EXACT SCIENCES CORP

EXACT SCIENCES CORPEXASEarnings & Financial Report

Nasdaq · health care industry

Exact Sciences Corporation is an American molecular diagnostics company based in Madison, Wisconsin, specializing in the detection of early-stage cancers. The company provides products for the detection and prevention of colorectal cancer, including Cologuard, the first stool DNA test for colorectal cancer, along with additional screening and precision oncological tests for other types of cancer.

Revenue

$850.7M

Gross Profit

$583.9M

Operating Profit

$-25.5M

Net Profit

$-19.6M

Gross Margin

68.6%

Operating Margin

-3.0%

Net Margin

-2.3%

YoY Growth

20.0%

EPS

$-0.10

Financial Flow

EXACT SCIENCES CORP Q3 2025 Financial Summary

EXACT SCIENCES CORP reported revenue of $850.7M (up 20.0% YoY) for Q3 2025, with a net profit of $-19.6M (up 48.8% YoY) (-2.3% margin). Cost of goods sold was $266.8M, operating expenses totaled $609.5M.

Key Financial Metrics

Total Revenue$850.7M
Net Profit$-19.6M
Gross Margin68.6%
Operating Margin-3.0%
Report PeriodQ3 2025

Revenue Breakdown

EXACT SCIENCES CORP Q3 2025 revenue of $850.7M breaks down across 2 segments, led by Screening at $666.2M (78.3% of total).

SegmentRevenue% of Total
Screening$666.2M78.3%
Precision Oncology$184.5M21.7%

EXACT SCIENCES CORP Revenue by Segment — Quarterly Trend

EXACT SCIENCES CORP revenue by segment across the last 4 reported quarters, showing how each business line (such as Screening and Precision Oncology) has evolved quarter over quarter.

SegmentQ4 2025Q3 2025Q2 2025Q1 2025
Screening$695.1M$666.2M$628.5M$540.0M
Precision Oncology$183.2M$184.5M$182.6M$166.8M

EXACT SCIENCES CORP Annual Revenue by Year

EXACT SCIENCES CORP annual revenue history includes year-by-year totals (for example, 2025 revenue was $3.2B).

YearAnnual Revenue
2025$3.2B
2024$2.8B
2023$2.5B
2022$2.1B

EXACT SCIENCES CORP Quarterly Revenue & Net Profit History

EXACT SCIENCES CORP results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 2025$878.4M+23.1%$-86.0M-9.8%
Q3 2025$850.7M+20.0%$-19.6M-2.3%
Q2 2025$811.1M+16.0%$-1.2M-0.1%
Q1 2025$706.8M+10.9%$-101.2M-14.3%
Q4 2024$713.4M+10.3%$-864.6M-121.2%
Q3 2024$708.7M+12.8%$-38.2M-5.4%
Q2 2024$699.3M+12.4%$-15.8M-2.3%
Q1 2024$637.5M+5.8%$-110.2M-17.3%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$637.5M$699.3M$708.7M$713.4M$706.8M$811.1M$850.7M$878.4M
YoY Growth5.8%12.4%12.8%10.3%10.9%16.0%20.0%23.1%

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$6.38B$6.67B$6.75B$5.93B$5.71B$5.80B$5.90B$5.86B
Liabilities$3.24B$3.48B$3.54B$3.53B$3.31B$3.33B$3.40B$3.46B
Equity$3.13B$3.19B$3.21B$2.40B$2.40B$2.47B$2.50B$2.40B

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-82.3M$107.1M$138.7M$47.1M$30.8M$89.0M$219.9M$151.7M