPRO
UHT
UHT
Q4 25
$0.56
$0.32
Q3 25
$-0.13
$0.29
Q2 25
$-0.03
$0.32
Q1 25
$-0.25
$0.34
Q4 24
$0.34
Q3 24
$-0.32
$0.29
Q2 24
$-0.33
$0.38
Q1 24
$-0.24
$0.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SPRO
SPRO
UHT
UHT
Cash + ST InvestmentsLiquidity on hand
$40.3M
$6.7M
Total DebtLower is stronger
$374.8M
Stockholders' EquityBook value
$59.0M
$152.4M
Total Assets
$68.9M
$564.9M
Debt / EquityLower = less leverage
2.46×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SPRO
SPRO
UHT
UHT
Q4 25
$40.3M
$6.7M
Q3 25
$48.6M
$6.9M
Q2 25
$31.2M
$6.6M
Q1 25
$48.9M
$7.0M
Q4 24
$52.9M
$7.1M
Q3 24
$76.3M
$6.4M
Q2 24
$63.5M
$5.6M
Q1 24
$82.3M
$7.7M
Total Debt
SPRO
SPRO
UHT
UHT
Q4 25
$374.8M
Q3 25
Q2 25
Q1 25
Q4 24
$368.4M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
SPRO
SPRO
UHT
UHT
Q4 25
$59.0M
$152.4M
Q3 25
$26.5M
$158.6M
Q2 25
$32.8M
$165.2M
Q1 25
$33.8M
$172.2M
Q4 24
$46.1M
$179.5M
Q3 24
$65.5M
$181.6M
Q2 24
$80.5M
$190.7M
Q1 24
$96.2M
$196.5M
Total Assets
SPRO
SPRO
UHT
UHT
Q4 25
$68.9M
$564.9M
Q3 25
$54.2M
$568.0M
Q2 25
$62.1M
$573.0M
Q1 25
$77.7M
$573.5M
Q4 24
$110.5M
$580.9M
Q3 24
$135.2M
$584.3M
Q2 24
$149.9M
$586.6M
Q1 24
$167.7M
$596.2M
Debt / Equity
SPRO
SPRO
UHT
UHT
Q4 25
2.46×
Q3 25
Q2 25
Q1 25
Q4 24
2.05×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SPRO
SPRO
UHT
UHT
Operating Cash FlowLast quarter
$-8.4M
$49.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
-0.26×
11.35×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SPRO
SPRO
UHT
UHT
Q4 25
$-8.4M
$49.1M
Q3 25
$17.4M
$10.2M
Q2 25
$-17.7M
$13.7M
Q1 25
$-4.0M
$11.6M
Q4 24
$-23.4M
$46.9M
Q3 24
$12.8M
$9.9M
Q2 24
$-18.7M
$12.1M
Q1 24
$5.9M
$11.7M
Cash Conversion
SPRO
SPRO
UHT
UHT
Q4 25
-0.26×
11.35×
Q3 25
2.54×
Q2 25
3.05×
Q1 25
2.43×
Q4 24
10.06×
Q3 24
2.48×
Q2 24
2.30×
Q1 24
2.21×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

SPRO
SPRO

Segment breakdown not available.

UHT
UHT

Reportable Segment Aggregation Before Other Operating Segment$23.1M94%
Equity Method Investment Nonconsolidated Investee Or Group Of Investees$2.3M9%

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