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Side-by-side financial comparison of Amgen (AMGN) and American Express (AXP). Click either name above to swap in a different company.

Amgen is the larger business by last-quarter revenue ($9.9B vs $18.9M, roughly 521.8× American Express). American Express runs the higher net margin — 15.7% vs 13.5%, a 2.2% gap on every dollar of revenue. On growth, American Express posted the faster year-over-year revenue change (11.4% vs 8.6%). Over the past eight quarters, Amgen's revenue compounded faster (15.1% CAGR vs -95.6%).

Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. The company is ranked 18th on the list of largest biomedical companies by revenue. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics.

American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...

AMGN vs AXP — Head-to-Head

Bigger by revenue
AMGN
AMGN
521.8× larger
AMGN
$9.9B
$18.9M
AXP
Growing faster (revenue YoY)
AXP
AXP
+2.8% gap
AXP
11.4%
8.6%
AMGN
Higher net margin
AXP
AXP
2.2% more per $
AXP
15.7%
13.5%
AMGN
Faster 2-yr revenue CAGR
AMGN
AMGN
Annualised
AMGN
15.1%
-95.6%
AXP

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
AMGN
AMGN
AXP
AXP
Revenue
$9.9B
$18.9M
Net Profit
$1.3B
$3.0M
Gross Margin
69.8%
Operating Margin
27.6%
Net Margin
13.5%
15.7%
Revenue YoY
8.6%
11.4%
Net Profit YoY
112.6%
15.0%
EPS (diluted)
$2.45

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMGN
AMGN
AXP
AXP
Q1 26
$18.9M
Q4 25
$9.9B
$10.9B
Q3 25
$9.6B
$10.4B
Q2 25
$9.2B
$10.3B
Q1 25
$8.1B
$9.6B
Q4 24
$9.1B
$10.0B
Q3 24
$8.5B
$9.7B
Q2 24
$8.4B
$9.8B
Net Profit
AMGN
AMGN
AXP
AXP
Q1 26
$3.0M
Q4 25
$1.3B
$2.5B
Q3 25
$3.2B
$2.9B
Q2 25
$1.4B
$2.9B
Q1 25
$1.7B
$2.6B
Q4 24
$627.0M
$2.2B
Q3 24
$2.8B
$2.5B
Q2 24
$746.0M
$3.0B
Gross Margin
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
69.8%
Q3 25
67.8%
Q2 25
67.2%
Q1 25
63.6%
Q4 24
65.7%
Q3 24
61.1%
Q2 24
61.4%
Operating Margin
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
27.6%
28.2%
Q3 25
26.4%
36.7%
Q2 25
28.9%
34.4%
Q1 25
14.5%
34.6%
Q4 24
25.4%
27.7%
Q3 24
24.1%
33.0%
Q2 24
22.8%
38.6%
Net Margin
AMGN
AMGN
AXP
AXP
Q1 26
15.7%
Q4 25
13.5%
22.5%
Q3 25
33.7%
27.9%
Q2 25
15.6%
28.0%
Q1 25
21.2%
26.8%
Q4 24
6.9%
21.8%
Q3 24
33.3%
25.8%
Q2 24
8.9%
30.7%
EPS (diluted)
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
$2.45
$3.52
Q3 25
$5.93
$4.14
Q2 25
$2.65
$4.08
Q1 25
$3.20
$3.64
Q4 24
$1.17
$3.04
Q3 24
$5.22
$3.49
Q2 24
$1.38
$4.15

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMGN
AMGN
AXP
AXP
Cash + ST InvestmentsLiquidity on hand
$9.1B
Total DebtLower is stronger
$54.6B
$60.4M
Stockholders' EquityBook value
$8.7B
$34.0M
Total Assets
$90.6B
$308.9M
Debt / EquityLower = less leverage
6.31×
1.78×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
$9.1B
$742.0M
Q3 25
$9.4B
$1.3B
Q2 25
$8.0B
$197.0M
Q1 25
$8.8B
$261.0M
Q4 24
$12.0B
$221.0M
Q3 24
$9.0B
$120.0M
Q2 24
$9.3B
$188.0M
Total Debt
AMGN
AMGN
AXP
AXP
Q1 26
$60.4M
Q4 25
$54.6B
$56.4B
Q3 25
$54.6B
$57.8B
Q2 25
$56.2B
$58.2B
Q1 25
$57.4B
$51.2B
Q4 24
$60.1B
$49.7B
Q3 24
$60.4B
$53.5B
Q2 24
$62.6B
$51.5B
Stockholders' Equity
AMGN
AMGN
AXP
AXP
Q1 26
$34.0M
Q4 25
$8.7B
$33.5B
Q3 25
$9.6B
$32.4B
Q2 25
$7.4B
$32.3B
Q1 25
$6.2B
$31.2B
Q4 24
$5.9B
$30.3B
Q3 24
$7.5B
$29.7B
Q2 24
$5.9B
$29.5B
Total Assets
AMGN
AMGN
AXP
AXP
Q1 26
$308.9M
Q4 25
$90.6B
$300.1B
Q3 25
$90.1B
$297.6B
Q2 25
$87.9B
$295.6B
Q1 25
$89.4B
$282.2B
Q4 24
$91.8B
$271.5B
Q3 24
$90.9B
$271.0B
Q2 24
$90.9B
$272.2B
Debt / Equity
AMGN
AMGN
AXP
AXP
Q1 26
1.78×
Q4 25
6.31×
1.68×
Q3 25
5.67×
1.78×
Q2 25
7.57×
1.80×
Q1 25
9.24×
1.64×
Q4 24
10.23×
1.64×
Q3 24
8.02×
1.80×
Q2 24
10.57×
1.74×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMGN
AMGN
AXP
AXP
Operating Cash FlowLast quarter
$1.6B
Free Cash FlowOCF − Capex
$961.0M
FCF MarginFCF / Revenue
9.7%
Capex IntensityCapex / Revenue
6.5%
Cash ConversionOCF / Net Profit
1.20×
TTM Free Cash FlowTrailing 4 quarters
$8.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
$1.6B
$3.1B
Q3 25
$4.7B
$6.2B
Q2 25
$2.3B
$4.4B
Q1 25
$1.4B
$4.8B
Q4 24
$4.8B
$5.8B
Q3 24
$3.6B
$-1.8B
Q2 24
$2.5B
$4.5B
Free Cash Flow
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
$961.0M
$2.3B
Q3 25
$4.2B
$5.6B
Q2 25
$1.9B
$3.7B
Q1 25
$980.0M
$4.3B
Q4 24
$4.4B
$5.3B
Q3 24
$3.3B
$-2.3B
Q2 24
$2.2B
$4.0B
FCF Margin
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
9.7%
21.4%
Q3 25
44.4%
53.6%
Q2 25
20.8%
36.3%
Q1 25
12.0%
45.0%
Q4 24
48.4%
53.1%
Q3 24
39.0%
-23.3%
Q2 24
26.5%
40.4%
Capex Intensity
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
6.5%
6.6%
Q3 25
4.6%
6.3%
Q2 25
4.0%
6.0%
Q1 25
5.0%
4.5%
Q4 24
4.1%
5.0%
Q3 24
3.0%
4.7%
Q2 24
2.8%
5.8%
Cash Conversion
AMGN
AMGN
AXP
AXP
Q1 26
Q4 25
1.20×
1.25×
Q3 25
1.46×
2.15×
Q2 25
1.59×
1.51×
Q1 25
0.80×
1.84×
Q4 24
7.61×
2.66×
Q3 24
1.26×
-0.72×
Q2 24
3.30×
1.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMGN
AMGN

Products$9.4B95%
Xgeva$291.0M3%
Vectibix$163.0M2%
Aranesp$115.0M1%

AXP
AXP

Discount revenue$9.5M50%
Other$8.9M47%
Deposits with banks and other$512.0K3%

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